Attention: World-2DPAGE is no longer maintained. Previously submitted data can still be queried at World-2DPAGE Repository.

World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0030]' for entry matching: O08583 World-2DPAGE Repository (0030):  O08583 O08583 General information about the entry View entry in simple text format Entry name THOC4_MOUSE Primary accession number O08583 integrated into World-2DPAGE Repository (0030) on  November 9, 2010 (release 1) 2D Annotations were last modified on June 21, 2011 (version 2) General Annotations were last modified on  November 23, 2011 (version 2) Name and origin of the protein Description RecName: Full=THO complex subunit 4; Short=Tho4; AltName: Full=Ally of AML-1 and LEF-1; AltName: Full=REF1-I; AltName: Full=RNA and export factor-binding protein 1; AltName: Full=Transcriptional coactivator Aly/REF;. Gene name Name=Thoc4 Synonyms=Aly, Ref1, Refbp1 Annotated species Rattus norvegicus (Rat) [TaxID: 10116] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000006; D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C. ''Two-dimensional gel proteome reference map of INS-1E cells'' Proteomics 11(7):1365-1369 (2011) 2D PAGE maps for identified proteins How to interpret a protein RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7} Rattus norvegicus (Rat)   map experimental info   RAT_INS1E_4-7 MAP LOCATIONS: SPOT 1880: pI=5.52; Mw=34583   [identification data] SPOT 1929: pI=6.10; Mw=33407   [identification data] IDENTIFICATION: SPOT 1880: Mascot protein score=55. Number of peptides=1 [1] SPOT 1929: Mascot protein score=42. Number of peptides=1 [1]. MAPPING (identification): SPOT 1880: Tandem mass spectrometry [1]; SPOT 1929: Tandem mass spectrometry [1]. Copyright Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium Cross-references UniProtKB/Swiss-Prot O08583; THOC4_MOUSE. World-2DPAGE Repository O08583; THOC4_MOUSE. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name THOC4_MOUSE Primary accession number O08583 Secondary accession number(s) Q0VBL5 Q8CBM4 Q9JJW7 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  November 16, 2011 (version 103) Name and origin of the protein Description RecName: Full=THO complex subunit 4; Short=Tho4; AltName: Full=Ally of AML-1 and LEF-1; AltName: Full=REF1-I; AltName: Full=RNA and export factor-binding protein 1; AltName: Full=Transcriptional coactivator Aly/REF; Gene name Name=Thoc4 Synonyms=Aly, Ref1, Refbp1 Encoded on Name=Thoc4; Synonyms=Aly, Ref1, Refbp1 Keywords 3D-structure; Acetylation; Alternative splicing; Chaperone; Complete proteome; Cytoplasm; Methylation; mRNA processing; mRNA splicing; mRNA transport; Nucleus; Phosphoprotein; Reference proteome; RNA-binding; Spliceosome; Transport. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U89876; AAC53117.1; -; mRNA EMBL AJ252140; CAB76383.1; -; mRNA EMBL AL663030; CAM27086.1; -; Genomic_DNA EMBL CH466558; EDL34770.1; -; Genomic_DNA EMBL BC120588; AAI20589.1; -; mRNA EMBL BC137658; AAI37659.1; -; mRNA EMBL AK035721; BAC29168.1; -; mRNA IPI IPI00114407; -; . IPI IPI00122339; -; . RefSeq NP_035698.1; NM_011568.1; . UniGene Mm.1886; -; . PDB 1NO8; NMR; -; A=77-182 PDBsum 1NO8; -; . ProteinModelPortal O08583; -; . SMR O08583; 1-187; . STRING O08583; -; . PhosphoSite O08583; -; . PRIDE O08583; -; . Ensembl ENSMUST00000026125; ENSMUSP00000026125; ENSMUSG00000025134; . GeneID 21681; -; . KEGG mmu:21681; -; . UCSC uc007mtl.1; mouse; . CTD 10189; -; . MGI MGI:1341044; Thoc4; . eggNOG roNOG17249; -; . GeneTree ENSGT00410000025615; -; . HOGENOM HBG608782; -; . HOVERGEN HBG054806; -; . InParanoid O08583; -; . OMA NGNFNGN; -; . OrthoDB EOG4MW87F; -; . NextBio 300988; -; . ArrayExpress O08583; -; . Bgee O08583; -; . CleanEx MM_THOC4; -; . Genevestigator O08583; -; . GermOnline ENSMUSG00000025134; Mus musculus; . GO GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell; . GO GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell; . GO GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW; . GO GO:0000166; F:nucleotide binding; IEA:InterPro; . GO GO:0003723; F:RNA binding; IDA:MGI; . GO GO:0003697; F:single-stranded DNA binding; IDA:MGI; . GO GO:0006397; P:mRNA processing; IEA:UniProtKB-KW; . GO GO:0051028; P:mRNA transport; IEA:UniProtKB-KW; . GO GO:0008380; P:RNA splicing; IEA:UniProtKB-KW; . InterPro IPR012677; Nucleotide-bd_a/b_plait; . InterPro IPR000504; RRM_dom; . Gene3D G3DSA:3.30.70.330; a_b_plait_nuc_bd; 1; . KO K12881; -; . Pfam PF00076; RRM_1; 1; . SMART SM00360; RRM; 1; . PROSITE PS50102; RRM; 1; . World-2DPAGE Repository (search AC)