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Searching in 'World-2DPAGE Repository [0019]' for entry matching: O08838

World-2DPAGE Repository (0019):  O08838


General information about the entry
View entry in simple text format
Entry nameAMPH_RAT
Primary accession numberO08838
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Amphiphysin;.
Gene nameName=Amph
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
  map experimental info

pI=4.57; Mw=74946  [identification data]
pI=4.57; Mw=74946  [identification data]

IDENTIFICATION: SPOT 1122: Peptides number=7. SeqCov=12.6%. MOWSE score=1.47E+7 [1]
SPOT 1192: Peptides number=3. SeqCov=6.3%. MOWSE score=9.47E+3 [1].
MAPPING (identification):
SPOT 1122: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1192: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Data from Dr. Willard Freeman, Penn State College of Medicine, USA
UniProtKB/Swiss-ProtO08838; AMPH_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameAMPH_RAT
Primary accession numberO08838
Sequence was last modified on July 1, 1997 (version 1)
Annotations were last modified on November 16, 2011 (version 99)
Name and origin of the protein
DescriptionRecName: Full=Amphiphysin;
Gene nameName=Amph
Encoded onName=Amph; Synonyms=Amph1
Keywords3D-structure; Cell junction; Coiled coil; Complete proteome; Cytoplasm; Cytoplasmic vesicle; Cytoskeleton; Direct protein sequencing; Membrane; Phosphoprotein; Reference proteome; SH3 domain; Synapse.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLY13381; CAA73808.1; -; mRNA
IPIIPI00196508; -; .
RefSeqNP_071553.1; NM_022217.1; .
UniGeneRn.44463; -; .
PDB2VJ0; X-ray; 1.60 A; Q=324-330
PDBsum2VJ0; -; .
ProteinModelPortalO08838; -; .
SMRO08838; 35-234; 604-683; .
IntActO08838; 2; .
MINTMINT-101171; -; .
STRINGO08838; -; .
PhosphoSiteO08838; -; .
PRIDEO08838; -; .
GeneID60668; -; .
KEGGrno:60668; -; .
CTD273; -; .
RGD620274; Amph; .
eggNOGroNOG04480; -; .
GeneTreeENSGT00390000017588; -; .
HOVERGENHBG004224; -; .
InParanoidO08838; -; .
OrthoDBEOG49078R; -; .
PhylomeDBO08838; -; .
NextBio612393; -; .
ArrayExpressO08838; -; .
GenevestigatorO08838; -; .
GermOnlineENSRNOG00000012490; Rattus norvegicus; .
GOGO:0043679; C:axon terminus; IDA:RGD; .
GOGO:0030054; C:cell junction; IEA:UniProtKB-KW; .
GOGO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell; .
GOGO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell; .
GOGO:0008022; F:protein C-terminus binding; IPI:RGD; .
GOGO:0046982; F:protein heterodimerization activity; IPI:RGD; .
GOGO:0045807; P:positive regulation of endocytosis; IMP:RGD; .
GOGO:0043547; P:positive regulation of GTPase activity; IDA:RGD; .
InterProIPR003005; Amphiphysin; .
InterProIPR003017; Amphiphysin_1; .
InterProIPR004148; BAR; .
InterProIPR011511; SH3_2; .
InterProIPR001452; SH3_domain; .
KOK12562; -; .
PfamPF03114; BAR; 1; .
PfamPF07653; SH3_2; 1; .
SMARTSM00721; BAR; 1; .
SMARTSM00326; SH3; 1; .
SUPFAMSSF50044; SH3; 1; .
PROSITEPS51021; BAR; 1; .
PROSITEPS50002; SH3; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server