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World-2DPAGE Repository
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Searching in 'World-2DPAGE Repository [0004]' for entry
matching:
O35244
World-2DPAGE Repository
(0004):
O35244
O35244
General information about the entry
View entry in simple text format
Entry name
PRDX6_RAT
Primary accession number
O35244
integrated into World-2DPAGE Repository (0004) on
October 13, 2008 (release 1)
2D Annotations were last modified on
May 18, 2011 (version 2)
General Annotations were last modified on
December 22, 2011 (version 2)
Name and origin of the protein
Description
RecName: Full=Peroxiredoxin-6; EC=1.11.1.15; AltName: Full=1-Cys peroxiredoxin; Short=1-Cys PRX; AltName: Full=Acidic calcium-independent phospholipase A2; Short=aiPLA2; EC=3.1.1.-; AltName: Full=Antioxidant protein 2; AltName: Full=Non-selenium glutathione peroxidase; Short=NSGPx; EC=1.11.1.9; AltName: Full=Thiol-specific antioxidant protein;.
Gene name
Name=Prdx6
Synonyms=Aipla2, Aop2, Tsa
Annotated species
Rattus norvegicus (Rat) [TaxID:
10116
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]
MAPPING ON GEL
PubMed=19343716; DOI=
10.1002/pmic.200800664
; [
NCBI
,
EBI
,
Israel
,
Japan
]
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of the mature rat olfactory bulb''
Proteomics 9(1):2593-2599 (2009)
2D PAGE maps for identified proteins
How to interpret a protein
OB21DSUB
{2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb
map experimental info
OB21DSUB
MAP LOCATIONS:
SPOT 656
:
pI=5.72; Mw=25000
[identification data]
MAPPING (identification):
SPOT
656
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
].
Copyright
Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
Cross-references
UniProtKB/Swiss-Prot
O35244; PRDX6_RAT.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
2011_12
Entry name
PRDX6_RAT
Primary accession number
O35244
Sequence was last modified on
January 23, 2007 (version 3)
Annotations were last modified on
November 16, 2011 (version 101)
Name and origin of the protein
Description
RecName: Full=Peroxiredoxin-6; EC=1.11.1.15; AltName: Full=1-Cys peroxiredoxin; Short=1-Cys PRX; AltName: Full=Acidic calcium-independent phospholipase A2; Short=aiPLA2; EC=3.1.1.-; AltName: Full=Antioxidant protein 2; AltName: Full=Non-selenium glutathione peroxidase; Short=NSGPx; EC=1.11.1.9; AltName: Full=Thiol-specific antioxidant protein;
Gene name
Name=Prdx6
Synonyms=Aipla2, Aop2, Tsa
Encoded on
Name=Prdx6; Synonyms=Aipla2, Aop2, Tsa
Keywords
Acetylation
;
Antioxidant
;
Complete proteome
;
Cytoplasm
;
Cytoplasmic vesicle
;
Direct protein sequencing
;
Disulfide bond
;
Hydrolase
;
Lipid degradation
;
Lysosome
;
Multifunctional enzyme
;
Oxidoreductase
;
Peroxidase
;
Phosphoprotein
;
Redox-active center
;
Reference proteome
.
Copyright
Copyrighted by the UniProt Consortium, see
https://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
AF014009; AAB66341.1
; -; mRNA
EMBL
Y17295; CAA76732.1
; -; mRNA
IPI
IPI00231260; -
; .
RefSeq
NP_446028.1; NM_053576.2
; .
UniGene
Rn.42; -
; .
ProteinModelPortal
O35244; -
; .
SMR
O35244; 5-224
; .
IntAct
O35244; 1
; .
STRING
O35244; -
; .
PeroxiBase
4427; Rno1CysPrx
; .
PhosphoSite
O35244; -
; .
World-2DPAGE
0004:O35244; -
; .
PRIDE
O35244; -
; .
Ensembl
ENSRNOT00000034583; ENSRNOP00000030323
; ENSRNOG00000002896; .
GeneID
94167; -
; .
KEGG
rno:94167; -
; .
UCSC
NM_053576; rat
; .
CTD
9588; -
; .
RGD
71005; Prdx6
; .
eggNOG
roNOG13330; -
; .
GeneTree
ENSGT00550000074794; -
; .
HOVERGEN
HBG105234; -
; .
InParanoid
O35244; -
; .
OMA
NYPILAD; -
; .
OrthoDB
EOG4M399H; -
; .
PhylomeDB
O35244; -
; .
BRENDA
1.11.1.15; 5301
; .
NextBio
617808; -
; .
ArrayExpress
O35244; -
; .
Genevestigator
O35244; -
; .
GermOnline
ENSRNOG00000002896; Rattus norvegicus
; .
GO
GO:0016023; C:cytoplasmic membrane-bounded vesicle
; IEA:UniProtKB-SubCell; .
GO
GO:0005764; C:lysosome
; IEA:UniProtKB-SubCell; .
GO
GO:0004602; F:glutathione peroxidase activity
; IDA:RGD; .
GO
GO:0051920; F:peroxiredoxin activity
; IEA:EC; .
GO
GO:0005515; F:protein binding
; IPI:RGD; .
GO
GO:0042744; P:hydrogen peroxide catabolic process
; IDA:RGD; .
InterPro
IPR000866; AhpC/TSA
; .
InterPro
IPR024706; Peroxiredoxin_AhpC-typ
; .
InterPro
IPR019479; Peroxiredoxin_C
; .
InterPro
IPR012336; Thioredoxin-like_fold
; .
Gene3D
G3DSA:3.40.30.10; Thioredoxin_fold
; 1; .
KO
K11188; -
; .
Pfam
PF10417; 1-cysPrx_C
; 1; .
Pfam
PF00578; AhpC-TSA
; 1; .
PIRSF
PIRSF000239; AHPC
; 1; .
SUPFAM
SSF52833; Thiordxn-like_fd
; 1; .
PROSITE
PS51352; THIOREDOXIN_2
; 1; .
World-2DPAGE Repository (search AC)
Database constructed and maintained by
SIB
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
Expasy web server