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Searching in 'World-2DPAGE Repository [0027]' for entry matching: O35737

World-2DPAGE Repository (0027):  O35737


General information about the entry
View entry in simple text format
Entry nameHNRH1_MOUSE
Primary accession numberO35737
integrated into World-2DPAGE Repository (0027) on September 30, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Heterogeneous nuclear ribonucleoprotein H; Short=hnRNP H; Contains: RecName: Full=Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;.
Gene nameName=Hnrnph1
Synonyms=Hnrph, Hnrph1
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
Blutke A., Block C., Berendt F., Herbach N., Kemter E., Amann K., Frolich T., Arnold G.J., Wanke R.
''Differential glomerular proteome analysis of two murine nephropathy models at onset of albuminuria''
Proteomics - Clinical Applications 5(6):375-381 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

GIPRDN_4-7 {glomerular protein lysates of a GIPRdn-tg animal}
Mus musculus (Mouse)
  map experimental info

pI=5.92; Mw=51000  [identification data]
pI=6.51; Mw=23000  [identification data]

SPOT 11: Avg ratio GIPRdn-tg vs. control=-1.54 (p-value=0.0072) [1];
SPOT 29: Avg ratio GIPRdn-tg vs. control=5.88 (p-value=0.0044) [1].

IDENTIFICATION: SPOT 11: SeqCov=37%. Mascot protein score=287 [1]
SPOT 29: SeqCov=14%. Mascot protein score=178 [1].
MAPPING (identification):
SPOT 11: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 29: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Data from Dr. Andreas Blutke, Institute of Veterinary Pathology, University Munich, Germany
UniProtKB/Swiss-ProtO35737; HNRH1_MOUSE.
World-2DPAGE RepositoryO35737; HNRH1_MOUSE.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameHNRH1_MOUSE
Primary accession numberO35737
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on November 16, 2011 (version 104)
Name and origin of the protein
DescriptionRecName: Full=Heterogeneous nuclear ribonucleoprotein H; Short=hnRNP H; Contains: RecName: Full=Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;
Gene nameName=Hnrnph1
Synonyms=Hnrph, Hnrph1
Encoded onName=Hnrnph1; Synonyms=Hnrph, Hnrph1
KeywordsAcetylation; Complete proteome; Direct protein sequencing; Methylation; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Repeat; Ribonucleoprotein; RNA-binding; Spliceosome.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLY14196; CAA74583.1; -; mRNA
EMBLBC056224; AAH56224.1; -; mRNA
IPIIPI00133916; -; .
RefSeqNP_067485.1; NM_021510.2; .
UniGeneMm.21740; -; .
ProteinModelPortalO35737; -; .
SMRO35737; 1-102; 105-193; 283-365
IntActO35737; 8; .
STRINGO35737; -; .
PhosphoSiteO35737; -; .
PRIDEO35737; -; .
EnsemblENSMUST00000069304; ENSMUSP00000070503; ENSMUSG00000007850; .
EnsemblENSMUST00000109142; ENSMUSP00000104770; ENSMUSG00000007850; .
GeneID59013; -; .
KEGGmmu:59013; -; .
CTD3187; -; .
MGIMGI:1891925; Hnrnph1; .
eggNOGroNOG06834; -; .
HOVERGENHBG055557; -; .
OrthoDBEOG4CRM03; -; .
NextBio314564; -; .
ArrayExpressO35737; -; .
BgeeO35737; -; .
GenevestigatorO35737; -; .
GermOnlineENSMUSG00000007850; Mus musculus; .
GOGO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell; .
GOGO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW; .
GOGO:0000166; F:nucleotide binding; IEA:InterPro; .
GOGO:0003723; F:RNA binding; ISS:UniProtKB; .
GOGO:0006397; P:mRNA processing; IEA:UniProtKB-KW; .
GOGO:0043484; P:regulation of RNA splicing; ISS:UniProtKB; .
GOGO:0008380; P:RNA splicing; IEA:UniProtKB-KW; .
InterProIPR012677; Nucleotide-bd_a/b_plait; .
InterProIPR000504; RRM_dom; .
InterProIPR012996; Znf_CHHC; .
Gene3DG3DSA:; a_b_plait_nuc_bd; 3; .
KOK12898; -; .
PfamPF00076; RRM_1; 3; .
PfamPF08080; zf-RNPHF; 1; .
SMARTSM00360; RRM; 3; .
PROSITEPS50102; RRM; 3; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server