Attention: World-2DPAGE is no longer maintained.

World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0022]' for entry matching: O88483 World-2DPAGE Repository (0022):  O88483 O88483 General information about the entry View entry in simple text format Entry name PDP1_RAT Primary accession number O88483 integrated into World-2DPAGE Repository (0022) on  May 7, 2010 (release 1) 2D Annotations were last modified on June 22, 2011 (version 2) General Annotations were last modified on  November 24, 2011 (version 2) Name and origin of the protein Description RecName: Full=[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial; Short=PDP 1; EC=3.1.3.43; AltName: Full=Protein phosphatase 2C; AltName: Full=Pyruvate dehydrogenase phosphatase catalytic subunit 1; Short=PDPC 1; Flags: Precursor;. Gene name Name=Pdp1 Synonyms=Ppm2c Annotated species Rattus [TaxID: 10114] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000593; Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L. ''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity'' Proteomics 11(16):3369-3379 (2011) 2D PAGE maps for identified proteins How to interpret a protein HCR_LCR_HEART {HCR LCR Cardiac Map} Rattus Tissue: Heart   map experimental info   HCR_LCR_HEART MAP LOCATIONS: SPOT 200: pI=6.34; Mw=61739   [identification data] IDENTIFICATION: SPOT 200: SeqCov=30.1%. Peptides MS=12/20. Mascot PMF Score=95 [1]. PEPTIDE EVIDENCE: SPOT 200: 485-HAVGNNEFGAVDHER-499 (94) / 384-FIPPNYHTPPYLTAEPEVTYHR-405 (88) [1]. MAPPING (identification): SPOT 200: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Jatin Burniston, Liverpool John Moores University, UK Cross-references UniProtKB/Swiss-Prot O88483; PDP1_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name PDP1_RAT Primary accession number O88483 Sequence was last modified on  November 1, 1998 (version 1) Annotations were last modified on  October 19, 2011 (version 92) Name and origin of the protein Description RecName: Full=[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial; Short=PDP 1; EC=3.1.3.43; AltName: Full=Protein phosphatase 2C; AltName: Full=Pyruvate dehydrogenase phosphatase catalytic subunit 1; Short=PDPC 1; Flags: Precursor; Gene name Name=Pdp1 Synonyms=Ppm2c Encoded on Name=Pdp1; Synonyms=Ppm2c Keywords 3D-structure; Acetylation; Calcium; Complete proteome; Hydrolase; Magnesium; Metal-binding; Mitochondrion; Protein phosphatase; Reference proteome; Transit peptide. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF062740; AAC40167.1; -; mRNA IPI IPI00209752; -; . UniGene Rn.31799; -; . PDB 2PNQ; X-ray; 1.81 A; A/B=72-538 PDBsum 2PNQ; -; . ProteinModelPortal O88483; -; . SMR O88483; 80-538; . STRING O88483; -; . PhosphoSite O88483; -; . PRIDE O88483; -; . UCSC NM_019372; rat; . RGD 620393; Pdp1; . GeneTree ENSGT00390000006874; -; . HOVERGEN HBG008162; -; . InParanoid O88483; -; . OrthoDB EOG4XD3QP; -; . PhylomeDB O88483; -; . BRENDA 3.1.3.43; 5301; . ArrayExpress O88483; -; . Genevestigator O88483; -; . GermOnline ENSRNOG00000016180; Rattus norvegicus; . GO GO:0005759; C:mitochondrial matrix; TAS:RGD; . GO GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro; . GO GO:0004741; F:[pyruvate dehydrogenase (lipoamide)] phosphatase activity; IDA:RGD; . GO GO:0005509; F:calcium ion binding; ISS:UniProtKB; . GO GO:0000287; F:magnesium ion binding; IDA:RGD; . GO GO:0004724; F:magnesium-dependent protein serine/threonine phosphatase activity; IDA:RGD; . GO GO:0032403; F:protein complex binding; IMP:RGD; . GO GO:0043085; P:positive regulation of catalytic activity; IC:RGD; . GO GO:0006470; P:protein dephosphorylation; IDA:RGD; . InterPro IPR001932; PP2C-like; . InterPro IPR000222; PP2C_Mn2_Asp60_BS; . InterPro IPR015655; Protein_Pase_2C; . Gene3D G3DSA:3.60.40.10; PP2C-related; 3; . PANTHER PTHR13832; PP2C; 1; . Pfam PF00481; PP2C; 1; . SMART SM00331; PP2C_SIG; 1; . SMART SM00332; PP2Cc; 1; . SUPFAM SSF81606; PP2C-related; 1; . PROSITE PS01032; PP2C; 1; . World-2DPAGE Repository (search AC)