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Searching in 'World-2DPAGE Repository [0030]' for entry matching: O88600

World-2DPAGE Repository (0030):  O88600


General information about the entry
View entry in simple text format
Entry nameHSP74_RAT
Primary accession numberO88600
integrated into World-2DPAGE Repository (0030) on November 9, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Heat shock 70 kDa protein 4; AltName: Full=Ischemia responsive 94 kDa protein;.
Gene nameName=Hspa4
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C.
''Two-dimensional gel proteome reference map of INS-1E cells''
Proteomics 11(7):1365-1369 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7}
Rattus norvegicus (Rat)
  map experimental info

pI=5.04; Mw=97871  [identification data]
pI=5.08; Mw=97736  [identification data]
pI=5.13; Mw=97736  [identification data]
pI=5.11; Mw=97601  [identification data]

IDENTIFICATION: SPOT 205: Mascot protein score=389. Number of peptides=11 [1]
SPOT 208: Mascot protein score=72. Number of peptides=6 [1]; SPOT 210: Mascot protein score=230. Number of peptides=7 [1]; SPOT 211: Mascot protein score=203. Number of peptides=10 [1].
MAPPING (identification):
SPOT 205: Tandem mass spectrometry [1];
SPOT 208: Tandem mass spectrometry [1];
SPOT 210: Tandem mass spectrometry [1];
SPOT 211: Tandem mass spectrometry [1].

Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium
UniProtKB/Swiss-ProtO88600; HSP74_RAT.
World-2DPAGE RepositoryO88600; HSP74_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameHSP74_RAT
Primary accession numberO88600
Sequence was last modified on November 1, 1998 (version 1)
Annotations were last modified on November 16, 2011 (version 80)
Name and origin of the protein
DescriptionRecName: Full=Heat shock 70 kDa protein 4; AltName: Full=Ischemia responsive 94 kDa protein;
Gene nameName=Hspa4
Encoded onName=Hspa4; Synonyms=Irp94
KeywordsAcetylation; ATP-binding; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleotide-binding; Phosphoprotein; Reference proteome; Stress response.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLAF077354; AAC27937.1; -; mRNA
IPIIPI00387868; -; .
RefSeqNP_705893.1; NM_153629.1; .
UniGeneRn.163092; -; .
HSSPP19120; 1BA1; .
ProteinModelPortalO88600; -; .
MINTMINT-4566747; -; .
STRINGO88600; -; .
PhosphoSiteO88600; -; .
World-2DPAGE0004:O88600; -; .
PRIDEO88600; -; .
GeneID266759; -; .
KEGGrno:266759; -; .
UCSCNM_153629; rat; .
CTD3308; -; .
RGD628878; Hspa4; .
eggNOGmaNOG07919; -; .
GeneTreeENSGT00390000016919; -; .
HOVERGENHBG047955; -; .
InParanoidO88600; -; .
OrthoDBEOG415GCS; -; .
PhylomeDBO88600; -; .
NextBio624599; -; .
ArrayExpressO88600; -; .
GenevestigatorO88600; -; .
GermOnlineENSRNOG00000016596; Rattus norvegicus; .
GOGO:0005829; C:cytosol; IDA:RGD; .
GOGO:0005811; C:lipid particle; IDA:RGD; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0032092; P:positive regulation of protein binding; IDA:RGD; .
GOGO:0009408; P:response to heat; IDA:RGD; .
InterProIPR018181; Heat_shock_70_CS; .
InterProIPR001023; Hsp70; .
InterProIPR013126; Hsp_70; .
KOK09489; -; .
PANTHERPTHR19375; Hsp70; 1; .
PfamPF00012; HSP70; 2; .
PROSITEPS00329; HSP70_2; 1; .
PROSITEPS01036; HSP70_3; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server