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Searching in 'World-2DPAGE Repository [0019]' for entry matching: ODO2_RAT




World-2DPAGE Repository (0019):  ODO2_RAT

ODO2_RAT


General information about the entry
View entry in simple text format
Entry nameODO2_RAT
Primary accession numberQ01205
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial; EC=2.3.1.61; AltName: Full=2-oxoglutarate dehydrogenase complex component E2; Short=OGDC-E2; AltName: Full=Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; AltName: Full=E2K; Flags: Precursor;.
Gene nameName=Dlst
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1111/j.1471-4159.2010.06719.x;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
HIPP_SYNAP
  map experimental info 		 
HIPP_SYNAP

MAP LOCATIONS:
pI=8.89; Mw=49236  [identification data]
pI=8.89; Mw=49236  [identification data]

IDENTIFICATION: SPOT 434: Peptides number=6. SeqCov=16.5%. MOWSE score=8.82E+4 [1]
SPOT 996: Peptides number=8. SeqCov=21.6%. MOWSE score=2.11E+5 [1].
MAPPING (identification):
SPOT 434: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 996: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-ProtQ01205; ODO2_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameODO2_RAT
Primary accession numberQ01205
Secondary accession number(s) Q5XI35
Sequence was last modified on April 12, 2005 (version 2)
Annotations were last modified on November 16, 2011 (version 108)
Name and origin of the protein
DescriptionRecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial; EC=2.3.1.61; AltName: Full=2-oxoglutarate dehydrogenase complex component E2; Short=OGDC-E2; AltName: Full=Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; AltName: Full=E2K; Flags: Precursor;
Gene nameName=Dlst
Encoded onName=Dlst
KeywordsAcetylation; Acyltransferase; Complete proteome; Direct protein sequencing; Lipoyl; Mitochondrion; Reference proteome; Transferase; Transit peptide; Tricarboxylic acid cycle.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLBC083858; AAH83858.1; -; mRNA
EMBLD90401; BAA14397.1; -; mRNA
IPIIPI00551702; -; .
PIRA41015; A41015; .
RefSeqNP_001006982.2; NM_001006981.2; .
UniGeneRn.99702; -; .
ProteinModelPortalQ01205; -; .
SMRQ01205; 221-454; .
IntActQ01205; 1; .
STRINGQ01205; -; .
PhosphoSiteQ01205; -; .
GeneID299201; -; .
KEGGrno:299201; -; .
UCSCNM_001006981; rat; .
CTD1743; -; .
RGD1359615; Dlst; .
eggNOGmaNOG14055; -; .
HOVERGENHBG000268; -; .
InParanoidQ01205; -; .
OrthoDBEOG4B2SZ1; -; .
PhylomeDBQ01205; -; .
BRENDA2.3.1.61; 5301; .
NextBio644993; -; .
ArrayExpressQ01205; -; .
GenevestigatorQ01205; -; .
GermOnlineENSRNOG00000005061; Rattus norvegicus; .
GOGO:0005792; C:microsome; IDA:RGD; .
GOGO:0005739; C:mitochondrion; IDA:RGD; .
GOGO:0045252; C:oxoglutarate dehydrogenase complex; IDA:RGD; .
GOGO:0005886; C:plasma membrane; IDA:RGD; .
GOGO:0051087; F:chaperone binding; IPI:RGD; .
GOGO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IDA:RGD; .
GOGO:0031072; F:heat shock protein binding; IPI:RGD; .
GOGO:0006103; P:2-oxoglutarate metabolic process; IDA:RGD; .
GOGO:0006734; P:NADH metabolic process; IDA:RGD; .
GOGO:0006099; P:tricarboxylic acid cycle; IC:RGD; .
InterProIPR003016; 2-oxoA_DH_lipoyl-BS; .
InterProIPR001078; 2-oxoacid_DH_actylTfrase; .
InterProIPR000089; Biotin_lipoyl; .
InterProIPR023213; CAT-like_dom; .
InterProIPR011053; Single_hybrid_motif; .
InterProIPR006255; SucB; .
Gene3DG3DSA:3.30.559.10; CAT-like_dom; 1; .
KOK00658; -; .
PfamPF00198; 2-oxoacid_dh; 1; .
PfamPF00364; Biotin_lipoyl; 1; .
SUPFAMSSF51230; Hybrid_motif; 1; .
TIGRFAMsTIGR01347; SucB; 1; .
PROSITEPS50968; BIOTINYL_LIPOYL; 1; .
PROSITEPS00189; LIPOYL; 1; .


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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server