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Searching in 'World-2DPAGE Repository [0022]' for entry matching: P02770




World-2DPAGE Repository (0022):  P02770


P02770


General information about the entry
View entry in simple text format
Entry nameALBU_RAT
Primary accession numberP02770
integrated into World-2DPAGE Repository (0022) on May 7, 2010 (release 1)
2D Annotations were last modified onJune 22, 2011 (version 2)
General Annotations were last modified on November 24, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Serum albumin; Flags: Precursor;.
Gene nameName=Alb
Annotated speciesRattus [TaxID: 10114]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/pmic.201000593;
Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L.
''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity''
Proteomics 11(16):3369-3379 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

HCR_LCR_HEART {HCR LCR Cardiac Map}
Rattus
Tissue: Heart
HCR_LCR_HEART
  map experimental info
 
HCR_LCR_HEART

MAP LOCATIONS:
pI=6.09; Mw=70682  [identification data]
pI=6.09; Mw=70682  [identification data]
pI=6.09; Mw=70682  [identification data]
pI=6.09; Mw=70682  [identification data]

IDENTIFICATION: SPOT 238: SeqCov=28.9%. Peptides MS=14/20. Mascot PMF Score=130 [1]
SPOT 259: SeqCov=18.9%. Peptides MS=8/20. Mascot PMF Score=55 [1]; SPOT 290: SeqCov=35.5%. Peptides MS=17/20. Mascot PMF Score=181 [1]; SPOT 759: SeqCov=21.2%. Peptides MS=9/20. Mascot PMF Score=67 [1].
PEPTIDE EVIDENCE: SPOT 259: 45-GLVLIAFSQYLQK-57 (6) / 348-DVFLGTFLYEYSR-360 (81) / 169-RHPYFYAPELLYYAEK-184 (103) [1]
SPOT 759: 348-DVFLGTFLYEYSR-360 (122) / 169-RHPYFYAPELLYYAEK-184 (114) [1].
MAPPING (identification):
SPOT 238: Peptide mass fingerprinting [1];
SPOT 259: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 290: Peptide mass fingerprinting [1];
SPOT 759: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Jatin Burniston, Liverpool John Moores University, UK
Cross-references
UniProtKB/Swiss-ProtP02770; ALBU_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameALBU_RAT
Primary accession numberP02770
Secondary accession number(s) P11382 Q5U3X3
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on November 16, 2011 (version 114)
Name and origin of the protein
DescriptionRecName: Full=Serum albumin; Flags: Precursor;
Gene nameName=Alb
Encoded onName=Alb
KeywordsCleavage on pair of basic residues; Complete proteome; Copper; Direct protein sequencing; Disulfide bond; Lipid-binding; Metal-binding; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Secreted; Signal; Zinc.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLV01222; CAA24532.1; -; mRNA
EMBLBC085359; AAH85359.1; -; mRNA
IPIIPI00191737; -; .
PIRA93872; ABRTS; .
RefSeqNP_599153.2; NM_134326.2; .
UniGeneRn.202968; -; .
ProteinModelPortalP02770; -; .
SMRP02770; 26-608; .
IntActP02770; 2; .
STRINGP02770; -; .
Allergome756; Rat n RSA; .
PhosphoSiteP02770; -; .
Rat-heart-2DPAGEP02770; -; .
UCD-2DPAGEP02770; -; .
World-2DPAGE0004:P02770; -; .
PRIDEP02770; -; .
EnsemblENSRNOT00000003921; ENSRNOP00000003921; ENSRNOG00000002911; .
GeneID24186; -; .
KEGGrno:24186; -; .
UCSCNM_134326; rat; .
CTD213; -; .
RGD2085; Alb; .
eggNOGroNOG13173; -; .
GeneTreeENSGT00390000000113; -; .
HOVERGENHBG004207; -; .
InParanoidP02770; -; .
OrthoDBEOG4Z0B55; -; .
NextBio602549; -; .
ArrayExpressP02770; -; .
GenevestigatorP02770; -; .
GermOnlineENSRNOG00000002911; Rattus norvegicus; .
GOGO:0005604; C:basement membrane; IDA:RGD; .
GOGO:0005615; C:extracellular space; IDA:RGD; .
GOGO:0043234; C:protein complex; ISS:UniProtKB; .
GOGO:0043498; F:cell surface binding; IDA:RGD; .
GOGO:0003677; F:DNA binding; ISS:UniProtKB; .
GOGO:0008144; F:drug binding; ISS:UniProtKB; .
GOGO:0019899; F:enzyme binding; IPI:RGD; .
GOGO:0005504; F:fatty acid binding; ISS:UniProtKB; .
GOGO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB; .
GOGO:0015643; F:toxin binding; ISS:UniProtKB; .
GOGO:0008270; F:zinc ion binding; IDA:RGD; .
GOGO:0009267; P:cellular response to starvation; ISS:UniProtKB; .
GOGO:0019836; P:hemolysis by symbiont of host erythrocytes; ISS:UniProtKB; .
GOGO:0051659; P:maintenance of mitochondrion location; ISS:UniProtKB; .
GOGO:0043066; P:negative regulation of apoptosis; ISS:UniProtKB; .
GOGO:0046010; P:positive regulation of circadian sleep/wake cycle; non-REM sleep; IDA:RGD
GOGO:0046689; P:response to mercury ion; IEP:RGD; .
GOGO:0007584; P:response to nutrient; IEP:RGD; .
GOGO:0010033; P:response to organic substance; IEP:RGD; .
GOGO:0070541; P:response to platinum ion; IEP:RGD; .
GOGO:0006810; P:transport; IEA:InterPro; .
GOGO:0042311; P:vasodilation; NAS:RGD; .
InterProIPR000264; Serum_albumin; .
InterProIPR020858; Serum_albumin-like; .
InterProIPR020857; Serum_albumin_CS; .
InterProIPR014760; Serum_albumin_N; .
InterProIPR021177; Serum_albumin_subgr; .
PfamPF00273; Serum_albumin; 3; .
PIRSFPIRSF002520; Serum_albumin_subgroup; 1; .
PRINTSPR00802; SERUMALBUMIN; .
SMARTSM00103; ALBUMIN; 3; .
SUPFAMSSF48552; Serum_albumin; 3; .
PROSITEPS00212; ALBUMIN_1; 3; .
PROSITEPS51438; ALBUMIN_2; 3; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server