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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0022]' for entry matching: P04041 World-2DPAGE Repository (0022):  P04041 P04041 General information about the entry View entry in simple text format Entry name GPX1_RAT Primary accession number P04041 integrated into World-2DPAGE Repository (0022) on  May 7, 2010 (release 1) 2D Annotations were last modified on June 22, 2011 (version 2) General Annotations were last modified on  November 24, 2011 (version 2) Name and origin of the protein Description RecName: Full=Glutathione peroxidase 1; Short=GPx-1; Short=GSHPx-1; EC=1.11.1.9; AltName: Full=Cellular glutathione peroxidase;. Gene name Name=Gpx1 Annotated species Rattus [TaxID: 10114] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000593; Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L. ''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity'' Proteomics 11(16):3369-3379 (2011) 2D PAGE maps for identified proteins How to interpret a protein HCR_LCR_HEART {HCR LCR Cardiac Map} Rattus Tissue: Heart   map experimental info   HCR_LCR_HEART MAP LOCATIONS: SPOT 712: pI=7.70; Mw=22463   [identification data] IDENTIFICATION: SPOT 712: SeqCov=23.4%. Peptides MS=5/20. Mascot PMF Score=44 [1]. PEPTIDE EVIDENCE: SPOT 712: 120-AHPLFTFLR-128 (60) / 147-YIIWSPVCR-155 (56) / 96-YVRPGGGFEPNFTLFEK-112 (11) [1]. MAPPING (identification): SPOT 712: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Jatin Burniston, Liverpool John Moores University, UK Cross-references UniProtKB/Swiss-Prot P04041; GPX1_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name GPX1_RAT Primary accession number P04041 Secondary accession number(s) O08946 Q4PIY2 Q91WZ5 Sequence was last modified on  February 26, 2008 (version 4) Annotations were last modified on  November 16, 2011 (version 106) Name and origin of the protein Description RecName: Full=Glutathione peroxidase 1; Short=GPx-1; Short=GSHPx-1; EC=1.11.1.9; AltName: Full=Cellular glutathione peroxidase; Gene name Name=Gpx1 Encoded on Name=Gpx1 Keywords Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Oxidoreductase; Peroxidase; Reference proteome; Selenocysteine. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M21210; AAB95647.2; -; mRNA EMBL X07365; CAB43593.1; -; mRNA EMBL X12367; CAA30928.2; -; mRNA EMBL S50336; AAA12407.2; -; Genomic_DNA EMBL S41066; AAK72702.1; -; mRNA EMBL AB004231; BAA20399.2; -; Genomic_DNA IPI IPI00192301; -; . PIR A30793; OPRTE; . RefSeq NP_110453.3; NM_030826.3; . UniGene Rn.11323; -; . ProteinModelPortal P04041; -; . PeroxiBase 3730; RnoGPx01; . PRIDE P04041; -; . GeneID 24404; -; . KEGG rno:24404; -; . UCSC BC058438; rat; . CTD 2876; -; . RGD 2729; Gpx1; . eggNOG maNOG16607; -; . HOVERGEN HBG004333; -; . NextBio 603207; -; . Genevestigator P04041; -; . GO GO:0005829; C:cytosol; TAS:RGD; . GO GO:0005634; C:nucleus; IDA:RGD; . GO GO:0005625; C:soluble fraction; IDA:RGD; . GO GO:0043295; F:glutathione binding; IDA:RGD; . GO GO:0004602; F:glutathione peroxidase activity; IDA:RGD; . GO GO:0047066; F:phospholipid-hydroperoxide glutathione peroxidase activity; IMP:RGD; . GO GO:0008430; F:selenium binding; IMP:RGD; . GO GO:0007568; P:aging; IEP:RGD; . GO GO:0006749; P:glutathione metabolic process; IDA:RGD; . GO GO:0042744; P:hydrogen peroxide catabolic process; IDA:RGD; . GO GO:0032355; P:response to estradiol stimulus; IEP:RGD; . GO GO:0051593; P:response to folic acid; IEP:RGD; . GO GO:0009749; P:response to glucose stimulus; IEP:RGD; . GO GO:0006982; P:response to lipid hydroperoxide; IMP:RGD; . GO GO:0035094; P:response to nicotine; IEP:RGD; . GO GO:0010269; P:response to selenium ion; IEP:RGD; . InterPro IPR000889; Glutathione_peroxidase; . InterPro IPR012336; Thioredoxin-like_fold; . Gene3D G3DSA:3.40.30.10; Thioredoxin_fold; 1; . KO K00432; -; . PANTHER PTHR11592; Glut_peroxidase; 1; . Pfam PF00255; GSHPx; 1; . PIRSF PIRSF000303; Glutathion_perox; 1; . PRINTS PR01011; GLUTPROXDASE; . SUPFAM SSF52833; Thiordxn-like_fd; 1; . PROSITE PS00460; GLUTATHIONE_PEROXID_1; 1; . PROSITE PS00763; GLUTATHIONE_PEROXID_2; 1; . PROSITE PS51355; GLUTATHIONE_PEROXID_3; 1; . World-2DPAGE Repository (search AC)