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World-2DPAGE Repository
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Searching in 'World-2DPAGE Repository [0022]' for entry
matching:
P04639
World-2DPAGE Repository
(0022):
P04639
P04639
General information about the entry
View entry in simple text format
Entry name
APOA1_RAT
Primary accession number
P04639
integrated into World-2DPAGE Repository (0022) on
May 7, 2010 (release 1)
2D Annotations were last modified on
June 22, 2011 (version 2)
General Annotations were last modified on
November 24, 2011 (version 2)
Name and origin of the protein
Description
RecName: Full=Apolipoprotein A-I; Short=Apo-AI; Short=ApoA-I; AltName: Full=Apolipoprotein A1; Flags: Precursor;.
Gene name
Name=Apoa1
Annotated species
Rattus [TaxID:
10114
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae.
References
[1]
2D-PAGE GEL CHARACTERIZATION
DOI=
10.1002/pmic.201000593
;
Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L.
''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity''
Proteomics 11(16):3369-3379 (2011)
2D PAGE maps for identified proteins
How to interpret a protein
HCR_LCR_HEART
{HCR LCR Cardiac Map}
Rattus
Tissue: Heart
map experimental info
HCR_LCR_HEART
MAP LOCATIONS:
SPOT 443
:
pI=5.52; Mw=30100
[identification data]
IDENTIFICATION:
SPOT 443: SeqCov=29.7%. Peptides MS=9/20. Mascot PMF Score=55 [
1
].
PEPTIDE EVIDENCE:
SPOT 443: 162-VVAEEFR-168 (34): 131-WNEEVEAYR-139 (75): 64-QLNLNLLDNWDTLGSTVGR-82 (15) [
1
].
MAPPING (identification):
SPOT
443
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
].
Copyright
Data from Dr. Jatin Burniston, Liverpool John Moores University, UK
Cross-references
UniProtKB/Swiss-Prot
P04639; APOA1_RAT.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
2011_11
Entry name
APOA1_RAT
Primary accession number
P04639
Secondary accession number(s)
O08877 O09054 Q5EBB2
Sequence was last modified on
May 1, 2007 (version 2)
Annotations were last modified on
November 16, 2011 (version 87)
Name and origin of the protein
Description
RecName: Full=Apolipoprotein A-I; Short=Apo-AI; Short=ApoA-I; AltName: Full=Apolipoprotein A1; Flags: Precursor;
Gene name
Name=Apoa1
Encoded on
Name=Apoa1
Keywords
Cholesterol metabolism
;
Complete proteome
;
Direct protein sequencing
;
HDL
;
Lipid metabolism
;
Lipid transport
;
Phosphoprotein
;
Reference proteome
;
Repeat
;
Secreted
;
Signal
;
Steroid metabolism
;
Transport
.
Copyright
Copyrighted by the UniProt Consortium, see
https://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
M00001; AAA40749.1
; -; mRNA
EMBL
X00558; CAA25224.1
; -; mRNA
EMBL
J02597; AAA40745.1
; -; Genomic_DNA
EMBL
U79576; AAB58428.1
; -; Genomic_DNA
EMBL
U79577; AAB58429.1
; -; Genomic_DNA
EMBL
U79578; AAB58430.1
; -; Genomic_DNA
EMBL
BC089820; AAH89820.1
; -; mRNA
IPI
IPI00197703; -
; .
PIR
A24700; A24700
; .
RefSeq
NP_036870.1; NM_012738.1
; .
UniGene
Rn.10308; -
; .
ProteinModelPortal
P04639; -
; .
SMR
P04639; 25-258
; .
DIP
DIP-29911N; -
; .
IntAct
P04639; 1
; .
PRIDE
P04639; -
; .
GeneID
25081; -
; .
KEGG
rno:25081; -
; .
CTD
335; -
; .
RGD
2130; Apoa1
; .
HOVERGEN
HBG105708; -
; .
NextBio
605334; -
; .
Genevestigator
P04639; -
; .
GO
GO:0034364; C:high-density lipoprotein particle
; IEA:UniProtKB-KW; .
GO
GO:0005634; C:nucleus
; IDA:RGD; .
GO
GO:0017127; F:cholesterol transporter activity
; IDA:RGD; .
GO
GO:0055102; F:lipase inhibitor activity
; IDA:RGD; .
GO
GO:0008289; F:lipid binding
; IEA:InterPro; .
GO
GO:0005548; F:phospholipid transporter activity
; IDA:RGD; .
GO
GO:0008203; P:cholesterol metabolic process
; IEA:UniProtKB-KW; .
GO
GO:0042157; P:lipoprotein metabolic process
; IEA:InterPro; .
GO
GO:0060192; P:negative regulation of lipase activity
; IDA:RGD; .
GO
GO:0031100; P:organ regeneration
; IDA:RGD; .
GO
GO:0014012; P:peripheral nervous system axon regeneration
; IEP:RGD; .
GO
GO:0042493; P:response to drug
; IEP:RGD; .
GO
GO:0043627; P:response to estrogen stimulus
; IEP:RGD; .
GO
GO:0007584; P:response to nutrient
; IEP:RGD; .
InterPro
IPR013326; ApoA/E_ApoLp
; .
InterPro
IPR000074; ApoA1_A4_E
; .
Gene3D
G3DSA:1.20.120.20; ApoA/E_ApoLp
; 1; .
KO
K08757; -
; .
Pfam
PF01442; Apolipoprotein
; 1; .
World-2DPAGE Repository (search AC)
Database constructed and maintained by
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