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Searching in 'World-2DPAGE Repository [0022]' for entry matching: P04692 World-2DPAGE Repository (0022):  P04692 P04692 General information about the entry View entry in simple text format Entry name TPM1_RAT Primary accession number P04692 integrated into World-2DPAGE Repository (0022) on  May 7, 2010 (release 1) 2D Annotations were last modified on June 22, 2011 (version 2) General Annotations were last modified on  November 24, 2011 (version 2) Name and origin of the protein Description RecName: Full=Tropomyosin alpha-1 chain; AltName: Full=Alpha-tropomyosin; AltName: Full=Tropomyosin-1;. Gene name Name=Tpm1 Synonyms=Alpha-tm, Tpma Annotated species Rattus [TaxID: 10114] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000593; Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L. ''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity'' Proteomics 11(16):3369-3379 (2011) 2D PAGE maps for identified proteins How to interpret a protein HCR_LCR_HEART {HCR LCR Cardiac Map} Rattus Tissue: Heart   map experimental info   HCR_LCR_HEART MAP LOCATIONS: SPOT 530: pI=4.69; Mw=32718   [identification data] SPOT 546: pI=4.69; Mw=32718   [identification data] SPOT 631: pI=4.69; Mw=32718   [identification data] SPOT 876: pI=4.69; Mw=32718   [identification data] SPOT 899: pI=4.69; Mw=32718   [identification data] IDENTIFICATION: SPOT 530: SeqCov=37%. Peptides MS=16/20. Mascot PMF Score=160 [1] SPOT 546: SeqCov=35.9%. Peptides MS=16/20. Mascot PMF Score=161 [1]; SPOT 631: SeqCov=35.6%. Peptides MS=15/20. Mascot PMF Score=141 [1]; SPOT 876: SeqCov=37%. Peptides MS=16/20. Mascot PMF Score=161 [1]; SPOT 899: SeqCov=30.6%. Peptides MS=13/20. Mascot PMF Score=129 [1]. MAPPING (identification): SPOT 530: Peptide mass fingerprinting [1]; SPOT 546: Peptide mass fingerprinting [1]; SPOT 631: Peptide mass fingerprinting [1]; SPOT 876: Peptide mass fingerprinting [1]; SPOT 899: Peptide mass fingerprinting [1]. Copyright Data from Dr. Jatin Burniston, Liverpool John Moores University, UK Cross-references UniProtKB/Swiss-Prot P04692; TPM1_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name TPM1_RAT Primary accession number P04692 Secondary accession number(s) P06469 P18342 P18343 P18344 P19354 Q53X09 Q63582 Q63608 Q63609 Sequence was last modified on  April 4, 2006 (version 3) Annotations were last modified on  November 16, 2011 (version 108) Name and origin of the protein Description RecName: Full=Tropomyosin alpha-1 chain; AltName: Full=Alpha-tropomyosin; AltName: Full=Tropomyosin-1; Gene name Name=Tpm1 Synonyms=Alpha-tm, Tpma Encoded on Name=Tpm1; Synonyms=Alpha-tm, Tpma Keywords 3D-structure; Acetylation; Actin-binding; Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Isopeptide bond; Muscle protein; Phosphoprotein; Reference proteome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M15474; AAA21801.1; -; Genomic_DNA EMBL M15472; AAA21801.1; JOINED; Genomic_DNA EMBL M15473; AAA21801.1; JOINED; Genomic_DNA EMBL M16432; AAA21801.1; JOINED; Genomic_DNA EMBL M16433; AAA21801.1; JOINED; Genomic_DNA EMBL M18135; AAA21803.1; ALT_TERM; Genomic_DNA EMBL M16432; AAA21803.1; JOINED; Genomic_DNA EMBL M15472; AAA21803.1; JOINED; Genomic_DNA EMBL M16433; AAA21803.1; JOINED; Genomic_DNA EMBL M15473; AAA21803.1; JOINED; Genomic_DNA EMBL M18135; AAA21804.1; -; Genomic_DNA EMBL M16432; AAA21804.1; JOINED; Genomic_DNA EMBL M16433; AAA21804.1; JOINED; Genomic_DNA EMBL M18135; AAA21805.1; -; Genomic_DNA EMBL M16432; AAA21805.1; JOINED; Genomic_DNA EMBL M15472; AAA21805.1; JOINED; Genomic_DNA EMBL M16433; AAA21805.1; JOINED; Genomic_DNA EMBL X02411; CAA26258.1; ALT_SEQ; mRNA EMBL M34135; AAA42252.1; -; mRNA EMBL M34134; AAA42253.1; -; mRNA EMBL M34136; AAA42254.1; -; mRNA EMBL M34137; AAA40773.1; -; Genomic_DNA EMBL M34138; AAA40774.1; -; Genomic_DNA EMBL M60666; AAA42290.1; -; mRNA EMBL M60668; AAA18098.1; -; mRNA EMBL M60669; AAA18099.1; -; mRNA EMBL X02412; CAA26259.1; -; mRNA IPI IPI00197888; -; . IPI IPI00207964; -; . IPI IPI00231563; -; . IPI IPI00231566; -; . IPI IPI00231567; -; . IPI IPI00231568; -; . IPI IPI00391995; -; . IPI IPI00391997; -; . PIR A34787; A34787; . PIR A39816; A39816; . PIR B27407; B27407; . PIR B34787; B34787; . PIR C34787; C34787; . PIR C39816; C39816; . PIR D39816; D39816; . RefSeq NP_001029241.1; NM_001034069.1; . RefSeq NP_001029244.1; NM_001034072.1; . RefSeq NP_001029245.1; NM_001034073.1; . RefSeq NP_001029246.1; NM_001034074.1; . RefSeq NP_001029247.1; NM_001034075.1; . RefSeq NP_062004.1; NM_019131.2; . UniGene Rn.87540; -; . PDB 1IHQ; NMR; -; A/B=206-209 PDB 1MV4; NMR; -; A/B=251-284 PDB 1TMZ; NMR; -; A/B=1-14 PDB 2B9C; X-ray; 2.30 A; A/B=89-207 PDB 2G9J; NMR; -; A/B=1-14 C/D=251-284 PDBsum; 1IHQ; -; . PDBsum 1MV4; -; . PDBsum 1TMZ; -; . PDBsum 2B9C; -; . PDBsum 2G9J; -; . ProteinModelPortal P04692; -; . SMR P04692; 8-284; . DIP DIP-29020N; -; . IntAct P04692; 1; . STRING P04692; -; . PhosphoSite P04692; -; . Rat-heart-2DPAGE P04692; -; . PRIDE P04692; -; . Ensembl ENSRNOT00000024493; ENSRNOP00000024493; ENSRNOG00000018184; . Ensembl ENSRNOT00000024575; ENSRNOP00000024575; ENSRNOG00000018184; . Ensembl ENSRNOT00000024617; ENSRNOP00000024617; ENSRNOG00000018184; . Ensembl ENSRNOT00000024721; ENSRNOP00000024721; ENSRNOG00000018184; . GeneID 24851; -; . KEGG rno:24851; -; . UCSC NM_001034068; rat; . CTD 7168; -; . RGD 3898; Tpm1; . eggNOG maNOG09955; -; . HOVERGEN HBG107404; -; . NextBio 604620; -; . ArrayExpress P04692; -; . Genevestigator P04692; -; . GermOnline ENSRNOG00000018184; Rattus norvegicus; . GO GO:0005737; C:cytoplasm; IEA:UniProtKB-KW; . GO GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell; . GO GO:0003779; F:actin binding; IEA:UniProtKB-KW; . GO GO:0030049; P:muscle filament sliding; IDA:BHF-UCL; . GO GO:0030336; P:negative regulation of cell migration; IGI:BHF-UCL; . GO GO:0032781; P:positive regulation of ATPase activity; IDA:BHF-UCL; . GO GO:0045785; P:positive regulation of cell adhesion; IGI:BHF-UCL; . GO GO:0051496; P:positive regulation of stress fiber assembly; IGI:BHF-UCL; . GO GO:0031529; P:ruffle organization; IGI:BHF-UCL; . GO GO:0042060; P:wound healing; IGI:BHF-UCL; . InterPro IPR000533; Tropomyosin; . KO K10373; -; . Pfam PF00261; Tropomyosin; 1; . PRINTS PR00194; TROPOMYOSIN; . PROSITE PS00326; TROPOMYOSIN; 1; . World-2DPAGE Repository (search AC)