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Searching in 'World-2DPAGE Repository [0030]' for entry matching: P04961

World-2DPAGE Repository (0030):  P04961


General information about the entry
View entry in simple text format
Entry namePCNA_RAT
Primary accession numberP04961
integrated into World-2DPAGE Repository (0030) on November 9, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Proliferating cell nuclear antigen; Short=PCNA; AltName: Full=Cyclin;.
Gene nameName=Pcna
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C.
''Two-dimensional gel proteome reference map of INS-1E cells''
Proteomics 11(7):1365-1369 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7}
Rattus norvegicus (Rat)
  map experimental info

pI=4.48; Mw=38737  [identification data]
pI=4.41; Mw=39276  [identification data]

IDENTIFICATION: SPOT 1734: Mascot protein score=75. Number of peptides=2 [1]
SPOT 3021: Mascot protein score=260. Number of peptides=6 [1].
MAPPING (identification):
SPOT 1734: Tandem mass spectrometry [1];
SPOT 3021: Tandem mass spectrometry [1].

Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium
UniProtKB/Swiss-ProtP04961; PCNA_RAT.
World-2DPAGE RepositoryP04961; PCNA_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry namePCNA_RAT
Primary accession numberP04961
Sequence was last modified on August 13, 1987 (version 1)
Annotations were last modified on November 16, 2011 (version 98)
Name and origin of the protein
DescriptionRecName: Full=Proliferating cell nuclear antigen; Short=PCNA; AltName: Full=Cyclin;
Gene nameName=Pcna
Encoded onName=Pcna
KeywordsAcetylation; Complete proteome; DNA replication; DNA-binding; Isopeptide bond; Nucleus; Reference proteome; Ubl conjugation.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLY00047; CAA68261.1; -; mRNA
EMBLBC060570; AAH60570.1; -; mRNA
IPIIPI00200861; -; .
PIRA26631; WMRTET; .
RefSeqNP_071776.1; NM_022381.3; .
UniGeneRn.223; -; .
ProteinModelPortalP04961; -; .
SMRP04961; 1-260; .
STRINGP04961; -; .
EnsemblENSRNOT00000028887; ENSRNOP00000028887; ENSRNOG00000021264; .
GeneID25737; -; .
KEGGrno:25737; -; .
UCSCNM_022381; rat; .
CTD5111; -; .
RGD3269; Pcna; .
eggNOGroNOG14028; -; .
GeneTreeENSGT00390000004965; -; .
HOVERGENHBG000947; -; .
InParanoidP04961; -; .
OrthoDBEOG4933JJ; -; .
PhylomeDBP04961; -; .
NextBio607879; -; .
ArrayExpressP04961; -; .
GenevestigatorP04961; -; .
GermOnlineENSRNOG00000021264; Rattus norvegicus; .
GOGO:0043626; C:PCNA complex; IEA:InterPro; .
GOGO:0070557; C:PCNA-p21 complex; ISS:UniProtKB; .
GOGO:0030337; F:DNA polymerase processivity factor activity; IEA:InterPro; .
GOGO:0006260; P:DNA replication; IEA:UniProtKB-KW; .
GOGO:0007507; P:heart development; IEP:RGD; .
GOGO:0032077; P:positive regulation of deoxyribonuclease activity; ISS:UniProtKB; .
GOGO:0006275; P:regulation of DNA replication; IEA:InterPro; .
GOGO:0046686; P:response to cadmium ion; IEP:RGD; .
GOGO:0033993; P:response to lipid; IDA:RGD; .
GOGO:0019985; P:translesion synthesis; ISS:UniProtKB; .
InterProIPR000730; Pr_cel_nuc_antig; .
InterProIPR022649; Pr_cel_nuc_antig_C; .
InterProIPR022659; Pr_cel_nuc_antig_CS; .
InterProIPR022648; Pr_cel_nuc_antig_N; .
KOK04802; -; .
PANTHERPTHR11352; Pr_cel_nuc_antig; 1; .
PfamPF02747; PCNA_C; 1; .
PfamPF00705; PCNA_N; 1; .
TIGRFAMsTIGR00590; Pcna; 1; .
PROSITEPS01251; PCNA_1; 1; .
PROSITEPS00293; PCNA_2; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server