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Searching in 'World-2DPAGE Repository [0030]' for entry matching: P05370




World-2DPAGE Repository (0030):  P05370


P05370


General information about the entry
View entry in simple text format
Entry nameG6PD_RAT
Primary accession numberP05370
integrated into World-2DPAGE Repository (0030) on November 9, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Glucose-6-phosphate 1-dehydrogenase; Short=G6PD; EC=1.1.1.49;.
Gene nameName=G6pdx
Synonyms=G6pd
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/pmic.201000006;
D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C.
''Two-dimensional gel proteome reference map of INS-1E cells''
Proteomics 11(7):1365-1369 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7}
Rattus norvegicus (Rat)
RAT_INS1E_4-7
  map experimental info
 
RAT_INS1E_4-7

MAP LOCATIONS:
pI=6.28; Mw=71100  [identification data]
pI=6.23; Mw=68304  [identification data]

IDENTIFICATION: SPOT 763: Mascot protein score=417. Number of peptides=13 [1]
SPOT 835: Mascot protein score=181. Number of peptides=8 [1].
MAPPING (identification):
SPOT 763: Tandem mass spectrometry [1];
SPOT 835: Tandem mass spectrometry [1].

Copyright
Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium
Cross-references
UniProtKB/Swiss-ProtP05370; G6PD_RAT.
World-2DPAGE RepositoryP05370; G6PD_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameG6PD_RAT
Primary accession numberP05370
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on November 16, 2011 (version 113)
Name and origin of the protein
DescriptionRecName: Full=Glucose-6-phosphate 1-dehydrogenase; Short=G6PD; EC=1.1.1.49;
Gene nameName=G6pdx
Synonyms=G6pd
Encoded onName=G6pdx; Synonyms=G6pd
KeywordsAcetylation; Carbohydrate metabolism; Complete proteome; Direct protein sequencing; Glucose metabolism; NADP; Oxidoreductase; Phosphoprotein; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX07467; CAA30355.1; -; mRNA
EMBLBC081820; AAH81820.1; -; mRNA
EMBLM26655; AAA41179.1; -; Genomic_DNA
EMBLM26653; AAA41179.1; JOINED; Genomic_DNA
EMBLM26654; AAA41179.1; JOINED; Genomic_DNA
IPIIPI00231637; -; .
PIRS01233; S01233; .
RefSeqNP_058702.1; NM_017006.2; .
UniGeneRn.11040; -; .
ProteinModelPortalP05370; -; .
SMRP05370; 28-515; .
STRINGP05370; -; .
PhosphoSiteP05370; -; .
World-2DPAGE0004:P05370; -; .
PRIDEP05370; -; .
EnsemblENSRNOT00000056317; ENSRNOP00000053157; ENSRNOG00000037254; .
GeneID24377; -; .
KEGGrno:24377; -; .
CTD2539; -; .
RGD2645; G6pdx; .
eggNOGmaNOG04087; -; .
GeneTreeENSGT00530000063435; -; .
HOVERGENHBG000856; -; .
InParanoidP05370; -; .
OrthoDBEOG4VHK69; -; .
PhylomeDBP05370; -; .
NextBio603131; -; .
ArrayExpressP05370; -; .
GenevestigatorP05370; -; .
GermOnlineENSRNOG00000037254; Rattus norvegicus; .
GOGO:0005829; C:cytosol; IDA:RGD; .
GOGO:0005792; C:microsome; IDA:RGD; .
GOGO:0005634; C:nucleus; IDA:RGD; .
GOGO:0005625; C:soluble fraction; IDA:RGD; .
GOGO:0005536; F:glucose binding; IDA:RGD; .
GOGO:0004345; F:glucose-6-phosphate dehydrogenase activity; IDA:RGD; .
GOGO:0050661; F:NADP binding; IDA:RGD; .
GOGO:0051156; P:glucose 6-phosphate metabolic process; IDA:RGD; .
GOGO:0009051; P:pentose-phosphate shunt; oxidative branch; IMP:RGD
GOGO:0045767; P:regulation of anti-apoptosis; IDA:RGD; .
GOGO:0045471; P:response to ethanol; IDA:RGD; .
GOGO:0032094; P:response to food; IEP:RGD; .
GOGO:0014070; P:response to organic cyclic compound; IEP:RGD; .
InterProIPR001282; G6P_DH; .
InterProIPR019796; G6P_DH_AS; .
InterProIPR022675; G6P_DH_C; .
InterProIPR022674; G6P_DH_NAD-bd; .
InterProIPR016040; NAD(P)-bd_dom; .
Gene3DG3DSA:3.40.50.720; NAD(P)-bd; 1; .
KOK00036; -; .
PANTHERPTHR23429; G6PDH; 1; .
PfamPF02781; G6PD_C; 1; .
PfamPF00479; G6PD_N; 1; .
PIRSFPIRSF000110; G6PD; 1; .
PRINTSPR00079; G6PDHDRGNASE; .
TIGRFAMsTIGR00871; Zwf; 1; .
PROSITEPS00069; G6P_DEHYDROGENASE; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server