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Searching in 'World-2DPAGE Repository [0019]' for entry matching: P05432




World-2DPAGE Repository (0019):  P05432

P05432


General information about the entry
View entry in simple text format
Entry nameERRFI_RAT
Primary accession numberP05432
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=ERBB receptor feedback inhibitor 1; AltName: Full=Gene 33 polypeptide; AltName: Full=Mitogen-inducible gene 6 protein homolog; Short=MIG-6; AltName: Full=Receptor-associated late transducer; Short=RALT;.
Gene nameName=Errfi1
Synonyms=33, Mig6
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1111/j.1471-4159.2010.06719.x;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
HIPP_SYNAP
  map experimental info 		 
HIPP_SYNAP

MAP LOCATIONS:
pI=8.12; Mw=50707  [identification data]

IDENTIFICATION: SPOT 1037: Peptides number=5. SeqCov=17.2%. MOWSE score=2.04E+2 [1].
MAPPING (identification):
SPOT 1037: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-ProtP05432; ERRFI_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameERRFI_RAT
Primary accession numberP05432
Sequence was last modified on November 1, 1988 (version 1)
Annotations were last modified on October 19, 2011 (version 86)
Name and origin of the protein
DescriptionRecName: Full=ERBB receptor feedback inhibitor 1; AltName: Full=Gene 33 polypeptide; AltName: Full=Mitogen-inducible gene 6 protein homolog; Short=MIG-6; AltName: Full=Receptor-associated late transducer; Short=RALT;
Gene nameName=Errfi1
Synonyms=33, Mig6
Encoded onName=Errfi1; Synonyms=33, Mig6
KeywordsAlternative splicing; Cell membrane; Complete proteome; Cytoplasm; Membrane; Nucleus; Phosphoprotein; Reference proteome; Tumor suppressor.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM23572; AAB08828.1; -; Genomic_DNA
EMBLM23570; AAB08828.1; JOINED; Genomic_DNA
EMBLM23571; AAB08828.1; JOINED; Genomic_DNA
EMBLX07266; CAA30252.1; -; mRNA
EMBLBC083845; AAH83845.1; -; mRNA
IPIIPI00199550; -; .
IPIIPI00480778; -; .
PIRS03116; S03116; .
RefSeqNP_001014093.1; NM_001014071.1; .
UniGeneRn.100336; -; .
ProteinModelPortalP05432; -; .
SMRP05432; 334-360; .
STRINGP05432; -; .
PhosphoSiteP05432; -; .
PRIDEP05432; -; .
EnsemblENSRNOT00000024606; ENSRNOP00000024606; ENSRNOG00000018275; .
GeneID313729; -; .
KEGGrno:313729; -; .
NMPDRfig|10116.3.peg.24471; -; .
UCSCNM_001014071; rat; .
CTD54206; -; .
RGD1307599; Errfi1; .
eggNOGroNOG13289; -; .
GeneTreeENSGT00440000033870; -; .
HOVERGENHBG031710; -; .
InParanoidP05432; -; .
OMADPITMAY; -; .
OrthoDBEOG4CVG6X; -; .
PhylomeDBP05432; -; .
NextBio666720; -; .
ArrayExpressP05432; -; .
GenevestigatorP05432; -; .
GermOnlineENSRNOG00000018275; Rattus norvegicus; .
GOGO:0005737; C:cytoplasm; ISS:UniProtKB; .
GOGO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB; .
GOGO:0005634; C:nucleus; IEA:UniProtKB-SubCell; .
GOGO:0048286; P:lung alveolus development; ISS:UniProtKB; .
GOGO:0060428; P:lung epithelium development; ISS:UniProtKB; .
GOGO:0060426; P:lung vasculature development; ISS:UniProtKB; .
GOGO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IDA:UniProtKB; .
GOGO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB; .
GOGO:0031953; P:negative regulation of protein autophosphorylation; ISS:UniProtKB; .
GOGO:0045616; P:regulation of keratinocyte differentiation; ISS:UniProtKB; .
GOGO:0043589; P:skin morphogenesis; ISS:UniProtKB; .
InterProIPR015116; GTPase_binding; .
InterProIPR021619; Inhibitor_Mig-6; .
PfamPF09027; GTPase_binding; 1; .
PfamPF11555; Inhibitor_Mig-6; 1; .


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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server