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World-2DPAGE Repository

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Searching in 'World-2DPAGE Repository [0004]' for entry matching: P05708

World-2DPAGE Repository (0004):  P05708


General information about the entry
View entry in simple text format
Entry nameHXK1_RAT
Primary accession numberP05708
integrated into World-2DPAGE Repository (0004) on October 13, 2008 (release 1)
2D Annotations were last modified onMay 18, 2011 (version 2)
General Annotations were last modified on December 22, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Hexokinase-1; EC=; AltName: Full=Brain form hexokinase; AltName: Full=Hexokinase type I; Short=HK I;.
Gene nameName=Hk1
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
PubMed=19343716; DOI=10.1002/pmic.200800664; [NCBI, EBI, Israel, Japan]
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of the mature rat olfactory bulb''
Proteomics 9(1):2593-2599 (2009)
2D PAGE maps for identified proteins
How to interpret a protein

OB21DSUB {2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb
  map experimental info

pI=6.35; Mw=95000  [identification data]

MAPPING (identification):
SPOT 94: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
UniProtKB/Swiss-ProtP05708; HXK1_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameHXK1_RAT
Primary accession numberP05708
Sequence was last modified on May 30, 2000 (version 4)
Annotations were last modified on November 16, 2011 (version 113)
Name and origin of the protein
DescriptionRecName: Full=Hexokinase-1; EC=; AltName: Full=Brain form hexokinase; AltName: Full=Hexokinase type I; Short=HK I;
Gene nameName=Hk1
Encoded onName=Hk1
Keywords3D-structure; Acetylation; Allosteric enzyme; ATP-binding; Complete proteome; Direct protein sequencing; Glycolysis; Kinase; Membrane; Mitochondrion; Mitochondrion outer membrane; Nucleotide-binding; Phosphoprotein; Reference proteome; Repeat; Transferase.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLJ04526; AAC20075.1; -; mRNA
EMBLU27319; AAC52945.1; -; Genomic_DNA
EMBLU89160; AAB71376.1; -; Genomic_DNA
EMBLU89158; AAB71374.1; -; Genomic_DNA
IPIIPI00202543; -; .
PIRA32521; A32521; .
PIRB32521; B32521; .
PIRC32521; C32521; .
PIRC59226; C59226; .
RefSeqNP_036866.1; NM_012734.1; .
UniGeneRn.11017; -; .
PDB1BG3; X-ray; 2.80 A; A/B=1-918
PDBsum1BG3; -; .
ProteinModelPortalP05708; -; .
SMRP05708; 1-911; .
PhosphoSiteP05708; -; .
World-2DPAGE0004:P05708; -; .
PRIDEP05708; -; .
GeneID25058; -; .
KEGGrno:25058; -; .
CTD3098; -; .
RGD2796; Hk1; .
HOVERGENHBG005020; -; .
PhylomeDBP05708; -; .
BRENDA2.7.1.1; 5301; .
NextBio605272; -; .
GenevestigatorP05708; -; .
GOGO:0005901; C:caveola; IDA:RGD; .
GOGO:0005829; C:cytosol; IDA:RGD; .
GOGO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell; .
GOGO:0043234; C:protein complex; IDA:RGD; .
GOGO:0005524; F:ATP binding; IDA:RGD; .
GOGO:0016887; F:ATPase activity; IC:RGD; .
GOGO:0004340; F:glucokinase activity; IDA:RGD; .
GOGO:0005536; F:glucose binding; IDA:RGD; .
GOGO:0032403; F:protein complex binding; IDA:RGD; .
GOGO:0042803; F:protein homodimerization activity; IDA:RGD; .
GOGO:0004672; F:protein kinase activity; IDA:RGD; .
GOGO:0006096; P:glycolysis; IDA:RGD; .
GOGO:0043066; P:negative regulation of apoptotic process; IMP:RGD; .
GOGO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD; .
GOGO:0018107; P:peptidyl-threonine phosphorylation; IDA:RGD; .
GOGO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:RGD; .
GOGO:0046777; P:protein autophosphorylation; IDA:RGD; .
GOGO:0010359; P:regulation of anion channel activity; IDA:RGD; .
InterProIPR001312; Hexokinase; .
InterProIPR022673; Hexokinase_C; .
InterProIPR019807; Hexokinase_CS; .
InterProIPR022672; Hexokinase_N; .
KOK00844; -; .
PANTHERPTHR19443; Hexokinase; 1; .
PfamPF00349; Hexokinase_1; 2; .
PfamPF03727; Hexokinase_2; 2; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server