World-2DPAGE Repository

RecName: Full=NAD(P)H dehydrogenase [quinone] 1; EC=1.6.5.2; AltName: Full=Azoreductase; AltName: Full=DT-diaphorase; Short=DTD; AltName: Full=Menadione reductase; AltName: Full=NAD(P)H:quinone oxidoreductase 1; AltName: Full=Phylloquinone reductase; AltName: Full=Quinone reductase 1; Short=QR1;.

Gene name

Name=Nqo1
Synonyms=Nmor1

Annotated species

Rattus norvegicus (Rat) [TaxID: 10116]

Taxonomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.

References

[1]	MAPPING ON GEL PubMed=19343716; DOI=10.1002/pmic.200800664; [NCBI, EBI, Israel, Japan] Maurya D.K., Sundaram C.S., Bhargava P. ''Proteome profile of the mature rat olfactory bulb'' Proteomics 9(1):2593-2599 (2009)

2D PAGE maps for identified proteins

How to interpret a protein

OB21DSUB {2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb

map experimental info

OB21DSUB

MAP LOCATIONS:

SPOT 567:

pI=8.31; Mw=34000

[identification data]

MAPPING (identification):

SPOT 567: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India

Cross-references

UniProtKB/Swiss-Prot

P05982; NQO1_RAT.

2D PAGE maps for identified proteins
How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry name	NQO1_RAT
Primary accession number	P05982
Secondary accession number(s)	Q63478
Sequence was last modified on	January 23, 2007 (version 4)
Annotations were last modified on	November 16, 2011 (version 114)
Name and origin of the protein
Description	RecName: Full=NAD(P)H dehydrogenase [quinone] 1; EC=1.6.5.2; AltName: Full=Azoreductase; AltName: Full=DT-diaphorase; Short=DTD; AltName: Full=Menadione reductase; AltName: Full=NAD(P)H:quinone oxidoreductase 1; AltName: Full=Phylloquinone reductase; AltName: Full=Quinone reductase 1; Short=QR1;
Gene name	Name=Nqo1 Synonyms=Nmor1
Encoded on	Name=Nqo1; Synonyms=Nmor1
Keywords	3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; FAD; Flavoprotein; NAD; NADP; Oxidoreductase; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL	J02608; AAA41716.1; -; mRNA
EMBL	J02679; AAA41715.1; -; mRNA
EMBL	M36660; AAA39829.1; -; mRNA
EMBL	J02640; AAA41988.1; ALT_INIT; mRNA
EMBL	M31805; AAA41989.1; -; Genomic_DNA
EMBL	M31801; AAA41989.1; JOINED; Genomic_DNA
EMBL	M31802; AAA41989.1; JOINED; Genomic_DNA
EMBL	M31804; AAA41989.1; JOINED; Genomic_DNA
EMBL	M33039; AAA41990.1; -; Genomic_DNA
EMBL	M33038; AAA41990.1; JOINED; Genomic_DNA
EMBL	BC083542; AAH83542.1; -; mRNA
EMBL	X17464; -; NOT_ANNOTATED_CDS; mRNA
IPI	IPI00231595; -; .
PIR	A34162; A34162; .
RefSeq	NP_058696.2; NM_017000.3; .
UniGene	Rn.11234; -; .
PDB	1QRD; X-ray; 2.40 A; A/B=2-274
PDBsum	1QRD; -; .
ProteinModelPortal	P05982; -; .
SMR	P05982; 2-274; .
IntAct	P05982; 1; .
STRING	P05982; -; .
World-2DPAGE	0004:P05982; -; .
PRIDE	P05982; -; .
Ensembl	ENSRNOT00000017174; ENSRNOP00000017175; ENSRNOG00000012772; .
GeneID	24314; -; .
KEGG	rno:24314; -; .
NMPDR	fig\|10116.3.peg.14965; -; .
UCSC	NM_017000; rat; .
CTD	1728; -; .
RGD	2503; Nqo1; .
eggNOG	roNOG08878; -; .
GeneTree	ENSGT00440000033410; -; .
HOVERGEN	HBG029104; -; .
InParanoid	P05982; -; .
OrthoDB	EOG44BB36; -; .
PhylomeDB	P05982; -; .
NextBio	602959; -; .
ArrayExpress	P05982; -; .
Genevestigator	P05982; -; .
GermOnline	ENSRNOG00000012772; Rattus norvegicus; .
GO	GO:0005829; C:cytosol; IDA:RGD; .
GO	GO:0043025; C:neuronal cell body; IDA:RGD; .
GO	GO:0050662; F:coenzyme binding; IEA:InterPro; .
GO	GO:0009055; F:electron carrier activity; IEA:InterPro; .
GO	GO:0003955; F:NAD(P)H dehydrogenase (quinone) activity; IDA:RGD; .
GO	GO:0004784; F:superoxide dismutase activity; IMP:RGD; .
GO	GO:0007568; P:aging; IEP:RGD; .
GO	GO:0043525; P:positive regulation of neuron apoptosis; IMP:RGD; .
GO	GO:0032355; P:response to estradiol stimulus; IEP:RGD; .
GO	GO:0045471; P:response to ethanol; IEP:RGD; .
GO	GO:0007584; P:response to nutrient; IEP:RGD; .
GO	GO:0014070; P:response to organic cyclic compound; IEP:RGD; .
GO	GO:0006979; P:response to oxidative stress; IEP:RGD; .
GO	GO:0006801; P:superoxide metabolic process; IMP:RGD; .
InterPro	IPR003680; Flavodoxin_fold; .
KO	K00355; -; .
Pfam	PF02525; Flavodoxin_2; 1; .

World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server

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