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World-2DPAGE Repository

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Searching in 'World-2DPAGE Repository [0022]' for entry matching: P08461

World-2DPAGE Repository (0022): P08461


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AC   P08461;
DT   07-May-2010, integrated into [0022] - HCR LCR Cardiac Mapy (release 1).
DT   22-Jun-2011, 2D annotation version 2.
DT   24-Nov-2011, general annotation version 2.
DE   RecName: Full=Dihydrolipoyllysine-residue acetyltransferase component of
DE   pyruvate dehydrogenase complex, mitochondrial; EC=; AltName:
DE   Full=70 kDa mitochondrial autoantigen of primary biliary cirrhosis;
DE   Short=PBC; AltName: Full=Dihydrolipoamide acetyltransferase component of
DE   pyruvate dehydrogenase complex; AltName: Full=Pyruvate dehydrogenase
DE   complex component E2; Short=PDC-E2; Short=PDCE2; Flags: Precursor;.
GN   Name=Dlat;
OS   Rattus.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae.
OX   NCBI_TaxID=10114;
RN   [1]
RX   DOI=10.1002/pmic.201000593;
RA   Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch
RA   L.G., Britton S.L.;
RT   ''Proteomic analysis reveals perturbed energy metabolism and elevated
RT   oxidative stress in hearts of rats with inborn low aerobic capacity'';
RL   Proteomics 11(16):3369-3379 (2011).
2D   -!-   PI/MW: SPOT 147=8.76/67637;
2D   -!-   PI/MW: SPOT 172=8.76/67637;
2D   -!-   PI/MW: SPOT 618=8.76/67637;
2D   -!-   PI/MW: SPOT 781=8.76/67637;
2D   -!-   IDENTIFICATION: SPOT 147: SeqCov=20.4%. Peptides MS=10/20. Mascot
2D         PMF Score=62 [1]; SPOT 172: SeqCov=21.7%. Peptides MS=11/20. Mascot PMF
2D         Score=73 [1]; SPOT 618: SeqCov=22.6%. Peptides MS=10/20. Mascot PMF
2D         Score=79 [1]; SPOT 781: SeqCov=19.1%. Peptides MS=7/20. Mascot PMF
2D         Score=48 [1].
2D   -!-   PEPTIDE EVIDENCE: SPOT 147: 139-ILVPEGTR-146 (21) /
2D         397-VAPTPAGVFIDIPISNIR-414 (101) / 426-QTIPHYYLSVDVNMGEVLLVR-446 (21)
2D         [1]; SPOT 172: 139-ILVPEGTR-146 (34) / 383-AAPAAAAAAPPGPR-396 (43) /
2D         397-VAPTPAGVFIDIPISNIR-414 (78) [1]; SPOT 618: 139-ILVPEGTR-146 (31) /
2D         383-AAPAAAAAAPPGPR-396 (40) / 397-VAPTPAGVFIDIPISNIR-414 (119) [1]; SPOT
2D         781: 397-VAPTPAGVFIDIPISNIR-414 (48) [1].
2D   -!-   MAPPING: SPOT 147: Peptide mass fingerprinting [1]; SPOT 147:
2D         Tandem mass spectrometry [1]; SPOT 172: Peptide mass fingerprinting [1];
2D         SPOT 172: Tandem mass spectrometry [1]; SPOT 618: Peptide mass
2D         fingerprinting [1]; SPOT 618: Tandem mass spectrometry [1]; SPOT 781:
2D         Peptide mass fingerprinting [1]; SPOT 781: Tandem mass spectrometry [1].
CC   ---------------------------------------------------------------------------
CC   Data from Dr. Jatin Burniston, Liverpool John Moores University, UK
CC   ---------------------------------------------------------------------------
DR   UniProtKB/Swiss-Prot; P08461; ODP2_RAT.

The following 2-D map is available for this protein:
HCR LCR Cardiac Map

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World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server