resource logo

World-2DPAGE Repository

Attention: World-2DPAGE is no longer maintained. Previously submitted data can still be queried at World-2DPAGE Repository.

World-2DPAGE Repository 
Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]


use 'Ctrl' to select several

Select Remote Interfaces
[All Interfaces]
World-2DPAGE Portal

Exclude local DBs
has only effect if a remote
interface is selected
Searching in 'World-2DPAGE Repository [0019]' for entry matching: P09606

World-2DPAGE Repository (0019):  P09606


General information about the entry
View entry in simple text format
Entry nameGLNA_RAT
Primary accession numberP09606
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Glutamine synthetase; Short=GS; EC=; AltName: Full=Glutamate decarboxylase; EC=; AltName: Full=Glutamate--ammonia ligase;.
Gene nameName=Glul
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
  map experimental info

pI=6.47; Mw=42982  [identification data]
pI=6.64; Mw=42981  [identification data]

IDENTIFICATION: SPOT 524: Peptides number=4. SeqCov=9.7%. MOWSE score=1.91E+3 [1]
SPOT 536: Peptides number=6. SeqCov=17.7%. MOWSE score=4.01E+7 [1].
MAPPING (identification):
SPOT 524: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 536: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Data from Dr. Willard Freeman, Penn State College of Medicine, USA
UniProtKB/Swiss-ProtP09606; GLNA_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameGLNA_RAT
Primary accession numberP09606
Secondary accession number(s) Q6P7Q9
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on November 16, 2011 (version 105)
Name and origin of the protein
DescriptionRecName: Full=Glutamine synthetase; Short=GS; EC=; AltName: Full=Glutamate decarboxylase; EC=; AltName: Full=Glutamate--ammonia ligase;
Gene nameName=Glul
Encoded onName=Glul; Synonyms=Glns
KeywordsAcetylation; ATP-binding; Complete proteome; Cytoplasm; Direct protein sequencing; Ligase; Lyase; Mitochondrion; Nucleotide-binding; Phosphoprotein; Reference proteome.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLX07921; CAA30754.1; -; mRNA
EMBLM29599; AAA65096.1; -; Genomic_DNA
EMBLM29595; AAA65096.1; JOINED; Genomic_DNA
EMBLM29596; AAA65096.1; JOINED; Genomic_DNA
EMBLM29597; AAA65096.1; JOINED; Genomic_DNA
EMBLM29598; AAA65096.1; JOINED; Genomic_DNA
EMBLM29579; AAA65095.1; -; mRNA
EMBLM91652; AAC42038.1; -; mRNA
EMBLBC061559; AAH61559.1; -; mRNA
EMBLBC072694; AAH72694.1; -; mRNA
IPIIPI00324020; -; .
PIRS01242; AJRTQ; .
RefSeqNP_058769.4; NM_017073.3; .
UniGeneRn.2204; -; .
ProteinModelPortalP09606; -; .
SMRP09606; 3-372; .
IntActP09606; 1; .
PhosphoSiteP09606; -; .
World-2DPAGE0004:P09606; -; .
PRIDEP09606; -; .
GeneID24957; -; .
KEGGrno:24957; -; .
CTD2752; -; .
RGD2710; Glul; .
eggNOGmaNOG04435; -; .
HOVERGENHBG005847; -; .
PhylomeDBP09606; -; .
NextBio604985; -; .
GenevestigatorP09606; -; .
GOGO:0043679; C:axon terminus; IDA:RGD; .
GOGO:0005792; C:microsome; IDA:RGD; .
GOGO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell; .
GOGO:0043204; C:perikaryon; IDA:RGD; .
GOGO:0043234; C:protein complex; IDA:RGD; .
GOGO:0005791; C:rough endoplasmic reticulum; IDA:RGD; .
GOGO:0005625; C:soluble fraction; IDA:RGD; .
GOGO:0019717; C:synaptosome; IDA:RGD; .
GOGO:0005524; F:ATP binding; IDA:RGD; .
GOGO:0045503; F:dynein light chain binding; IPI:RGD; .
GOGO:0016595; F:glutamate binding; IDA:RGD; .
GOGO:0004351; F:glutamate decarboxylase activity; IEA:EC; .
GOGO:0004356; F:glutamate-ammonia ligase activity; IDA:RGD; .
GOGO:0000287; F:magnesium ion binding; IDA:RGD; .
GOGO:0030145; F:manganese ion binding; IDA:RGD; .
GOGO:0019676; P:ammonia assimilation cycle; IDA:RGD; .
GOGO:0006542; P:glutamine biosynthetic process; IDA:RGD; .
GOGO:0042133; P:neurotransmitter metabolic process; TAS:RGD; .
GOGO:0050679; P:positive regulation of epithelial cell proliferation; IMP:RGD; .
GOGO:0032024; P:positive regulation of insulin secretion; IMP:RGD; .
GOGO:0051968; P:positive regulation of synaptic transmission; glutamatergic; IMP:RGD
GOGO:0051260; P:protein homooligomerization; IDA:RGD; .
InterProIPR008147; Gln_synt_beta; .
InterProIPR014746; Gln_synth/guanido_kin_cat_dom; .
InterProIPR008146; Gln_synth_cat_dom; .
Gene3DG3DSA:3.30.590.10; ATP-gua_Ptrans; 1; .
Gene3DG3DSA:; G3DSA:; 1; .
KOK01915; -; .
PfamPF00120; Gln-synt_C; 1; .
PfamPF03951; Gln-synt_N; 1; .
SUPFAMSSF54368; Gln_synt_beta; 1; .
PROSITEPS00180; GLNA_1; 1; .

World-2DPAGE Repository image

World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server