World-2DPAGE Repository

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.

References

[1]	MAPPING ON GEL PubMed=19343716; DOI=10.1002/pmic.200800664; [NCBI, EBI, Israel, Japan] Maurya D.K., Sundaram C.S., Bhargava P. ''Proteome profile of the mature rat olfactory bulb'' Proteomics 9(1):2593-2599 (2009)

2D PAGE maps for identified proteins

How to interpret a protein

OB21DSUB {2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb

map experimental info

OB21DSUB

MAP LOCATIONS:

SPOT 43:

pI=5.50; Mw=191000

[identification data]

MAPPING (identification):

SPOT 43: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India

Cross-references

UniProtKB/Swiss-Prot

P11442; CLH_RAT.

2D PAGE maps for identified proteins
How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry name	CLH_RAT
Primary accession number	P11442
Sequence was last modified on	January 23, 2007 (version 3)
Annotations were last modified on	November 16, 2011 (version 101)
Name and origin of the protein
Description	RecName: Full=Clathrin heavy chain 1;
Gene name	Name=Cltc
Encoded on	Name=Cltc
Keywords	3D-structure; Acetylation; Coated pit; Complete proteome; Cytoplasmic vesicle; Direct protein sequencing; Membrane; Phosphoprotein; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL	J03583; AAA40874.1; -; mRNA
IPI	IPI00193983; -; .
PIR	A39941; LRRTH; .
RefSeq	NP_062172.1; NM_019299.1; .
UniGene	Rn.3589; -; .
PDB	1BPO; X-ray; 2.60 A; A/B/C=1-494
PDB	1C9I; X-ray; 2.90 A; A/B=1-359
PDB	1C9L; X-ray; 2.90 A; A/B=3-359
PDBsum	1BPO; -; .
PDBsum	1C9I; -; .
PDBsum	1C9L; -; .
ProteinModelPortal	P11442; -; .
SMR	P11442; 1-493; 1182-1516; .
IntAct	P11442; 1; .
MINT	MINT-93121; -; .
STRING	P11442; -; .
PhosphoSite	P11442; -; .
World-2DPAGE	0004:P11442; -; .
PRIDE	P11442; -; .
GeneID	54241; -; .
KEGG	rno:54241; -; .
UCSC	NM_019299; rat; .
CTD	1213; -; .
RGD	2364; Cltc; .
eggNOG	roNOG05981; -; .
GeneTree	ENSGT00400000022107; -; .
HOVERGEN	HBG005344; -; .
PhylomeDB	P11442; -; .
Reactome	REACT_111984; Signal Transduction; .
NextBio	610700; -; .
ArrayExpress	P11442; -; .
Genevestigator	P11442; -; .
GermOnline	ENSRNOG00000004291; Rattus norvegicus; .
GO	GO:0030132; C:clathrin coat of coated pit; IEA:InterPro; .
GO	GO:0030130; C:clathrin coat of trans-Golgi network vesicle; IEA:InterPro; .
GO	GO:0030669; C:clathrin-coated endocytic vesicle membrane; TAS:Reactome; .
GO	GO:0042470; C:melanosome; IEA:UniProtKB-SubCell; .
GO	GO:0005624; C:membrane fraction; IDA:RGD; .
GO	GO:0005819; C:spindle; IDA:UniProtKB; .
GO	GO:0030315; C:T-tubule; IDA:RGD; .
GO	GO:0030506; F:ankyrin binding; IDA:RGD; .
GO	GO:0031072; F:heat shock protein binding; IDA:RGD; .
GO	GO:0042277; F:peptide binding; IDA:RGD; .
GO	GO:0008022; F:protein C-terminus binding; IPI:RGD; .
GO	GO:0005198; F:structural molecule activity; IEA:InterPro; .
GO	GO:0007030; P:Golgi organization; IMP:RGD; .
GO	GO:0006886; P:intracellular protein transport; IEA:InterPro; .
GO	GO:0007067; P:mitosis; IMP:UniProtKB; .
GO	GO:0006898; P:receptor-mediated endocytosis; IMP:UniProtKB; .
InterPro	IPR016024; ARM-type_fold; .
InterPro	IPR000547; Clathrin_H-chain/VPS_repeat; .
InterPro	IPR016025; Clathrin_H-chain_link/propller; .
InterPro	IPR015348; Clathrin_H-chain_linker_core; .
InterPro	IPR001473; Clathrin_H-chain_propeller_N; .
InterPro	IPR022365; Clathrin_H-chain_propeller_rpt; .
InterPro	IPR016341; Clathrin_heavy_chain; .
InterPro	IPR011990; TPR-like_helical; .
Gene3D	G3DSA:2.130.10.110; Clathrin_H-chain_link/propller; 1; .
Gene3D	G3DSA:1.25.40.10; TPR-like_helical; 3; .
KO	K04646; -; .
Pfam	PF00637; Clathrin; 7; .
Pfam	PF09268; Clathrin-link; 1; .
Pfam	PF01394; Clathrin_propel; 3; .
PIRSF	PIRSF002290; Clathrin_H_chain; 1; .
SMART	SM00299; CLH; 7; .
SUPFAM	SSF48371; ARM-type_fold; 5; .
SUPFAM	SSF50989; Clathrin_H-chain_propeller_N; 1; .

World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server

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