World-2DPAGE Repository
Home
|
Contact
!!This displayer contains script commands. You should enable JavaScripting within your browser preferences, or use another browser!
World-2DPAGE Repository
Search by
[accession number]
[description, ID or gene]
[author names]
[spot ID / serial number]
[identification methods]
[pI / Mw range]
[combined fields]
Maps
[experimental info]
[protein list]
[graphical interface]
Databases
0001
0002
0003
0004
0005
0006
0007
0008
0009
0010
0011
0012
0014
0017
0018
0019
0020
0021
0022
0023
0024
0026
0027
0029
0030
0031
0032
0034
0035
0036
0037
0038
0039
0040
0042
0043
0044
0046
0047
0050
0051
0053
0054
0056
0059
0061
0062
0063
0066
0068
0069
0076
0077
0080
0084
0085
0088
use 'Ctrl' to select several
databases
Select Remote Interfaces
[All Interfaces]
SWISS-2DPAGE
World-2DPAGE Portal
Exclude local DBs
has only effect if a remote
interface is selected
Searching in 'World-2DPAGE Repository [0014]' for entry
matching:
P11884
World-2DPAGE Repository
(0014):
P11884
P11884
General information about the entry
View entry in simple text format
Entry name
ALDH2_RAT
Primary accession number
P11884
integrated into World-2DPAGE Repository (0014) on
October 13, 2008 (release 1)
2D Annotations were last modified on
June 1, 2011 (version 3)
General Annotations were last modified on
November 25, 2011 (version 2)
Name and origin of the protein
Description
RecName: Full=Aldehyde dehydrogenase, mitochondrial; EC=1.2.1.3; AltName: Full=ALDH class 2; AltName: Full=ALDH-E2; AltName: Full=ALDH1; Flags: Precursor;.
Gene name
Name=Aldh2
Annotated species
Rattus norvegicus (Rat) [TaxID:
10116
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]
2D-PAGE GEL CHARACTERIZATION
DOI=
10.1002/pmic.200900680
;
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of whole cerebellum of the mature rat''
Proteomics 10(23):4311-4319 (2010)
2D PAGE maps for identified proteins
How to interpret a protein
RAT_CEREBELLUM_21D
{Proteome of 21 days old rat cerebellum}
Rattus norvegicus (Rat)
Tissue: Cerebellum
map experimental info
RAT_CEREBELLUM_21D
MAP LOCATIONS:
SPOT 3365
:
pI=6.74; Mw=58000
[identification data]
IDENTIFICATION:
SPOT 3365: SeqCov=23%. MascotPMF=70 [
1
].
MAPPING (identification):
SPOT
3365
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
].
Copyright
Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
Cross-references
PRIDE
10017.
UniProtKB/Swiss-Prot
P11884; ALDH2_RAT.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
2011_11
Entry name
ALDH2_RAT
Primary accession number
P11884
Secondary accession number(s)
Q6Q288 Q6Q289 Q6Q290 Q8K3V8 Q91ZD7
Sequence was last modified on
October 1, 1989 (version 1)
Annotations were last modified on
November 16, 2011 (version 115)
Name and origin of the protein
Description
RecName: Full=Aldehyde dehydrogenase, mitochondrial; EC=1.2.1.3; AltName: Full=ALDH class 2; AltName: Full=ALDH-E2; AltName: Full=ALDH1; Flags: Precursor;
Gene name
Name=Aldh2
Encoded on
Name=Aldh2
Keywords
3D-structure
;
Acetylation
;
Complete proteome
;
Direct protein sequencing
;
Mitochondrion
;
NAD
;
Oxidoreductase
;
Polymorphism
;
Reference proteome
;
Transit peptide
.
Copyright
Copyrighted by the UniProt Consortium, see
https://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
X14977; CAA33101.1
; -; mRNA
EMBL
BC062081; AAH62081.1
; -; mRNA
EMBL
M19030; AAA40719.1
; -; mRNA
EMBL
AY566467; AAS75813.1
; -; mRNA
EMBL
AY566468; AAS75814.1
; -; mRNA
EMBL
AY566469; AAS75815.1
; -; mRNA
EMBL
AF529165; AAM94394.2
; -; mRNA
EMBL
AY034137; AAK57732.1
; -; Genomic_DNA
IPI
IPI00197770; -
; .
PIR
S03564; S03564
; .
RefSeq
NP_115792.1; NM_032416.1
; .
UniGene
Rn.101781; -
; .
PDB
1OM2; NMR
; -; B=12-20
PDB
2V1S; X-ray
; 2.05 A; H/I/J/K/L/M/N=12-20
PDB
2V1T; X-ray
; 1.92 A; C/D=12-22
PDB
3AWR; X-ray
; 2.00 A; C/D=12-20
PDB
3AX2; X-ray
; 1.90 A; B/D/F/H=12-20
PDB
3AX3; X-ray
; 2.10 A; B/D/F/H=14-20
PDB
3AX5; X-ray
; 2.20 A; B/D=14-20
PDBsum
1OM2; -
; .
PDBsum
2V1S; -
; .
PDBsum
2V1T; -
; .
PDBsum
3AWR; -
; .
PDBsum
3AX2; -
; .
PDBsum
3AX3; -
; .
PDBsum
3AX5; -
; .
ProteinModelPortal
P11884; -
; .
SMR
P11884; 26-519
; .
IntAct
P11884; 2
; .
STRING
P11884; -
; .
PhosphoSite
P11884; -
; .
World-2DPAGE
0004:P11884; -
; .
PRIDE
P11884; -
; .
GeneID
29539; -
; .
KEGG
rno:29539; -
; .
CTD
217; -
; .
RGD
69219; Aldh2
; .
eggNOG
maNOG06439; -
; .
HOVERGEN
HBG000097; -
; .
InParanoid
P11884; -
; .
OrthoDB
EOG41ZF9P; -
; .
PhylomeDB
P11884; -
; .
NextBio
609531; -
; .
ArrayExpress
P11884; -
; .
Genevestigator
P11884; -
; .
GermOnline
ENSRNOG00000001344; Rattus norvegicus
; .
GO
GO:0005759; C:mitochondrial matrix
; IEA:UniProtKB-SubCell; .
GO
GO:0004029; F:aldehyde dehydrogenase (NAD) activity
; IDA:RGD; .
GO
GO:0042802; F:identical protein binding
; IDA:RGD; .
GO
GO:0071398; P:cellular response to fatty acid
; IEP:RGD; .
GO
GO:0032870; P:cellular response to hormone stimulus
; IEP:RGD; .
GO
GO:0001889; P:liver development
; IEP:RGD; .
GO
GO:0055093; P:response to hyperoxia
; IEP:RGD; .
GO
GO:0032496; P:response to lipopolysaccharide
; IEP:RGD; .
GO
GO:0035094; P:response to nicotine
; IEP:RGD; .
GO
GO:0032570; P:response to progesterone stimulus
; IEP:RGD; .
GO
GO:0033574; P:response to testosterone stimulus
; IEP:RGD; .
InterPro
IPR016161; Ald_DH/histidinol_DH
; .
InterPro
IPR016163; Ald_DH_C
; .
InterPro
IPR016160; Ald_DH_CS
; .
InterPro
IPR016162; Ald_DH_N
; .
InterPro
IPR015590; Aldehyde_DH_dom
; .
Gene3D
G3DSA:3.40.309.10; Aldehyde_dehydrogenase_C
; 1; .
Gene3D
G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N
; 1; .
KO
K00128; -
; .
Pfam
PF00171; Aldedh
; 1; .
SUPFAM
SSF53720; Aldehyde_DH/Histidinol_DH
; 1; .
PROSITE
PS00070; ALDEHYDE_DEHYDR_CYS
; 1; .
PROSITE
PS00687; ALDEHYDE_DEHYDR_GLU
; 1; .
World-2DPAGE Repository (search AC)
Database constructed and maintained by
SIB
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
Expasy web server