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Searching in 'World-2DPAGE Repository [0022]' for entry matching: P11884 World-2DPAGE Repository (0022):  P11884 P11884 General information about the entry View entry in simple text format Entry name ALDH2_RAT Primary accession number P11884 integrated into World-2DPAGE Repository (0022) on  May 7, 2010 (release 1) 2D Annotations were last modified on June 22, 2011 (version 2) General Annotations were last modified on  November 24, 2011 (version 2) Name and origin of the protein Description RecName: Full=Aldehyde dehydrogenase, mitochondrial; EC=1.2.1.3; AltName: Full=ALDH class 2; AltName: Full=ALDH-E2; AltName: Full=ALDH1; Flags: Precursor;. Gene name Name=Aldh2 Annotated species Rattus [TaxID: 10114] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000593; Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L. ''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity'' Proteomics 11(16):3369-3379 (2011) 2D PAGE maps for identified proteins How to interpret a protein HCR_LCR_HEART {HCR LCR Cardiac Map} Rattus Tissue: Heart   map experimental info   HCR_LCR_HEART MAP LOCATIONS: SPOT 124: pI=6.63; Mw=56966   [identification data] SPOT 244: pI=6.63; Mw=56966   [identification data] SPOT 599: pI=6.63; Mw=56966   [identification data] IDENTIFICATION: SPOT 124: SeqCov=21.4%. Peptides MS=9/20. Mascot PMF Score=69 [1] SPOT 244: SeqCov=27.7%. Peptides MS=14/20. Mascot PMF Score=126 [1]; SPOT 599: SeqCov=14.5%. Peptides MS=8/20. Mascot PMF Score=46 [1]. PEPTIDE EVIDENCE: SPOT 124: 397-GYFIQPTVFGDVK-409 (34) / 162-TIPIDGDFFSYTR-174 (88) / 327-TFVQEDVYDEFVER-340 (87) [1] SPOT 599: 162-TIPIDGDFFSYTR-174 (98) / 327-TFVQEDVYDEFVER-340 (91) [1]. MAPPING (identification): SPOT 124: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 244: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 599: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Jatin Burniston, Liverpool John Moores University, UK Cross-references UniProtKB/Swiss-Prot P11884; ALDH2_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name ALDH2_RAT Primary accession number P11884 Secondary accession number(s) Q6Q288 Q6Q289 Q6Q290 Q8K3V8 Q91ZD7 Sequence was last modified on  October 1, 1989 (version 1) Annotations were last modified on  November 16, 2011 (version 115) Name and origin of the protein Description RecName: Full=Aldehyde dehydrogenase, mitochondrial; EC=1.2.1.3; AltName: Full=ALDH class 2; AltName: Full=ALDH-E2; AltName: Full=ALDH1; Flags: Precursor; Gene name Name=Aldh2 Encoded on Name=Aldh2 Keywords 3D-structure; Acetylation; Complete proteome; Direct protein sequencing; Mitochondrion; NAD; Oxidoreductase; Polymorphism; Reference proteome; Transit peptide. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X14977; CAA33101.1; -; mRNA EMBL BC062081; AAH62081.1; -; mRNA EMBL M19030; AAA40719.1; -; mRNA EMBL AY566467; AAS75813.1; -; mRNA EMBL AY566468; AAS75814.1; -; mRNA EMBL AY566469; AAS75815.1; -; mRNA EMBL AF529165; AAM94394.2; -; mRNA EMBL AY034137; AAK57732.1; -; Genomic_DNA IPI IPI00197770; -; . PIR S03564; S03564; . RefSeq NP_115792.1; NM_032416.1; . UniGene Rn.101781; -; . PDB 1OM2; NMR; -; B=12-20 PDB 2V1S; X-ray; 2.05 A; H/I/J/K/L/M/N=12-20 PDB 2V1T; X-ray; 1.92 A; C/D=12-22 PDB 3AWR; X-ray; 2.00 A; C/D=12-20 PDB 3AX2; X-ray; 1.90 A; B/D/F/H=12-20 PDB 3AX3; X-ray; 2.10 A; B/D/F/H=14-20 PDB 3AX5; X-ray; 2.20 A; B/D=14-20 PDBsum 1OM2; -; . PDBsum 2V1S; -; . PDBsum 2V1T; -; . PDBsum 3AWR; -; . PDBsum 3AX2; -; . PDBsum 3AX3; -; . PDBsum 3AX5; -; . ProteinModelPortal P11884; -; . SMR P11884; 26-519; . IntAct P11884; 2; . STRING P11884; -; . PhosphoSite P11884; -; . World-2DPAGE 0004:P11884; -; . PRIDE P11884; -; . GeneID 29539; -; . KEGG rno:29539; -; . CTD 217; -; . RGD 69219; Aldh2; . eggNOG maNOG06439; -; . HOVERGEN HBG000097; -; . InParanoid P11884; -; . OrthoDB EOG41ZF9P; -; . PhylomeDB P11884; -; . NextBio 609531; -; . ArrayExpress P11884; -; . Genevestigator P11884; -; . GermOnline ENSRNOG00000001344; Rattus norvegicus; . GO GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell; . GO GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IDA:RGD; . GO GO:0042802; F:identical protein binding; IDA:RGD; . GO GO:0071398; P:cellular response to fatty acid; IEP:RGD; . GO GO:0032870; P:cellular response to hormone stimulus; IEP:RGD; . GO GO:0001889; P:liver development; IEP:RGD; . GO GO:0055093; P:response to hyperoxia; IEP:RGD; . GO GO:0032496; P:response to lipopolysaccharide; IEP:RGD; . GO GO:0035094; P:response to nicotine; IEP:RGD; . GO GO:0032570; P:response to progesterone stimulus; IEP:RGD; . GO GO:0033574; P:response to testosterone stimulus; IEP:RGD; . InterPro IPR016161; Ald_DH/histidinol_DH; . InterPro IPR016163; Ald_DH_C; . InterPro IPR016160; Ald_DH_CS; . InterPro IPR016162; Ald_DH_N; . InterPro IPR015590; Aldehyde_DH_dom; . Gene3D G3DSA:3.40.309.10; Aldehyde_dehydrogenase_C; 1; . Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1; . KO K00128; -; . Pfam PF00171; Aldedh; 1; . SUPFAM SSF53720; Aldehyde_DH/Histidinol_DH; 1; . PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; 1; . PROSITE PS00687; ALDEHYDE_DEHYDR_GLU; 1; . World-2DPAGE Repository (search AC)