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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0022]' for entry matching: P12007 World-2DPAGE Repository (0022):  P12007 P12007 General information about the entry View entry in simple text format Entry name IVD_RAT Primary accession number P12007 integrated into World-2DPAGE Repository (0022) on  May 7, 2010 (release 1) 2D Annotations were last modified on June 22, 2011 (version 2) General Annotations were last modified on  November 24, 2011 (version 2) Name and origin of the protein Description RecName: Full=Isovaleryl-CoA dehydrogenase, mitochondrial; Short=IVD; EC=1.3.99.10; Flags: Precursor;. Gene name Name=Ivd Annotated species Rattus [TaxID: 10114] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000593; Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L. ''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity'' Proteomics 11(16):3369-3379 (2011) 2D PAGE maps for identified proteins How to interpret a protein HCR_LCR_HEART {HCR LCR Cardiac Map} Rattus Tissue: Heart   map experimental info   HCR_LCR_HEART MAP LOCATIONS: SPOT 168: pI=8.03; Mw=46862   [identification data] SPOT 315: pI=8.03; Mw=46862   [identification data] SPOT 567: pI=8.03; Mw=46862   [identification data] IDENTIFICATION: SPOT 168: SeqCov=32.8%. Peptides MS=13/20. Mascot PMF Score=125 [1] SPOT 315: SeqCov=17.9%. Peptides MS=7/20. Mascot PMF Score=52 [1]; SPOT 567: SeqCov=26.9%. Peptides MS=8/20. Mascot PMF Score=68 [1]. PEPTIDE EVIDENCE: SPOT 567: 418-AFNADFR-424 (52) / 339-QYVYNVAR-346 (30) / 119-ASAAVGLSYGAHSNLCINQIVR-140 (66) [1]. MAPPING (identification): SPOT 168: Peptide mass fingerprinting [1]; SPOT 315: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 567: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Jatin Burniston, Liverpool John Moores University, UK Cross-references UniProtKB/Swiss-Prot P12007; IVD_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name IVD_RAT Primary accession number P12007 Sequence was last modified on  April 1, 1990 (version 2) Annotations were last modified on  November 16, 2011 (version 111) Name and origin of the protein Description RecName: Full=Isovaleryl-CoA dehydrogenase, mitochondrial; Short=IVD; EC=1.3.99.10; Flags: Precursor; Gene name Name=Ivd Encoded on Name=Ivd Keywords Acetylation; Complete proteome; Direct protein sequencing; FAD; Flavoprotein; Mitochondrion; Oxidoreductase; Reference proteome; Transit peptide. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL J05031; AAA41454.1; -; mRNA EMBL BC088401; AAH88401.1; -; mRNA EMBL M19867; AAA41459.1; -; mRNA IPI IPI00193716; -; . PIR C34252; C34252; . RefSeq NP_036724.1; NM_012592.2; . UniGene Rn.147; -; . ProteinModelPortal P12007; -; . SMR P12007; 36-422; . STRING P12007; -; . PRIDE P12007; -; . Ensembl ENSRNOT00000013829; ENSRNOP00000013829; ENSRNOG00000009421; . GeneID 24513; -; . KEGG rno:24513; -; . NMPDR fig|10116.3.peg.19461; -; . UCSC NM_012592; rat; . CTD 3712; -; . RGD 2936; Ivd; . eggNOG roNOG10079; -; . GeneTree ENSGT00590000082906; -; . HOVERGEN HBG000224; -; . InParanoid P12007; -; . OMA DLDKGAH; -; . OrthoDB EOG4RR6HF; -; . PhylomeDB P12007; -; . NextBio 603537; -; . ArrayExpress P12007; -; . Genevestigator P12007; -; . GermOnline ENSRNOG00000009421; Rattus norvegicus; . GO GO:0005759; C:mitochondrial matrix; IDA:BHF-UCL; . GO GO:0031966; C:mitochondrial membrane; IDA:BHF-UCL; . GO GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro; . GO GO:0008470; F:isovaleryl-CoA dehydrogenase activity; IDA:BHF-UCL; . GO GO:0033539; P:fatty acid beta-oxidation using acyl-CoA dehydrogenase; IC:BHF-UCL; . GO GO:0006552; P:leucine catabolic process; IDA:BHF-UCL; . GO GO:0051260; P:protein homooligomerization; TAS:RGD; . InterPro IPR006089; Acyl-CoA_DH_CS; . InterPro IPR006092; Acyl-CoA_DH_N; . InterPro IPR006090; Acyl-CoA_Oxase/DH_1; . InterPro IPR006091; Acyl-CoA_Oxase/DH_cen-dom; . InterPro IPR009075; AcylCo_DH/oxidase_C; . InterPro IPR013786; AcylCoA_DH/ox_N; . InterPro IPR009100; AcylCoA_DH/oxidase; . Gene3D G3DSA:2.40.110.10; Acyl_CoA_DH/ox_M; 1; . Gene3D G3DSA:1.10.540.10; AcylCoA_DH/ox_N; 1; . Gene3D G3DSA:1.20.140.10; AcylCoA_DH_1/2_C; 1; . KO K00253; -; . Pfam PF00441; Acyl-CoA_dh_1; 1; . Pfam PF02770; Acyl-CoA_dh_M; 1; . Pfam PF02771; Acyl-CoA_dh_N; 1; . SUPFAM SSF56645; AcylCoA_dehyd_NM; 1; . SUPFAM SSF47203; AcylCoADH_C_like; 1; . PROSITE PS00072; ACYL_COA_DH_1; 1; . PROSITE PS00073; ACYL_COA_DH_2; 1; . World-2DPAGE Repository (search AC)