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Searching in 'World-2DPAGE Repository [0043]' for entry matching: P14602

World-2DPAGE Repository (0043):  P14602


General information about the entry
View entry in simple text format
Entry nameHSPB1_MOUSE
Primary accession numberP14602
integrated into World-2DPAGE Repository (0043) on January 4, 2012 (release 1)
2D Annotations were last modified onJanuary 6, 2012 (version 1)
General Annotations were last modified on April 18, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Heat shock protein beta-1; Short=HspB1; AltName: Full=Growth-related 25 kDa protein; AltName: Full=Heat shock 25 kDa protein; Short=HSP 25; AltName: Full=Heat shock 27 kDa protein; Short=HSP 27; AltName: Full=p25;.
Gene nameName=Hspb1
Synonyms=Hsp25, Hsp27
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
DOI=10.1016/j.jprot.2012.04.001 ;
Sun Z., Biela L.M., Hamilton K.L., Reardon K.F.
''Concentration-dependent effects of the soy phytoestrogen genistein on the proteome of cultured cardiomyocytes''
Journal of Proteomics 0(0):0-0 (2012)
2D PAGE maps for identified proteins
How to interpret a protein

MMUSCULUS_HL-1PHI_4-7 {mouse HL-1 cultured cardiomyocytes hydrophilic extraction}
Mus musculus (Mouse)
Tissue: Cardiac myocyte
  map experimental info

Mw=23057  [identification data]
Mw=23057  [identification data]
Mw=23057  [identification data]

%COV: BAND phi32: 17.6 [1]
BAND phi63: 17.3 [1]; BAND phi65: 27.6 [1].
BAND phi63: HSPB1_MOUSE [1]; BAND phi65: HSPB1_MOUSE [1].
SCORE: BAND phi32: 1071 [1]
BAND phi63: 273 [1]; BAND phi65: 187 [1].
SEARCH ENGINE: BAND phi32: Mascot [1]
BAND phi63: Mascot [1]; BAND phi65: Mascot [1].
MAPPING (identification):
BAND phi32: Tandem mass spectrometry [1];
BAND phi63: Tandem mass spectrometry [1];
BAND phi65: Tandem mass spectrometry [1].

MMUSCULUS_HL-1PHO_4-7 {mouse HL-1 cultured cardiomyocytes hydrophobic extraction}
Mus musculus (Mouse)
Tissue: Cardiac myocyte
  map experimental info

Mw=23057  [identification data]

%COV: BAND pho32: 10 [1].
SCORE: BAND pho32: 86 [1].
SEARCH ENGINE: BAND pho32: Mascot [1].
MAPPING (identification):
BAND pho32: Tandem mass spectrometry [1].

Data from Dr. Zeyu Sun, Department of Chemical and Biological Engineering, Colorado State University, Fort Collins, USA
UniProtKB/Swiss-ProtP14602; HSPB1_MOUSE.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2012_03
Entry nameHSPB1_MOUSE
Primary accession numberP14602
Sequence was last modified on June 1, 1994 (version 3)
Annotations were last modified on March 21, 2012 (version 127)
Name and origin of the protein
DescriptionRecName: Full=Heat shock protein beta-1; Short=HspB1; AltName: Full=Growth-related 25 kDa protein; AltName: Full=Heat shock 25 kDa protein; Short=HSP 25; AltName: Full=Heat shock 27 kDa protein; Short=HSP 27; AltName: Full=p25;
Gene nameName=Hspb1
Synonyms=Hsp25, Hsp27
Encoded onName=Hspb1; Synonyms=Hsp25, Hsp27
KeywordsAcetylation; Alternative splicing; Chaperone; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Nucleus; Phosphoprotein; Reference proteome; Stress response.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLX14687; CAA32818.1; -; mRNA
EMBLX14686; CAB37341.1; -; mRNA
EMBLL11609; AAA37862.1; -; Genomic_DNA
EMBLL11608; AAA37862.1; JOINED; Genomic_DNA
EMBLL07577; AAA37861.1; -; Genomic_DNA
EMBLU03560; AAA18335.1; -; mRNA
EMBLU03561; AAA18336.1; -; mRNA
EMBLU03562; AAA18337.1; -; mRNA
EMBLBC018257; AAH18257.1; -; mRNA
IPIIPI00128522; -; .
IPIIPI00468068; -; .
IPIIPI00623819; -; .
PIRA53423; A53423; .
PIRI49763; JN0679; .
PIRS02143; S02143; .
RefSeqNP_038588.2; NM_013560.2; .
UniGeneMm.13849; -; .
ProteinModelPortalP14602; -; .
SMRP14602; 17-198; .
DisProtDP00142; -; .
IntActP14602; 6; .
STRINGP14602; -; .
PhosphoSiteP14602; -; .
SWISS-2DPAGEP14602; -; .
UCD-2DPAGEP14602; -; .
PRIDEP14602; -; .
EnsemblENSMUST00000005077; ENSMUSP00000005077; ENSMUSG00000004951; .
EnsemblENSMUST00000111156; ENSMUSP00000106786; ENSMUSG00000004951; .
GeneID15507; -; .
KEGGmmu:15507; -; .
CTD3315; -; .
MGIMGI:96240; Hspb1; .
eggNOGNOG307785; -; .
GeneTreeENSGT00550000074302; -; .
HOGENOMHBG748242; -; .
HOVERGENHBG054766; -; .
InParanoidP14602; -; .
KOK04455; -; .
OrthoDBEOG4DR9DF; -; .
PhylomeDBP14602; -; .
NextBio288412; -; .
ArrayExpressP14602; -; .
BgeeP14602; -; .
CleanExMM_HSPB1; -; .
GenevestigatorP14602; -; .
GermOnlineENSMUSG00000004951; Mus musculus; .
GOGO:0009986; C:cell surface; ISS:BHF-UCL; .
GOGO:0005626; C:insoluble fraction; IDA:MGI; .
GOGO:0005634; C:nucleus; IDA:MGI; .
GOGO:0005886; C:plasma membrane; IDA:MGI; .
GOGO:0000502; C:proteasome complex; ISS:BHF-UCL; .
GOGO:0005625; C:soluble fraction; IDA:MGI; .
GOGO:0005819; C:spindle; IEA:UniProtKB-SubCell; .
GOGO:0030018; C:Z disc; IDA:MGI; .
GOGO:0005080; F:protein kinase C binding; IDA:BHF-UCL; .
GOGO:0008426; F:protein kinase C inhibitor activity; IDA:BHF-UCL; .
GOGO:0043130; F:ubiquitin binding; ISS:BHF-UCL; .
GOGO:0043066; P:negative regulation of apoptotic process; IDA:BHF-UCL; .
GOGO:0032731; P:positive regulation of interleukin-1 beta production; IDA:BHF-UCL; .
GOGO:0042535; P:positive regulation of tumor necrosis factor biosynthetic process; IDA:BHF-UCL; .
GOGO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IDA:BHF-UCL; .
GOGO:0006986; P:response to unfolded protein; NAS:BHF-UCL; .
GOGO:0009615; P:response to virus; ISS:BHF-UCL; .
InterProIPR001436; Alpha-crystallin/HSP; .
InterProIPR002068; Hsp20; .
InterProIPR008978; HSP20-like_chaperone; .
PfamPF00011; HSP20; 1; .
PIRSFPIRSF036514; Sm_HSP_B1; 1; .
SUPFAMSSF49764; HSP20_chap; 1; .
PROSITEPS01031; HSP20; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server