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Searching in 'World-2DPAGE Repository [0014]' for entry matching: P16086




World-2DPAGE Repository (0014):  P16086

P16086


General information about the entry
View entry in simple text format
Entry nameSPTA2_RAT
Primary accession numberP16086
integrated into World-2DPAGE Repository (0014) on October 13, 2008 (release 1)
2D Annotations were last modified onJune 1, 2011 (version 3)
General Annotations were last modified on November 25, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Spectrin alpha chain, brain; AltName: Full=Alpha-II spectrin; AltName: Full=Fodrin alpha chain; AltName: Full=Spectrin, non-erythroid alpha chain;.
Gene nameName=Sptan1
Synonyms=Spna2, Spta2
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/pmic.200900680;
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of whole cerebellum of the mature rat''
Proteomics 10(23):4311-4319 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_CEREBELLUM_21D {Proteome of 21 days old rat cerebellum}
Rattus norvegicus (Rat)
Tissue: Cerebellum
RAT_CEREBELLUM_21D
  map experimental info 		 
RAT_CEREBELLUM_21D

MAP LOCATIONS:
pI=5.19; Mw=285000  [identification data]

IDENTIFICATION: SPOT 2601: SeqCov=25%. MascotPMF=482 [1].
MAPPING (identification):
SPOT 2601: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
Cross-references
PRIDE10017.
UniProtKB/Swiss-ProtP16086; SPTA2_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameSPTA2_RAT
Primary accession numberP16086
Secondary accession number(s) O88663 P70477
Sequence was last modified on November 16, 2001 (version 2)
Annotations were last modified on November 16, 2011 (version 120)
Name and origin of the protein
DescriptionRecName: Full=Spectrin alpha chain, brain; AltName: Full=Alpha-II spectrin; AltName: Full=Fodrin alpha chain; AltName: Full=Spectrin, non-erythroid alpha chain;
Gene nameName=Sptan1
Synonyms=Spna2, Spta2
Encoded onName=Sptan1; Synonyms=Spna2, Spta2
KeywordsAcetylation; Actin capping; Actin-binding; Calcium; Calmodulin-binding; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Phosphoprotein; Reference proteome; Repeat; SH3 domain.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX90845; CAA62350.1; -; mRNA
EMBLAF084186; AAC33127.1; -; mRNA
EMBLJ04828; AAA40770.1; ALT_FRAME; mRNA
IPIIPI00776619; -; .
PIRA32612; A32612; .
PIRS61217; S61217; .
RefSeqNP_741984.2; NM_171983.2; .
UniGeneRn.5812; -; .
ProteinModelPortalP16086; -; .
SMRP16086; 2-147; 967-1025; 1445-1549
1657-1974.
MINTMINT-4996484; -; .
STRINGP16086; -; .
PhosphoSiteP16086; -; .
PRIDEP16086; -; .
EnsemblENSRNOT00000060787; ENSRNOP00000057515; ENSRNOG00000015396; .
GeneID64159; -; .
KEGGrno:64159; -; .
UCSCBC070885; rat; .
CTD6709; -; .
RGD621714; Spna2; .
eggNOGmaNOG10362; -; .
HOVERGENHBG059266; -; .
InParanoidP16086; -; .
NextBio612802; -; .
ArrayExpressP16086; -; .
GenevestigatorP16086; -; .
GermOnlineENSRNOG00000015396; Rattus norvegicus; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0005886; C:plasma membrane; IDA:RGD; .
GOGO:0043234; C:protein complex; IDA:RGD; .
GOGO:0008091; C:spectrin; TAS:RGD; .
GOGO:0003779; F:actin binding; IEA:UniProtKB-KW; .
GOGO:0005509; F:calcium ion binding; IEA:InterPro; .
GOGO:0005516; F:calmodulin binding; IEA:UniProtKB-KW; .
GOGO:0032403; F:protein complex binding; IPI:RGD; .
GOGO:0047485; F:protein N-terminus binding; IPI:RGD; .
GOGO:0019905; F:syntaxin binding; IPI:RGD; .
GOGO:0031532; P:actin cytoskeleton reorganization; IMP:RGD; .
GOGO:0051693; P:actin filament capping; IEA:UniProtKB-KW; .
InterProIPR018248; EF-hand; .
InterProIPR011992; EF-hand-like_dom; .
InterProIPR014837; EF-hand_Ca_insen; .
InterProIPR018247; EF_Hand_1_Ca_BS; .
InterProIPR018249; EF_HAND_2; .
InterProIPR002048; EF_hand_Ca-bd; .
InterProIPR001452; SH3_domain; .
InterProIPR018159; Spectrin/alpha-actinin; .
InterProIPR013315; Spectrin_alpha_SH3; .
InterProIPR002017; Spectrin_repeat; .
Gene3DG3DSA:1.10.238.10; EF-Hand_type; 2; .
KOK06114; -; .
PfamPF00036; efhand; 1; .
PfamPF08726; efhand_Ca_insen; 1; .
PfamPF00018; SH3_1; 1; .
PfamPF00435; Spectrin; 20; .
PRINTSPR00452; SH3DOMAIN; .
PRINTSPR01887; SPECTRNALPHA; .
SMARTSM00054; EFh; 2; .
SMARTSM00326; SH3; 1; .
SMARTSM00150; SPEC; 20; .
SUPFAMSSF50044; SH3; 1; .
PROSITEPS00018; EF_HAND_1; 2; .
PROSITEPS50222; EF_HAND_2; 3; .
PROSITEPS50002; SH3; 1; .


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