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Searching in 'World-2DPAGE Repository [0030]' for entry matching: P18418

World-2DPAGE Repository (0030):  P18418


General information about the entry
View entry in simple text format
Entry nameCALR_RAT
Primary accession numberP18418
integrated into World-2DPAGE Repository (0030) on November 9, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Calreticulin; AltName: Full=CALBP; AltName: Full=CRP55; AltName: Full=Calcium-binding protein 3; Short=CABP3; AltName: Full=Calregulin; AltName: Full=Endoplasmic reticulum resident protein 60; Short=ERp60; AltName: Full=HACBP; Flags: Precursor;.
Gene nameName=Calr
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C.
''Two-dimensional gel proteome reference map of INS-1E cells''
Proteomics 11(7):1365-1369 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7}
Rattus norvegicus (Rat)
  map experimental info

pI=4.60; Mw=72893  [identification data]
pI=4.55; Mw=71693  [identification data]
pI=4.79; Mw=71693  [identification data]
pI=4.24; Mw=71199  [identification data]
pI=4.26; Mw=68779  [identification data]

IDENTIFICATION: SPOT 714: Mascot protein score=63. Number of peptides=3 [1]
SPOT 732: Mascot protein score=323. Number of peptides=7 [1]; SPOT 743: Mascot protein score=406. Number of peptides=7 [1]; SPOT 757: Mascot protein score=83. Number of peptides=3 [1]; SPOT 813: Mascot protein score=147. Number of peptides=5 [1].
MAPPING (identification):
SPOT 714: Tandem mass spectrometry [1];
SPOT 732: Tandem mass spectrometry [1];
SPOT 743: Tandem mass spectrometry [1];
SPOT 757: Tandem mass spectrometry [1];
SPOT 813: Tandem mass spectrometry [1].

Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium
UniProtKB/Swiss-ProtP18418; CALR_RAT.
World-2DPAGE RepositoryP18418; CALR_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameCALR_RAT
Primary accession numberP18418
Secondary accession number(s) P10452
Sequence was last modified on November 1, 1990 (version 1)
Annotations were last modified on November 16, 2011 (version 124)
Name and origin of the protein
DescriptionRecName: Full=Calreticulin; AltName: Full=CALBP; AltName: Full=CRP55; AltName: Full=Calcium-binding protein 3; Short=CABP3; AltName: Full=Calregulin; AltName: Full=Endoplasmic reticulum resident protein 60; Short=ERp60; AltName: Full=HACBP; Flags: Precursor;
Gene nameName=Calr
Encoded onName=Calr
Keywords3D-structure; Acetylation; Calcium; Chaperone; Complete proteome; Direct protein sequencing; Disulfide bond; Endoplasmic reticulum; Lectin; Metal-binding; Reference proteome; Repeat; Signal; Zinc.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLX53363; CAA37446.1; -; mRNA
EMBLD78308; BAA11345.1; -; mRNA
EMBLX79327; CAA55890.1; -; mRNA
EMBLBC062395; AAH62395.1; -; mRNA
EMBLX13702; CAA31987.1; -; mRNA
IPIIPI00191728; -; .
PIRJH0819; JH0819; .
RefSeqNP_071794.1; NM_022399.2; .
UniGeneRn.974; -; .
PDB1HHN; NMR; -; A=206-305
PDB1K91; NMR; -; A=238-273
PDB1K9C; NMR; -; A=206-278
PDBsum1HHN; -; .
PDBsum1K91; -; .
PDBsum1K9C; -; .
ProteinModelPortalP18418; -; .
SMRP18418; 206-305; .
IntActP18418; 2; .
STRINGP18418; -; .
World-2DPAGE0004:P18418; -; .
PRIDEP18418; -; .
EnsemblENSRNOT00000004091; ENSRNOP00000004091; ENSRNOG00000003029; .
GeneID64202; -; .
KEGGrno:64202; -; .
UCSCNM_022399; rat; .
CTD811; -; .
RGD620288; Calr; .
eggNOGroNOG10495; -; .
GeneTreeENSGT00430000030841; -; .
HOVERGENHBG005407; -; .
InParanoidP18418; -; .
OrthoDBEOG41JZCD; -; .
PhylomeDBP18418; -; .
NextBio612898; -; .
ArrayExpressP18418; -; .
GenevestigatorP18418; -; .
GermOnlineENSRNOG00000003029; Rattus norvegicus; .
GOGO:0001669; C:acrosomal vesicle; IDA:RGD; .
GOGO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell; .
GOGO:0031012; C:extracellular matrix; IDA:RGD; .
GOGO:0005615; C:extracellular space; IDA:RGD; .
GOGO:0005794; C:Golgi apparatus; IDA:RGD; .
GOGO:0005792; C:microsome; IDA:RGD; .
GOGO:0005634; C:nucleus; IDA:RGD; .
GOGO:0048471; C:perinuclear region of cytoplasm; IDA:RGD; .
GOGO:0016529; C:sarcoplasmic reticulum; IDA:RGD; .
GOGO:0005625; C:soluble fraction; IDA:RGD; .
GOGO:0005509; F:calcium ion binding; IDA:RGD; .
GOGO:0042562; F:hormone binding; IPI:RGD; .
GOGO:0005506; F:iron ion binding; IDA:RGD; .
GOGO:0003729; F:mRNA binding; IDA:BHF-UCL; .
GOGO:0042277; F:peptide binding; IDA:RGD; .
GOGO:0005529; F:sugar binding; IEA:UniProtKB-KW; .
GOGO:0051082; F:unfolded protein binding; IEA:InterPro; .
GOGO:0055007; P:cardiac muscle cell differentiation; IEP:RGD; .
GOGO:0071285; P:cellular response to lithium ion; IEP:RGD; .
GOGO:0071310; P:cellular response to organic substance; IEP:RGD; .
GOGO:0017148; P:negative regulation of translation; IDA:BHF-UCL; .
GOGO:0006457; P:protein folding; TAS:RGD; .
GOGO:0050821; P:protein stabilization; ISS:UniProtKB; .
GOGO:0042493; P:response to drug; IEP:RGD; .
GOGO:0032355; P:response to estradiol stimulus; IEP:RGD; .
GOGO:0033574; P:response to testosterone stimulus; IEP:RGD; .
GOGO:0007283; P:spermatogenesis; IEP:RGD; .
InterProIPR001580; Calret/calnex; .
InterProIPR018124; Calret/calnex_CS; .
InterProIPR009169; Calreticulin; .
InterProIPR008985; ConA-like_lec_gl; .
InterProIPR013320; ConA-like_subgrp; .
Gene3DG3DSA:; ConA_like_subgrp; 2; .
KOK08057; -; .
PANTHERPTHR11073; Calret/calnex; 1; .
PfamPF00262; Calreticulin; 1; .
PIRSFPIRSF002356; Calreticulin; 1; .
SUPFAMSSF49899; ConA_like_lec_gl; 2; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server