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Searching in 'World-2DPAGE Repository [0019]' for entry matching: P18420




World-2DPAGE Repository (0019):  P18420


P18420


General information about the entry
View entry in simple text format
Entry namePSA1_RAT
Primary accession numberP18420
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Proteasome subunit alpha type-1; EC=3.4.25.1; AltName: Full=Macropain subunit C2; AltName: Full=Multicatalytic endopeptidase complex subunit C2; AltName: Full=Proteasome component C2; AltName: Full=Proteasome nu chain;.
Gene nameName=Psma1
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1111/j.1471-4159.2010.06719.x;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
HIPP_SYNAP
  map experimental info
 
HIPP_SYNAP

MAP LOCATIONS:
pI=6.14; Mw=29517  [identification data]
pI=6.15; Mw=29783  [identification data]

IDENTIFICATION: SPOT 712: Peptides number=23. SeqCov=86.3%. MOWSE score=6.30E+27 [1]
SPOT 1077: Peptides number=4. SeqCov=20.2%. MOWSE score=3.36E+6 [1].
MAPPING (identification):
SPOT 712: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1077: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-ProtP18420; PSA1_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry namePSA1_RAT
Primary accession numberP18420
Sequence was last modified on February 1, 1991 (version 2)
Annotations were last modified on November 16, 2011 (version 106)
Name and origin of the protein
DescriptionRecName: Full=Proteasome subunit alpha type-1; EC=3.4.25.1; AltName: Full=Macropain subunit C2; AltName: Full=Multicatalytic endopeptidase complex subunit C2; AltName: Full=Proteasome component C2; AltName: Full=Proteasome nu chain;
Gene nameName=Psma1
Encoded onName=Psma1
KeywordsAcetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Hydrolase; Immunity; Isopeptide bond; Nucleus; Phosphoprotein; Protease; Proteasome; Reference proteome; Threonine protease; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM29859; AAA41943.1; -; mRNA
EMBLD90265; BAA14312.1; -; mRNA
EMBLBC062233; AAH62233.1; -; mRNA
IPIIPI00191748; -; .
PIRA32968; SNRTC2; .
RefSeqNP_058974.1; NM_017278.1; .
UniGeneRn.2668; -; .
ProteinModelPortalP18420; -; .
SMRP18420; 4-241; .
IntActP18420; 1; .
STRINGP18420; -; .
MEROPST01.976; -; .
World-2DPAGE0004:P18420; -; .
PRIDEP18420; -; .
EnsemblENSRNOT00000015946; ENSRNOP00000015946; ENSRNOG00000011745; .
GeneID29668; -; .
KEGGrno:29668; -; .
NMPDRfig|10116.3.peg.2814; -; .
UCSCNM_017278; rat; .
CTD5682; -; .
RGD61841; Psma1; .
eggNOGroNOG10559; -; .
GeneTreeENSGT00550000074855; -; .
HOVERGENHBG105373; -; .
InParanoidP18420; -; .
OrthoDBEOG4S1T7S; -; .
PhylomeDBP18420; -; .
NextBio609983; -; .
ArrayExpressP18420; -; .
GenevestigatorP18420; -; .
GermOnlineENSRNOG00000011745; Rattus norvegicus; .
GOGO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell; .
GOGO:0005634; C:nucleus; IEA:UniProtKB-SubCell; .
GOGO:0019773; C:proteasome core complex; alpha-subunit complex; IEA:InterPro
GOGO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW; .
GOGO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro; .
InterProIPR000426; Proteasome_asu_CS; .
InterProIPR023332; Proteasome_suA-type; .
InterProIPR001353; Proteasome_sua/b; .
KOK02725; -; .
PfamPF00227; Proteasome; 1; .
PfamPF10584; Proteasome_A_N; 1; .
SMARTSM00948; Proteasome_A_N; 1; .
PROSITEPS00388; PROTEASOME_A_1; 1; .
PROSITEPS51475; PROTEASOME_A_2; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server