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Searching in 'World-2DPAGE Repository [0019]' for entry matching: P19804




World-2DPAGE Repository (0019):  P19804

P19804


General information about the entry
View entry in simple text format
Entry nameNDKB_RAT
Primary accession numberP19804
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Nucleoside diphosphate kinase B; Short=NDK B; Short=NDP kinase B; EC=2.7.4.6; AltName: Full=Histidine protein kinase NDKB; EC=2.7.13.3; AltName: Full=P18;.
Gene nameName=Nme2
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1111/j.1471-4159.2010.06719.x;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
HIPP_SYNAP
  map experimental info 		 
HIPP_SYNAP

MAP LOCATIONS:
pI=6.92; Mw=17385  [identification data]
pI=6.92; Mw=17385  [identification data]

IDENTIFICATION: SPOT 891: Peptides number=6. SeqCov=50.7%. MOWSE score=8.92E+5 [1]
SPOT 901: Peptides number=3. SeqCov=19.1%. MOWSE score=1.02E+2 [1].
MAPPING (identification):
SPOT 891: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 901: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-ProtP19804; NDKB_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameNDKB_RAT
Primary accession numberP19804
Sequence was last modified on February 1, 1991 (version 1)
Annotations were last modified on November 16, 2011 (version 110)
Name and origin of the protein
DescriptionRecName: Full=Nucleoside diphosphate kinase B; Short=NDK B; Short=NDP kinase B; EC=2.7.4.6; AltName: Full=Histidine protein kinase NDKB; EC=2.7.13.3; AltName: Full=P18;
Gene nameName=Nme2
Encoded onName=Nme2
KeywordsAcetylation; ATP-binding; Cell membrane; Complete proteome; Cytoplasm; Direct protein sequencing; Kinase; Magnesium; Membrane; Metal-binding; Nucleotide metabolism; Nucleotide-binding; Phosphoprotein; Reference proteome; Transferase.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM55331; AAA41684.1; -; mRNA
EMBLM91597; AAA42017.1; -; mRNA
EMBLBC086599; AAH86599.1; -; mRNA
IPIIPI00325189; -; .
PIRA41849; A38369; .
RefSeqNP_114021.2; NM_031833.2; .
UniGeneRn.927; -; .
ProteinModelPortalP19804; -; .
SMRP19804; 2-152; .
IntActP19804; 1; .
MINTMINT-233154; -; .
STRINGP19804; -; .
PhosphoSiteP19804; -; .
World-2DPAGE0004:P19804; -; .
PRIDEP19804; -; .
EnsemblENSRNOT00000003611; ENSRNOP00000003611; ENSRNOG00000002671; .
GeneID83782; -; .
KEGGrno:83782; -; .
NMPDRfig|10116.3.peg.5894; -; .
UCSCNM_031833; rat; .
CTD4831; -; .
RGD619877; Nme2; .
eggNOGroNOG13226; -; .
HOVERGENHBG000423; -; .
InParanoidP19804; -; .
OMAMVWEGRD; -; .
OrthoDBEOG4S1T8G; -; .
PhylomeDBP19804; -; .
NextBio616343; -; .
ArrayExpressP19804; -; .
GenevestigatorP19804; -; .
GermOnlineENSRNOG00000002671; Rattus norvegicus; .
GOGO:0030027; C:lamellipodium; ISS:HGNC; .
GOGO:0005624; C:membrane fraction; IDA:RGD; .
GOGO:0048471; C:perinuclear region of cytoplasm; IDA:RGD; .
GOGO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell; .
GOGO:0001726; C:ruffle; ISS:HGNC; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0008144; F:drug binding; IPI:RGD; .
GOGO:0019899; F:enzyme binding; IPI:RGD; .
GOGO:0005504; F:fatty acid binding; IPI:RGD; .
GOGO:0019215; F:intermediate filament binding; IPI:RGD; .
GOGO:0046872; F:metal ion binding; IEA:UniProtKB-KW; .
GOGO:0004550; F:nucleoside diphosphate kinase activity; IDA:RGD; .
GOGO:0004673; F:protein histidine kinase activity; IEA:EC; .
GOGO:0004674; F:protein serine/threonine kinase activity; IDA:RGD; .
GOGO:0071398; P:cellular response to fatty acid; IEP:RGD; .
GOGO:0071333; P:cellular response to glucose stimulus; IEP:RGD; .
GOGO:0034599; P:cellular response to oxidative stress; IEP:RGD; .
GOGO:0006241; P:CTP biosynthetic process; IDA:RGD; .
GOGO:0006183; P:GTP biosynthetic process; IDA:RGD; .
GOGO:0043066; P:negative regulation of apoptotic process; ISS:HGNC; .
GOGO:0002762; P:negative regulation of myeloid leukocyte differentiation; IDA:RGD; .
GOGO:0030819; P:positive regulation of cAMP biosynthetic process; IMP:RGD; .
GOGO:0050679; P:positive regulation of epithelial cell proliferation; ISS:HGNC; .
GOGO:0045618; P:positive regulation of keratinocyte differentiation; ISS:HGNC; .
GOGO:0010976; P:positive regulation of neuron projection development; IMP:RGD; .
GOGO:0046777; P:protein autophosphorylation; IDA:RGD; .
GOGO:0051259; P:protein oligomerization; IDA:RGD; .
GOGO:0060416; P:response to growth hormone stimulus; IEP:RGD; .
GOGO:0006228; P:UTP biosynthetic process; IDA:RGD; .
InterProIPR001564; Nucleoside_diP_kinase; .
InterProIPR023005; Nucleoside_diP_kinase_AS; .
Gene3DG3DSA:3.30.70.141; NDK; 1; .
KOK00940; -; .
PANTHERPTHR11349; Nuc_diP_kinase_core; 1; .
PfamPF00334; NDK; 1; .
PRINTSPR01243; NUCDPKINASE; .
SMARTSM00562; NDK; 1; .
SUPFAMSSF54919; NDK; 1; .
PROSITEPS00469; NDP_KINASES; 1; .


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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server