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World-2DPAGE Repository
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Searching in 'World-2DPAGE Repository [0019]' for entry
matching:
P22062
World-2DPAGE Repository
(0019):
P22062
P22062
General information about the entry
View entry in simple text format
Entry name
PIMT_RAT
Primary accession number
P22062
integrated into World-2DPAGE Repository (0019) on
December 9, 2009 (release 1)
2D Annotations were last modified on
May 30, 2011 (version 2)
General Annotations were last modified on
January 13, 2012 (version 2)
Name and origin of the protein
Description
RecName: Full=Protein-L-isoaspartate(D-aspartate) O-methyltransferase; Short=PIMT; EC=2.1.1.77; AltName: Full=L-isoaspartyl protein carboxyl methyltransferase; AltName: Full=Protein L-isoaspartyl/D-aspartyl methyltransferase; AltName: Full=Protein-beta-aspartate methyltransferase;.
Gene name
Name=Pcmt1
Annotated species
Rattus norvegicus (Rat) [TaxID:
10116
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]
2D-PAGE GEL CHARACTERIZATION
DOI=
10.1111/j.1471-4159.2010.06719.x
;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein
HIPP_SYNAP
{Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
map experimental info
HIPP_SYNAP
MAP LOCATIONS:
SPOT 760
:
pI=7.14; Mw=24682
[identification data]
IDENTIFICATION:
SPOT 760: Peptides number=9. SeqCov=47.1%. MOWSE score=8.22E+4 [
1
].
MAPPING (identification):
SPOT
760
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
].
Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-Prot
P22062; PIMT_RAT.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
2011_12
Entry name
PIMT_RAT
Primary accession number
P22062
Secondary accession number(s)
Q5M7V6
Sequence was last modified on
January 23, 2007 (version 2)
Annotations were last modified on
November 16, 2011 (version 90)
Name and origin of the protein
Description
RecName: Full=Protein-L-isoaspartate(D-aspartate) O-methyltransferase; Short=PIMT; EC=2.1.1.77; AltName: Full=L-isoaspartyl protein carboxyl methyltransferase; AltName: Full=Protein L-isoaspartyl/D-aspartyl methyltransferase; AltName: Full=Protein-beta-aspartate methyltransferase;
Gene name
Name=Pcmt1
Encoded on
Name=Pcmt1
Keywords
Acetylation
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
Methyltransferase
;
Reference proteome
;
S-adenosyl-L-methionine
;
Transferase
.
Copyright
Copyrighted by the UniProt Consortium, see
https://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
M26686; AAA60742.1
; -; mRNA
EMBL
D11475; BAA02034.1
; ALT_INIT; mRNA
EMBL
BC088417; AAH88417.1
; -; mRNA
IPI
IPI00555303; -
; .
PIR
A32449; A32449
; .
RefSeq
NP_037205.2; NM_013073.3
; .
UniGene
Rn.86985; -
; .
ProteinModelPortal
P22062; -
; .
SMR
P22062; 3-226
; .
MINT
MINT-4589251; -
; .
STRING
P22062; -
; .
GeneID
25604; -
; .
KEGG
rno:25604; -
; .
CTD
5110; -
; .
RGD
3268; Pcmt1
; .
eggNOG
roNOG07095; -
; .
GeneTree
ENSGT00510000046974; -
; .
HOVERGEN
HBG004483; -
; .
InParanoid
P22062; -
; .
OrthoDB
EOG4NGGNK; -
; .
NextBio
607327; -
; .
ArrayExpress
P22062; -
; .
Genevestigator
P22062; -
; .
GermOnline
ENSRNOG00000014330; Rattus norvegicus
; .
GO
GO:0005737; C:cytoplasm
; IEA:UniProtKB-SubCell; .
GO
GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity
; IDA:RGD; .
GO
GO:0046498; P:S-adenosylhomocysteine metabolic process
; IDA:RGD; .
GO
GO:0046500; P:S-adenosylmethionine metabolic process
; IDA:RGD; .
InterPro
IPR000682; PCMT
; .
KO
K00573; -
; .
PANTHER
PTHR11579; PCMT
; 1; .
Pfam
PF01135; PCMT
; 1; .
TIGRFAMs
TIGR00080; Pimt
; 1; .
PROSITE
PS01279; PCMT
; 1; .
World-2DPAGE Repository (search AC)
Database constructed and maintained by
SIB
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server