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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0022]' for entry matching: P24090 World-2DPAGE Repository (0022):  P24090 P24090 General information about the entry View entry in simple text format Entry name FETUA_RAT Primary accession number P24090 integrated into World-2DPAGE Repository (0022) on  May 7, 2010 (release 1) 2D Annotations were last modified on June 22, 2011 (version 2) General Annotations were last modified on  November 24, 2011 (version 2) Name and origin of the protein Description RecName: Full=Alpha-2-HS-glycoprotein; AltName: Full=59 kDa bone sialic acid-containing protein; Short=BSP; AltName: Full=Fetuin-A; AltName: Full=Glycoprotein PP63; Flags: Precursor;. Gene name Name=Ahsg Synonyms=Fetua Annotated species Rattus [TaxID: 10114] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000593; Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L. ''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity'' Proteomics 11(16):3369-3379 (2011) 2D PAGE maps for identified proteins How to interpret a protein HCR_LCR_HEART {HCR LCR Cardiac Map} Rattus Tissue: Heart   map experimental info   HCR_LCR_HEART MAP LOCATIONS: SPOT 217: pI=6.05; Mw=38757   [identification data] SPOT 444: pI=6.05; Mw=38757   [identification data] SPOT 621: pI=6.05; Mw=38757   [identification data] IDENTIFICATION: SPOT 217: SeqCov=34.4%. Peptides MS=10/20. Mascot PMF Score=99 [1] SPOT 444: SeqCov=12.8%. Peptides MS=5/20. Mascot PMF Score=32 [1]; SPOT 621: SeqCov=29.8%. Peptides MS=10/20. Mascot PMF Score=96 [1]. PEPTIDE EVIDENCE: SPOT 217: 149-CPILIR-154 (43) / 51-HLLQGFR-57 (45) / 327-VGQPGDAGAAGPVAPLCPGR-346 (105) [1] SPOT 444: 232-ATLIHR-237 (6) / 182-LVEISR-187 (3) / 51-HLLQGFR-57 (51) [1]; SPOT 621: 149-CPILIR-154 (29) / 51-HLLQGFR-57 (50) [1]. MAPPING (identification): SPOT 217: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 444: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 621: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Jatin Burniston, Liverpool John Moores University, UK Cross-references UniProtKB/Swiss-Prot P24090; FETUA_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name FETUA_RAT Primary accession number P24090 Secondary accession number(s) Q5BKD2 Sequence was last modified on  April 1, 1993 (version 2) Annotations were last modified on  November 16, 2011 (version 98) Name and origin of the protein Description RecName: Full=Alpha-2-HS-glycoprotein; AltName: Full=59 kDa bone sialic acid-containing protein; Short=BSP; AltName: Full=Fetuin-A; AltName: Full=Glycoprotein PP63; Flags: Precursor; Gene name Name=Ahsg Synonyms=Fetua Encoded on Name=Ahsg; Synonyms=Fetua Keywords Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Phosphoprotein; Reference proteome; Repeat; Secreted; Signal. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X63446; CAA45042.1; -; mRNA EMBL M29758; AAA75502.1; -; mRNA EMBL D10261; BAA01101.1; -; mRNA EMBL BC091118; AAH91118.1; -; mRNA IPI IPI00327469; -; . PIR A32827; A32827; . RefSeq NP_037030.1; NM_012898.4; . UniGene Rn.32083; -; . ProteinModelPortal P24090; -; . IntAct P24090; 1; . STRING P24090; -; . MEROPS I25.020; -; . PhosphoSite P24090; -; . PRIDE P24090; -; . GeneID 25373; -; . KEGG rno:25373; -; . CTD 197; -; . RGD 2075; Ahsg; . eggNOG roNOG04679; -; . GeneTree ENSGT00530000063413; -; . HOVERGEN HBG051607; -; . NextBio 606393; -; . ArrayExpress P24090; -; . Genevestigator P24090; -; . GermOnline ENSRNOG00000038370; Rattus norvegicus; . GO GO:0031012; C:extracellular matrix; IDA:RGD; . GO GO:0005615; C:extracellular space; IDA:RGD; . GO GO:0043234; C:protein complex; IDA:RGD; . GO GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:InterPro; . GO GO:0030294; F:receptor signaling protein tyrosine kinase inhibitor activity; IDA:RGD; . GO GO:0006953; P:acute-phase response; ISS:UniProtKB; . GO GO:0032869; P:cellular response to insulin stimulus; IEP:RGD; . GO GO:0021987; P:cerebral cortex development; IEP:RGD; . GO GO:0008584; P:male gonad development; IMP:RGD; . GO GO:0030502; P:negative regulation of bone mineralization; ISS:UniProtKB; . GO GO:0030308; P:negative regulation of cell growth; IDA:RGD; . GO GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:RGD; . GO GO:0031100; P:organ regeneration; IEP:RGD; . GO GO:0045780; P:positive regulation of bone resorption; IMP:RGD; . GO GO:0050766; P:positive regulation of phagocytosis; ISS:UniProtKB; . GO GO:0050727; P:regulation of inflammatory response; ISS:UniProtKB; . InterPro IPR000010; Prot_inh_cystat; . InterPro IPR001363; Prot_inh_fetuin_CS; . Pfam PF00031; Cystatin; 1; . SMART SM00043; CY; 2; . PROSITE PS51529; CYSTATIN_FETUIN_A; 2; . PROSITE PS01254; FETUIN_1; 1; . PROSITE PS01255; FETUIN_2; 1; . World-2DPAGE Repository (search AC)