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Searching in 'World-2DPAGE Repository [0022]' for entry matching: P24090




World-2DPAGE Repository (0022):  P24090

P24090


General information about the entry
View entry in simple text format
Entry nameFETUA_RAT
Primary accession numberP24090
integrated into World-2DPAGE Repository (0022) on May 7, 2010 (release 1)
2D Annotations were last modified onJune 22, 2011 (version 2)
General Annotations were last modified on November 24, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Alpha-2-HS-glycoprotein; AltName: Full=59 kDa bone sialic acid-containing protein; Short=BSP; AltName: Full=Fetuin-A; AltName: Full=Glycoprotein PP63; Flags: Precursor;.
Gene nameName=Ahsg
Synonyms=Fetua
Annotated speciesRattus [TaxID: 10114]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/pmic.201000593;
Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L.
''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity''
Proteomics 11(16):3369-3379 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

HCR_LCR_HEART {HCR LCR Cardiac Map}
Rattus
Tissue: Heart
HCR_LCR_HEART
  map experimental info 		 
HCR_LCR_HEART

MAP LOCATIONS:
pI=6.05; Mw=38757  [identification data]
pI=6.05; Mw=38757  [identification data]
pI=6.05; Mw=38757  [identification data]

IDENTIFICATION: SPOT 217: SeqCov=34.4%. Peptides MS=10/20. Mascot PMF Score=99 [1]
SPOT 444: SeqCov=12.8%. Peptides MS=5/20. Mascot PMF Score=32 [1]; SPOT 621: SeqCov=29.8%. Peptides MS=10/20. Mascot PMF Score=96 [1].
PEPTIDE EVIDENCE: SPOT 217: 149-CPILIR-154 (43) / 51-HLLQGFR-57 (45) / 327-VGQPGDAGAAGPVAPLCPGR-346 (105) [1]
SPOT 444: 232-ATLIHR-237 (6) / 182-LVEISR-187 (3) / 51-HLLQGFR-57 (51) [1]; SPOT 621: 149-CPILIR-154 (29) / 51-HLLQGFR-57 (50) [1].
MAPPING (identification):
SPOT 217: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 444: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 621: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Jatin Burniston, Liverpool John Moores University, UK
Cross-references
UniProtKB/Swiss-ProtP24090; FETUA_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameFETUA_RAT
Primary accession numberP24090
Secondary accession number(s) Q5BKD2
Sequence was last modified on April 1, 1993 (version 2)
Annotations were last modified on November 16, 2011 (version 98)
Name and origin of the protein
DescriptionRecName: Full=Alpha-2-HS-glycoprotein; AltName: Full=59 kDa bone sialic acid-containing protein; Short=BSP; AltName: Full=Fetuin-A; AltName: Full=Glycoprotein PP63; Flags: Precursor;
Gene nameName=Ahsg
Synonyms=Fetua
Encoded onName=Ahsg; Synonyms=Fetua
KeywordsComplete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Phosphoprotein; Reference proteome; Repeat; Secreted; Signal.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX63446; CAA45042.1; -; mRNA
EMBLM29758; AAA75502.1; -; mRNA
EMBLD10261; BAA01101.1; -; mRNA
EMBLBC091118; AAH91118.1; -; mRNA
IPIIPI00327469; -; .
PIRA32827; A32827; .
RefSeqNP_037030.1; NM_012898.4; .
UniGeneRn.32083; -; .
ProteinModelPortalP24090; -; .
IntActP24090; 1; .
STRINGP24090; -; .
MEROPSI25.020; -; .
PhosphoSiteP24090; -; .
PRIDEP24090; -; .
GeneID25373; -; .
KEGGrno:25373; -; .
CTD197; -; .
RGD2075; Ahsg; .
eggNOGroNOG04679; -; .
GeneTreeENSGT00530000063413; -; .
HOVERGENHBG051607; -; .
NextBio606393; -; .
ArrayExpressP24090; -; .
GenevestigatorP24090; -; .
GermOnlineENSRNOG00000038370; Rattus norvegicus; .
GOGO:0031012; C:extracellular matrix; IDA:RGD; .
GOGO:0005615; C:extracellular space; IDA:RGD; .
GOGO:0043234; C:protein complex; IDA:RGD; .
GOGO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:InterPro; .
GOGO:0030294; F:receptor signaling protein tyrosine kinase inhibitor activity; IDA:RGD; .
GOGO:0006953; P:acute-phase response; ISS:UniProtKB; .
GOGO:0032869; P:cellular response to insulin stimulus; IEP:RGD; .
GOGO:0021987; P:cerebral cortex development; IEP:RGD; .
GOGO:0008584; P:male gonad development; IMP:RGD; .
GOGO:0030502; P:negative regulation of bone mineralization; ISS:UniProtKB; .
GOGO:0030308; P:negative regulation of cell growth; IDA:RGD; .
GOGO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:RGD; .
GOGO:0031100; P:organ regeneration; IEP:RGD; .
GOGO:0045780; P:positive regulation of bone resorption; IMP:RGD; .
GOGO:0050766; P:positive regulation of phagocytosis; ISS:UniProtKB; .
GOGO:0050727; P:regulation of inflammatory response; ISS:UniProtKB; .
InterProIPR000010; Prot_inh_cystat; .
InterProIPR001363; Prot_inh_fetuin_CS; .
PfamPF00031; Cystatin; 1; .
SMARTSM00043; CY; 2; .
PROSITEPS51529; CYSTATIN_FETUIN_A; 2; .
PROSITEPS01254; FETUIN_1; 1; .
PROSITEPS01255; FETUIN_2; 1; .


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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server