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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0027]' for entry matching: P26040 World-2DPAGE Repository (0027):  P26040 P26040 General information about the entry View entry in simple text format Entry name EZRI_MOUSE Primary accession number P26040 integrated into World-2DPAGE Repository (0027) on  September 30, 2010 (release 1) 2D Annotations were last modified on June 21, 2011 (version 2) General Annotations were last modified on  November 23, 2011 (version 2) Name and origin of the protein Description RecName: Full=Ezrin; AltName: Full=Cytovillin; AltName: Full=Villin-2; AltName: Full=p81;. Gene name Name=Ezr Synonyms=Vil2 Annotated species Mus musculus (Mouse) [TaxID: 10090] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/prca.201000103; Blutke A., Block C., Berendt F., Herbach N., Kemter E., Amann K., Frolich T., Arnold G.J., Wanke R. ''Differential glomerular proteome analysis of two murine nephropathy models at onset of albuminuria'' Proteomics - Clinical Applications 5(6):375-381 (2011) 2D PAGE maps for identified proteins How to interpret a protein GH_4-7 {glomerular protein lysates of a GH-tg animal} Mus musculus (Mouse)   map experimental info   GH_4-7 MAP LOCATIONS: SPOT 4: pI=6.10; Mw=76000   [identification data] SPOT 5: pI=6.20; Mw=76000   [identification data] EXPRESSION: SPOT 4: Avg ratio GH-tg vs. control=-1.59 (p-value=0.0093) [1]; SPOT 5: Avg ratio GH-tg vs. control=-1.59 (p-value=0.0031) [1]. IDENTIFICATION: SPOT 4: SeqCov=39%. Mascot protein score=408 [1] SPOT 5: SeqCov=57%. Mascot protein score=716 [1]. MAPPING (identification): SPOT 4: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 5: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Andreas Blutke, Institute of Veterinary Pathology, University Munich, Germany Cross-references REPRODUCTION-2DPAGE P26040; P26040. UniProtKB/Swiss-Prot P26040; EZRI_MOUSE. World-2DPAGE Repository P26040; EZRI_MOUSE. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name EZRI_MOUSE Primary accession number P26040 Secondary accession number(s) Q80ZT8 Q9DCI1 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  November 16, 2011 (version 110) Name and origin of the protein Description RecName: Full=Ezrin; AltName: Full=Cytovillin; AltName: Full=Villin-2; AltName: Full=p81; Gene name Name=Ezr Synonyms=Vil2 Encoded on Name=Ezr; Synonyms=Vil2 Keywords Acetylation; Cell membrane; Cell projection; Cell shape; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Membrane; Phosphoprotein; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X60671; CAA43086.1; -; mRNA EMBL AK002766; BAB22341.1; -; mRNA EMBL BC048181; AAH48181.2; -; mRNA IPI IPI00330862; -; . PIR B41129; B41129; . RefSeq NP_033536.2; NM_009510.2; . UniGene Mm.277812; -; . ProteinModelPortal P26040; -; . SMR P26040; 1-586; . IntAct P26040; 3; . MINT MINT-1708640; -; . STRING P26040; -; . TCDB 8.A.25.1.1; ezrin/radixin/moesin (Ezrin) family; . PhosphoSite P26040; -; . REPRODUCTION-2DPAGE P26040; -; . PRIDE P26040; -; . Ensembl ENSMUST00000064234; ENSMUSP00000063734; ENSMUSG00000052397; . GeneID 22350; -; . KEGG mmu:22350; -; . CTD 7430; -; . MGI MGI:98931; Ezr; . eggNOG roNOG13879; -; . HOGENOM HBG446392; -; . HOVERGEN HBG002185; -; . InParanoid P26040; -; . OMA SEGIRDD; -; . OrthoDB EOG4C5CJJ; -; . PhylomeDB P26040; -; . NextBio 457682; -; . ArrayExpress P26040; -; . Bgee P26040; -; . CleanEx MM_EZR; -; . Genevestigator P26040; -; . GermOnline ENSMUSG00000052397; Mus musculus; . GO GO:0005884; C:actin filament; ISS:UniProtKB; . GO GO:0016324; C:apical plasma membrane; IDA:MGI; . GO GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell; . GO GO:0019898; C:extrinsic to membrane; ISS:UniProtKB; . GO GO:0005932; C:microtubule basal body; IDA:MGI; . GO GO:0031528; C:microvillus membrane; IEA:UniProtKB-SubCell; . GO GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell; . GO GO:0001931; C:uropod; IDA:MGI; . GO GO:0051015; F:actin filament binding; ISS:UniProtKB; . GO GO:0050839; F:cell adhesion molecule binding; ISS:BHF-UCL; . GO GO:0051017; P:actin filament bundle assembly; ISS:UniProtKB; . GO GO:0035088; P:establishment or maintenance of apical/basal cell polarity; IMP:MGI; . GO GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW; . InterPro IPR019749; Band_41_domain; . InterPro IPR019750; Band_41_fam; . InterPro IPR011174; ERM; . InterPro IPR011259; ERM_C; . InterPro IPR000798; Ez/rad/moesin; . InterPro IPR014352; FERM/acyl-CoA-bd_prot_3-hlx; . InterPro IPR019748; FERM_central; . InterPro IPR019747; FERM_CS; . InterPro IPR000299; FERM_domain; . InterPro IPR018979; FERM_N; . InterPro IPR018980; FERM_PH-like_C; . InterPro IPR008954; Moesin; . InterPro IPR011993; PH_type; . Gene3D G3DSA:1.20.80.10; ACBP; 1; . Gene3D G3DSA:2.30.29.30; PH_type; 1; . KO K08007; -; . Pfam PF00769; ERM; 1; . Pfam PF09380; FERM_C; 1; . Pfam PF00373; FERM_M; 1; . Pfam PF09379; FERM_N; 1; . PIRSF PIRSF002305; ERM; 1; . PRINTS PR00935; BAND41; . PRINTS PR00661; ERMFAMILY; . SMART SM00295; B41; 1; . SUPFAM SSF47031; FERM_3-hlx; 1; . SUPFAM SSF48678; Moesin; 1; . PROSITE PS00660; FERM_1; 1; . PROSITE PS00661; FERM_2; 1; . PROSITE PS50057; FERM_3; 1; . World-2DPAGE Repository (search AC)