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Searching in 'World-2DPAGE Repository [0004]' for entry matching: P27139

World-2DPAGE Repository (0004):  P27139


General information about the entry
View entry in simple text format
Entry nameCAH2_RAT
Primary accession numberP27139
integrated into World-2DPAGE Repository (0004) on October 13, 2008 (release 1)
2D Annotations were last modified onMay 18, 2011 (version 2)
General Annotations were last modified on December 22, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Carbonic anhydrase 2; EC=; AltName: Full=Carbonate dehydratase II; AltName: Full=Carbonic anhydrase II; Short=CA-II;.
Gene nameName=Ca2
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
PubMed=19343716; DOI=10.1002/pmic.200800664; [NCBI, EBI, Israel, Japan]
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of the mature rat olfactory bulb''
Proteomics 9(1):2593-2599 (2009)
2D PAGE maps for identified proteins
How to interpret a protein

OB21DSUB {2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb
  map experimental info

pI=7.01; Mw=28000  [identification data]

MAPPING (identification):
SPOT 611: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
UniProtKB/Swiss-ProtP27139; CAH2_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameCAH2_RAT
Primary accession numberP27139
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on November 16, 2011 (version 97)
Name and origin of the protein
DescriptionRecName: Full=Carbonic anhydrase 2; EC=; AltName: Full=Carbonate dehydratase II; AltName: Full=Carbonic anhydrase II; Short=CA-II;
Gene nameName=Ca2
Encoded onName=Ca2
KeywordsAcetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Lyase; Metal-binding; Phosphoprotein; Reference proteome; Zinc.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLX58294; CAA41227.1; -; mRNA
EMBLU60578; AAC53104.1; -; Genomic_DNA
EMBLU60572; AAC53104.1; JOINED; Genomic_DNA
EMBLU60573; AAC53104.1; JOINED; Genomic_DNA
EMBLU60574; AAC53104.1; JOINED; Genomic_DNA
EMBLU60575; AAC53104.1; JOINED; Genomic_DNA
EMBLU60576; AAC53104.1; JOINED; Genomic_DNA
EMBLU60577; AAC53104.1; JOINED; Genomic_DNA
EMBLBC065577; AAH65577.1; -; mRNA
IPIIPI00230787; -; .
PIRJH0527; JH0527; .
RefSeqNP_062164.1; NM_019291.1; .
UniGeneRn.26083; -; .
ProteinModelPortalP27139; -; .
SMRP27139; 2-260; .
IntActP27139; 1; .
STRINGP27139; -; .
PhosphoSiteP27139; -; .
World-2DPAGE0004:P27139; -; .
PRIDEP27139; -; .
EnsemblENSRNOT00000013354; ENSRNOP00000013354; ENSRNOG00000009629; .
GeneID54231; -; .
KEGGrno:54231; -; .
UCSCNM_019291; rat; .
CTD12349; -; .
RGD2240; Ca2; .
eggNOGroNOG15031; -; .
GeneTreeENSGT00560000076828; -; .
HOVERGENHBG002837; -; .
InParanoidP27139; -; .
OrthoDBEOG4X97HR; -; .
PhylomeDBP27139; -; .
NextBio610662; -; .
ArrayExpressP27139; -; .
GenevestigatorP27139; -; .
GermOnlineENSRNOG00000009629; Rattus norvegicus; .
GOGO:0045177; C:apical part of cell; IDA:RGD; .
GOGO:0030424; C:axon; IDA:RGD; .
GOGO:0016323; C:basolateral plasma membrane; IDA:RGD; .
GOGO:0005615; C:extracellular space; IDA:RGD; .
GOGO:0005902; C:microvillus; IDA:RGD; .
GOGO:0004089; F:carbonate dehydratase activity; IDA:RGD; .
GOGO:0005515; F:protein binding; IPI:RGD; .
GOGO:0001822; P:kidney development; IEP:RGD; .
GOGO:0042475; P:odontogenesis of dentin-containing tooth; IEP:RGD; .
GOGO:0006730; P:one-carbon metabolic process; IEA:InterPro; .
GOGO:0030316; P:osteoclast differentiation; TAS:RGD; .
GOGO:0045780; P:positive regulation of bone resorption; IMP:RGD; .
GOGO:0032849; P:positive regulation of cellular pH reduction; IMP:RGD; .
GOGO:0045672; P:positive regulation of osteoclast differentiation; IMP:RGD; .
GOGO:0030641; P:regulation of cellular pH; TAS:RGD; .
GOGO:0043627; P:response to estrogen stimulus; IEP:RGD; .
GOGO:0009268; P:response to pH; IEP:RGD; .
GOGO:0006950; P:response to stress; IEP:RGD; .
GOGO:0010043; P:response to zinc ion; IEP:RGD; .
InterProIPR023561; Carbonic_anhydrase_a-class; .
InterProIPR001148; Carbonic_anhydrase_a-class_cat; .
InterProIPR018338; Carbonic_anhydrase_a-class_CS; .
InterProIPR018440; Carbonic_anhydrase_CA2; .
Gene3DG3DSA:; Euk_COanhd; 1; .
KOK01672; -; .
PANTHERPTHR18952:SF28; Carbonic_anhydrase_CA2; 1; .
PANTHERPTHR18952; Euk_COanhd; 1; .
PfamPF00194; Carb_anhydrase; 1; .
SUPFAMSSF51069; Euk_COanhd; 1; .
PROSITEPS00162; ALPHA_CA_1; 1; .
PROSITEPS51144; ALPHA_CA_2; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server