World-2DPAGE Repository

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.

References

[1]	MAPPING ON GEL PubMed=19343716; DOI=10.1002/pmic.200800664; [NCBI, EBI, Israel, Japan] Maurya D.K., Sundaram C.S., Bhargava P. ''Proteome profile of the mature rat olfactory bulb'' Proteomics 9(1):2593-2599 (2009)

2D PAGE maps for identified proteins

How to interpret a protein

OB21DSUB {2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb

map experimental info

OB21DSUB

MAP LOCATIONS:

SPOT 608:

pI=5.89; Mw=29000

[identification data]

MAPPING (identification):

SPOT 608: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India

Cross-references

UniProtKB/Swiss-Prot

P27605; HPRT_RAT.

2D PAGE maps for identified proteins
How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry name	HPRT_RAT
Primary accession number	P27605
Secondary accession number(s)	P70469 Q4KMC5 Q62926
Sequence was last modified on	August 1, 1992 (version 1)
Annotations were last modified on	November 16, 2011 (version 93)
Name and origin of the protein
Description	RecName: Full=Hypoxanthine-guanine phosphoribosyltransferase; Short=HGPRT; Short=HGPRTase; EC=2.4.2.8;
Gene name	Name=Hprt1 Synonyms=Hprt
Encoded on	Name=Hprt1; Synonyms=Hprt
Keywords	Complete proteome; Cytoplasm; Direct protein sequencing; Glycosyltransferase; Magnesium; Metal-binding; Nucleotide-binding; Purine salvage; Reference proteome; Transferase.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL	M63983; AAA41350.1; -; mRNA
EMBL	S79292; AAB21288.1; -; mRNA
EMBL	X62085; CAA43997.1; -; mRNA
EMBL	AF001282; AAB65640.1; -; Genomic_DNA
EMBL	AF001278; AAB65640.1; JOINED; Genomic_DNA
EMBL	AF009655; AAB65640.1; JOINED; Genomic_DNA
EMBL	AF009656; AAB65640.1; JOINED; Genomic_DNA
EMBL	AF001279; AAB65640.1; JOINED; Genomic_DNA
EMBL	AF001280; AAB65640.1; JOINED; Genomic_DNA
EMBL	AF001281; AAB65640.1; JOINED; Genomic_DNA
EMBL	BC098629; AAH98629.1; -; mRNA
EMBL	U06049; AAA56887.1; -; Genomic_DNA
IPI	IPI00560533; -; .
PIR	S18140; S18140; .
RefSeq	NP_036715.1; NM_012583.2; .
UniGene	Rn.47; -; .
ProteinModelPortal	P27605; -; .
SMR	P27605; 5-218; .
IntAct	P27605; 2; .
STRING	P27605; -; .
PhosphoSite	P27605; -; .
World-2DPAGE	0004:P27605; -; .
PRIDE	P27605; -; .
Ensembl	ENSRNOT00000045153; ENSRNOP00000043388; ENSRNOG00000031367; .
GeneID	24465; -; .
KEGG	rno:24465; -; .
UCSC	NM_012583; rat; .
CTD	3251; -; .
RGD	2826; Hprt1; .
eggNOG	roNOG08855; -; .
HOVERGEN	HBG000242; -; .
InParanoid	P27605; -; .
OrthoDB	EOG4H72CM; -; .
PhylomeDB	P27605; -; .
NextBio	603395; -; .
ArrayExpress	P27605; -; .
Genevestigator	P27605; -; .
GermOnline	ENSRNOG00000031367; Rattus norvegicus; .
GO	GO:0005829; C:cytosol; IBA:RefGenome; .
GO	GO:0005625; C:soluble fraction; IDA:RGD; .
GO	GO:0052657; F:guanine phosphoribosyltransferase activity; ISS:UniProtKB; .
GO	GO:0004422; F:hypoxanthine phosphoribosyltransferase activity; IDA:RGD; .
GO	GO:0000287; F:magnesium ion binding; IBA:RefGenome; .
GO	GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW; .
GO	GO:0006168; P:adenine salvage; IBA:RefGenome; .
GO	GO:0032869; P:cellular response to insulin stimulus; IEP:RGD; .
GO	GO:0021954; P:central nervous system neuron development; IBA:RefGenome; .
GO	GO:0021895; P:cerebral cortex neuron differentiation; IBA:RefGenome; .
GO	GO:0019835; P:cytolysis; IBA:RefGenome; .
GO	GO:0048813; P:dendrite morphogenesis; IBA:RefGenome; .
GO	GO:0046038; P:GMP catabolic process; ISS:UniProtKB; .
GO	GO:0032263; P:GMP salvage; IBA:RefGenome; .
GO	GO:0007625; P:grooming behavior; IBA:RefGenome; .
GO	GO:0006178; P:guanine salvage; ISS:UniProtKB; .
GO	GO:0043103; P:hypoxanthine salvage; ISS:UniProtKB; .
GO	GO:0032264; P:IMP salvage; IBA:RefGenome; .
GO	GO:0046651; P:lymphocyte proliferation; IBA:RefGenome; .
GO	GO:0045964; P:positive regulation of dopamine metabolic process; IBA:RefGenome; .
GO	GO:0006166; P:purine ribonucleoside salvage; IBA:RefGenome; .
GO	GO:0001975; P:response to amphetamine; IBA:RefGenome; .
GO	GO:0007283; P:spermatogenesis; IEP:RGD; .
GO	GO:0021756; P:striatum development; IBA:RefGenome; .
InterPro	IPR005904; Hxn_phspho_trans; .
InterPro	IPR000836; PRibTrfase; .
KO	K00760; -; .
Pfam	PF00156; Pribosyltran; 1; .
TIGRFAMs	TIGR01203; HGPRTase; 1; .
PROSITE	PS00103; PUR_PYR_PR_TRANSFER; 1; .

World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server

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