World-2DPAGE Repository
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World-2DPAGE Repository
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Select Remote Interfaces
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SWISS-2DPAGE
World-2DPAGE Portal
Exclude local DBs
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Searching in 'World-2DPAGE Repository [0004]' for entry
matching:
P27605
World-2DPAGE Repository
(0004):
P27605
P27605
General information about the entry
View entry in simple text format
Entry name
HPRT_RAT
Primary accession number
P27605
integrated into World-2DPAGE Repository (0004) on
October 13, 2008 (release 1)
2D Annotations were last modified on
May 18, 2011 (version 2)
General Annotations were last modified on
December 22, 2011 (version 2)
Name and origin of the protein
Description
RecName: Full=Hypoxanthine-guanine phosphoribosyltransferase; Short=HGPRT; Short=HGPRTase; EC=2.4.2.8;.
Gene name
Name=Hprt1
Synonyms=Hprt
Annotated species
Rattus norvegicus (Rat) [TaxID:
10116
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]
MAPPING ON GEL
PubMed=19343716; DOI=
10.1002/pmic.200800664
; [
NCBI
,
EBI
,
Israel
,
Japan
]
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of the mature rat olfactory bulb''
Proteomics 9(1):2593-2599 (2009)
2D PAGE maps for identified proteins
How to interpret a protein
OB21DSUB
{2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb
map experimental info
OB21DSUB
MAP LOCATIONS:
SPOT 608
:
pI=5.89; Mw=29000
[identification data]
MAPPING (identification):
SPOT
608
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
].
Copyright
Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
Cross-references
UniProtKB/Swiss-Prot
P27605; HPRT_RAT.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
2011_12
Entry name
HPRT_RAT
Primary accession number
P27605
Secondary accession number(s)
P70469 Q4KMC5 Q62926
Sequence was last modified on
August 1, 1992 (version 1)
Annotations were last modified on
November 16, 2011 (version 93)
Name and origin of the protein
Description
RecName: Full=Hypoxanthine-guanine phosphoribosyltransferase; Short=HGPRT; Short=HGPRTase; EC=2.4.2.8;
Gene name
Name=Hprt1
Synonyms=Hprt
Encoded on
Name=Hprt1; Synonyms=Hprt
Keywords
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
Glycosyltransferase
;
Magnesium
;
Metal-binding
;
Nucleotide-binding
;
Purine salvage
;
Reference proteome
;
Transferase
.
Copyright
Copyrighted by the UniProt Consortium, see
https://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
M63983; AAA41350.1
; -; mRNA
EMBL
S79292; AAB21288.1
; -; mRNA
EMBL
X62085; CAA43997.1
; -; mRNA
EMBL
AF001282; AAB65640.1
; -; Genomic_DNA
EMBL
AF001278; AAB65640.1
; JOINED; Genomic_DNA
EMBL
AF009655; AAB65640.1
; JOINED; Genomic_DNA
EMBL
AF009656; AAB65640.1
; JOINED; Genomic_DNA
EMBL
AF001279; AAB65640.1
; JOINED; Genomic_DNA
EMBL
AF001280; AAB65640.1
; JOINED; Genomic_DNA
EMBL
AF001281; AAB65640.1
; JOINED; Genomic_DNA
EMBL
BC098629; AAH98629.1
; -; mRNA
EMBL
U06049; AAA56887.1
; -; Genomic_DNA
IPI
IPI00560533; -
; .
PIR
S18140; S18140
; .
RefSeq
NP_036715.1; NM_012583.2
; .
UniGene
Rn.47; -
; .
ProteinModelPortal
P27605; -
; .
SMR
P27605; 5-218
; .
IntAct
P27605; 2
; .
STRING
P27605; -
; .
PhosphoSite
P27605; -
; .
World-2DPAGE
0004:P27605; -
; .
PRIDE
P27605; -
; .
Ensembl
ENSRNOT00000045153; ENSRNOP00000043388
; ENSRNOG00000031367; .
GeneID
24465; -
; .
KEGG
rno:24465; -
; .
UCSC
NM_012583; rat
; .
CTD
3251; -
; .
RGD
2826; Hprt1
; .
eggNOG
roNOG08855; -
; .
HOVERGEN
HBG000242; -
; .
InParanoid
P27605; -
; .
OrthoDB
EOG4H72CM; -
; .
PhylomeDB
P27605; -
; .
NextBio
603395; -
; .
ArrayExpress
P27605; -
; .
Genevestigator
P27605; -
; .
GermOnline
ENSRNOG00000031367; Rattus norvegicus
; .
GO
GO:0005829; C:cytosol
; IBA:RefGenome; .
GO
GO:0005625; C:soluble fraction
; IDA:RGD; .
GO
GO:0052657; F:guanine phosphoribosyltransferase activity
; ISS:UniProtKB; .
GO
GO:0004422; F:hypoxanthine phosphoribosyltransferase activity
; IDA:RGD; .
GO
GO:0000287; F:magnesium ion binding
; IBA:RefGenome; .
GO
GO:0000166; F:nucleotide binding
; IEA:UniProtKB-KW; .
GO
GO:0006168; P:adenine salvage
; IBA:RefGenome; .
GO
GO:0032869; P:cellular response to insulin stimulus
; IEP:RGD; .
GO
GO:0021954; P:central nervous system neuron development
; IBA:RefGenome; .
GO
GO:0021895; P:cerebral cortex neuron differentiation
; IBA:RefGenome; .
GO
GO:0019835; P:cytolysis
; IBA:RefGenome; .
GO
GO:0048813; P:dendrite morphogenesis
; IBA:RefGenome; .
GO
GO:0046038; P:GMP catabolic process
; ISS:UniProtKB; .
GO
GO:0032263; P:GMP salvage
; IBA:RefGenome; .
GO
GO:0007625; P:grooming behavior
; IBA:RefGenome; .
GO
GO:0006178; P:guanine salvage
; ISS:UniProtKB; .
GO
GO:0043103; P:hypoxanthine salvage
; ISS:UniProtKB; .
GO
GO:0032264; P:IMP salvage
; IBA:RefGenome; .
GO
GO:0046651; P:lymphocyte proliferation
; IBA:RefGenome; .
GO
GO:0045964; P:positive regulation of dopamine metabolic process
; IBA:RefGenome; .
GO
GO:0006166; P:purine ribonucleoside salvage
; IBA:RefGenome; .
GO
GO:0001975; P:response to amphetamine
; IBA:RefGenome; .
GO
GO:0007283; P:spermatogenesis
; IEP:RGD; .
GO
GO:0021756; P:striatum development
; IBA:RefGenome; .
InterPro
IPR005904; Hxn_phspho_trans
; .
InterPro
IPR000836; PRibTrfase
; .
KO
K00760; -
; .
Pfam
PF00156; Pribosyltran
; 1; .
TIGRFAMs
TIGR01203; HGPRTase
; 1; .
PROSITE
PS00103; PUR_PYR_PR_TRANSFER
; 1; .
World-2DPAGE Repository (search AC)
Database constructed and maintained by
SIB
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
Expasy web server