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World-2DPAGE Repository
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SWISS-2DPAGE
World-2DPAGE Portal
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Searching in 'World-2DPAGE Repository [0004]' for entry
matching:
P37377
World-2DPAGE Repository
(0004):
P37377
P37377
General information about the entry
View entry in simple text format
Entry name
SYUA_RAT
Primary accession number
P37377
integrated into World-2DPAGE Repository (0004) on
October 13, 2008 (release 1)
2D Annotations were last modified on
May 18, 2011 (version 2)
General Annotations were last modified on
December 22, 2011 (version 2)
Name and origin of the protein
Description
RecName: Full=Alpha-synuclein;.
Gene name
Name=Snca
Annotated species
Rattus norvegicus (Rat) [TaxID:
10116
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]
MAPPING ON GEL
PubMed=19343716; DOI=
10.1002/pmic.200800664
; [
NCBI
,
EBI
,
Israel
,
Japan
]
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of the mature rat olfactory bulb''
Proteomics 9(1):2593-2599 (2009)
2D PAGE maps for identified proteins
How to interpret a protein
OB21DSUB
{2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb
map experimental info
OB21DSUB
MAP LOCATIONS:
SPOT 758
:
pI=4.71; Mw=18000
[identification data]
MAPPING (identification):
SPOT
758
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
].
Copyright
Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
Cross-references
UniProtKB/Swiss-Prot
P37377; SYUA_RAT.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
2011_12
Entry name
SYUA_RAT
Primary accession number
P37377
Secondary accession number(s)
P37378 Q53YM9
Sequence was last modified on
October 1, 1994 (version 1)
Annotations were last modified on
December 14, 2011 (version 93)
Name and origin of the protein
Description
RecName: Full=Alpha-synuclein;
Gene name
Name=Snca
Encoded on
Name=Snca
Keywords
Alternative splicing
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
Phosphoprotein
;
Reference proteome
;
Repeat
;
Ubl conjugation
.
Copyright
Copyrighted by the UniProt Consortium, see
https://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
S73007; AAB20688.1
; -; mRNA
EMBL
S73008; AAB20689.1
; -; mRNA
EMBL
S73009; AAB20690.1
; -; mRNA
EMBL
AF007758; AAC16026.1
; -; mRNA
EMBL
AY550005; AAS55694.1
; -; mRNA
EMBL
AY550006; AAS55695.1
; -; mRNA
EMBL
BC087682; AAH87682.1
; -; mRNA
IPI
IPI00205493; -
; .
IPI
IPI00231846; -
; .
IPI
IPI00388903; -
; .
PIR
B43959; B43959
; .
RefSeq
NP_062042.1; NM_019169.2
; .
UniGene
Rn.1827; -
; .
ProteinModelPortal
P37377; -
; .
SMR
P37377; 1-140
; .
STRING
P37377; -
; .
PhosphoSite
P37377; -
; .
World-2DPAGE
0004:P37377; -
; .
PRIDE
P37377; -
; .
Ensembl
ENSRNOT00000039247; ENSRNOP00000030609
; ENSRNOG00000008656; .
Ensembl
ENSRNOT00000042485; ENSRNOP00000040281
; ENSRNOG00000008656; .
GeneID
29219; -
; .
KEGG
rno:29219; -
; .
UCSC
NM_019169; rat
; .
CTD
6622; -
; .
RGD
3729; Snca
; .
eggNOG
roNOG18011; -
; .
HOVERGEN
HBG000481; -
; .
OMA
PENEAYE; -
; .
OrthoDB
EOG4FFD3B; -
; .
NextBio
608409; -
; .
ArrayExpress
P37377; -
; .
Genevestigator
P37377; -
; .
GermOnline
ENSRNOG00000008656; Rattus norvegicus
; .
GO
GO:0030659; C:cytoplasmic vesicle membrane
; IDA:BHF-UCL; .
GO
GO:0005829; C:cytosol
; IDA:RGD; .
GO
GO:0005792; C:microsome
; IDA:RGD; .
GO
GO:0005739; C:mitochondrion
; IDA:BHF-UCL; .
GO
GO:0005625; C:soluble fraction
; IDA:RGD; .
GO
GO:0008021; C:synaptic vesicle
; IDA:RGD; .
GO
GO:0043195; C:terminal button
; IDA:RGD; .
GO
GO:0008017; F:microtubule binding
; IDA:UniProtKB; .
GO
GO:0043274; F:phospholipase binding
; IPI:RGD; .
GO
GO:0005543; F:phospholipid binding
; IDA:RGD; .
GO
GO:0019904; F:protein domain specific binding
; IPI:RGD; .
GO
GO:0047485; F:protein N-terminus binding
; IDA:RGD; .
GO
GO:0048148; P:behavioral response to cocaine
; IMP:RGD; .
GO
GO:0045963; P:negative regulation of dopamine metabolic process
; IMP:BHF-UCL; .
GO
GO:0043524; P:negative regulation of neuron apoptosis
; IMP:RGD; .
GO
GO:0001933; P:negative regulation of protein phosphorylation
; IMP:BHF-UCL; .
GO
GO:0014059; P:regulation of dopamine secretion
; IEA:InterPro; .
InterPro
IPR001058; Synuclein
; .
InterPro
IPR002460; Synuclein_alpha
; .
Gene3D
G3DSA:1.10.287.700; Synuclein
; 1; .
KO
K04528; -
; .
PANTHER
PTHR13820; Synuclein
; 1; .
Pfam
PF01387; Synuclein
; 1; .
PRINTS
PR01212; ASYNUCLEIN
; .
PRINTS
PR01211; SYNUCLEIN
; .
World-2DPAGE Repository (search AC)
Database constructed and maintained by
SIB
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
Expasy web server