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Searching in 'World-2DPAGE Repository [0014]' for entry matching: P45592




World-2DPAGE Repository (0014):  P45592

P45592


General information about the entry
View entry in simple text format
Entry nameCOF1_RAT
Primary accession numberP45592
integrated into World-2DPAGE Repository (0014) on October 13, 2008 (release 1)
2D Annotations were last modified onJune 1, 2011 (version 3)
General Annotations were last modified on November 25, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Cofilin-1; AltName: Full=Cofilin, non-muscle isoform;.
Gene nameName=Cfl1
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/pmic.200900680;
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of whole cerebellum of the mature rat''
Proteomics 10(23):4311-4319 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_CEREBELLUM_21D {Proteome of 21 days old rat cerebellum}
Rattus norvegicus (Rat)
Tissue: Cerebellum
RAT_CEREBELLUM_21D
  map experimental info 		 
RAT_CEREBELLUM_21D

MAP LOCATIONS:
pI=8.34; Mw=15000  [identification data]

IDENTIFICATION: SPOT 3254: SeqCov=57%. MascotPMF=62 [1].
MAPPING (identification):
SPOT 3254: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
Cross-references
PRIDE10017.
UniProtKB/Swiss-ProtP45592; COF1_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameCOF1_RAT
Primary accession numberP45592
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on November 16, 2011 (version 103)
Name and origin of the protein
DescriptionRecName: Full=Cofilin-1; AltName: Full=Cofilin, non-muscle isoform;
Gene nameName=Cfl1
Encoded onName=Cfl1
KeywordsAcetylation; Actin-binding; Cell membrane; Cell projection; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Membrane; Nucleus; Phosphoprotein; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX62908; CAA44694.1; -; mRNA
EMBLBC059143; AAH59143.1; -; mRNA
EMBLBC086533; AAH86533.1; -; mRNA
IPIIPI00327144; -; .
PIRS49101; S49101; .
RefSeqNP_058843.1; NM_017147.2; .
UniGeneRn.11675; -; .
ProteinModelPortalP45592; -; .
SMRP45592; 1-166; .
IntActP45592; 1; .
MINTMINT-247733; -; .
STRINGP45592; -; .
PhosphoSiteP45592; -; .
World-2DPAGE0004:P45592; -; .
PRIDEP45592; -; .
EnsemblENSRNOT00000015962; ENSRNOP00000059624; ENSRNOG00000020660; .
GeneID29271; -; .
KEGGrno:29271; -; .
UCSCNM_017147; rat; .
CTD1072; -; .
RGD69285; Cfl1; .
eggNOGmaNOG13326; -; .
GeneTreeENSGT00440000033289; -; .
HOVERGENHBG000381; -; .
InParanoidP45592; -; .
OrthoDBEOG4WSWBP; -; .
PhylomeDBP45592; -; .
NextBio608622; -; .
ArrayExpressP45592; -; .
GenevestigatorP45592; -; .
GermOnlineENSRNOG00000020660; Rattus norvegicus; .
GOGO:0005737; C:cytoplasm; IDA:RGD; .
GOGO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell; .
GOGO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell; .
GOGO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell; .
GOGO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell; .
GOGO:0003779; F:actin binding; IMP:RGD; .
GOGO:0030030; P:cell projection organization; IDA:MGI; .
GOGO:0045792; P:negative regulation of cell size; IDA:MGI; .
GOGO:0006606; P:protein import into nucleus; IMP:RGD; .
InterProIPR002108; Actin-bd_cofilin/tropomyosin; .
InterProIPR017904; ADF/Cofilin/Destrin; .
KOK05765; -; .
PfamPF00241; Cofilin_ADF; 1; .
PRINTSPR00006; COFILIN; .
SMARTSM00102; ADF; 1; .
PROSITEPS51263; ADF_H; 1; .


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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server