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World-2DPAGE Repository
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Searching in 'World-2DPAGE Repository [0014]' for entry
matching:
P45592
World-2DPAGE Repository
(0014):
P45592
P45592
General information about the entry
View entry in simple text format
Entry name
COF1_RAT
Primary accession number
P45592
integrated into World-2DPAGE Repository (0014) on
October 13, 2008 (release 1)
2D Annotations were last modified on
June 1, 2011 (version 3)
General Annotations were last modified on
November 25, 2011 (version 2)
Name and origin of the protein
Description
RecName: Full=Cofilin-1; AltName: Full=Cofilin, non-muscle isoform;.
Gene name
Name=Cfl1
Annotated species
Rattus norvegicus (Rat) [TaxID:
10116
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]
2D-PAGE GEL CHARACTERIZATION
DOI=
10.1002/pmic.200900680
;
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of whole cerebellum of the mature rat''
Proteomics 10(23):4311-4319 (2010)
2D PAGE maps for identified proteins
How to interpret a protein
RAT_CEREBELLUM_21D
{Proteome of 21 days old rat cerebellum}
Rattus norvegicus (Rat)
Tissue: Cerebellum
map experimental info
RAT_CEREBELLUM_21D
MAP LOCATIONS:
SPOT 3254
:
pI=8.34; Mw=15000
[identification data]
IDENTIFICATION:
SPOT 3254: SeqCov=57%. MascotPMF=62 [
1
].
MAPPING (identification):
SPOT
3254
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
].
Copyright
Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
Cross-references
PRIDE
10017.
UniProtKB/Swiss-Prot
P45592; COF1_RAT.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
2011_11
Entry name
COF1_RAT
Primary accession number
P45592
Sequence was last modified on
January 23, 2007 (version 3)
Annotations were last modified on
November 16, 2011 (version 103)
Name and origin of the protein
Description
RecName: Full=Cofilin-1; AltName: Full=Cofilin, non-muscle isoform;
Gene name
Name=Cfl1
Encoded on
Name=Cfl1
Keywords
Acetylation
;
Actin-binding
;
Cell membrane
;
Cell projection
;
Complete proteome
;
Cytoplasm
;
Cytoskeleton
;
Direct protein sequencing
;
Membrane
;
Nucleus
;
Phosphoprotein
;
Reference proteome
.
Copyright
Copyrighted by the UniProt Consortium, see
https://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
X62908; CAA44694.1
; -; mRNA
EMBL
BC059143; AAH59143.1
; -; mRNA
EMBL
BC086533; AAH86533.1
; -; mRNA
IPI
IPI00327144; -
; .
PIR
S49101; S49101
; .
RefSeq
NP_058843.1; NM_017147.2
; .
UniGene
Rn.11675; -
; .
ProteinModelPortal
P45592; -
; .
SMR
P45592; 1-166
; .
IntAct
P45592; 1
; .
MINT
MINT-247733; -
; .
STRING
P45592; -
; .
PhosphoSite
P45592; -
; .
World-2DPAGE
0004:P45592; -
; .
PRIDE
P45592; -
; .
Ensembl
ENSRNOT00000015962; ENSRNOP00000059624
; ENSRNOG00000020660; .
GeneID
29271; -
; .
KEGG
rno:29271; -
; .
UCSC
NM_017147; rat
; .
CTD
1072; -
; .
RGD
69285; Cfl1
; .
eggNOG
maNOG13326; -
; .
GeneTree
ENSGT00440000033289; -
; .
HOVERGEN
HBG000381; -
; .
InParanoid
P45592; -
; .
OrthoDB
EOG4WSWBP; -
; .
PhylomeDB
P45592; -
; .
NextBio
608622; -
; .
ArrayExpress
P45592; -
; .
Genevestigator
P45592; -
; .
GermOnline
ENSRNOG00000020660; Rattus norvegicus
; .
GO
GO:0005737; C:cytoplasm
; IDA:RGD; .
GO
GO:0005856; C:cytoskeleton
; IEA:UniProtKB-SubCell; .
GO
GO:0031258; C:lamellipodium membrane
; IEA:UniProtKB-SubCell; .
GO
GO:0016363; C:nuclear matrix
; IEA:UniProtKB-SubCell; .
GO
GO:0032587; C:ruffle membrane
; IEA:UniProtKB-SubCell; .
GO
GO:0003779; F:actin binding
; IMP:RGD; .
GO
GO:0030030; P:cell projection organization
; IDA:MGI; .
GO
GO:0045792; P:negative regulation of cell size
; IDA:MGI; .
GO
GO:0006606; P:protein import into nucleus
; IMP:RGD; .
InterPro
IPR002108; Actin-bd_cofilin/tropomyosin
; .
InterPro
IPR017904; ADF/Cofilin/Destrin
; .
KO
K05765; -
; .
Pfam
PF00241; Cofilin_ADF
; 1; .
PRINTS
PR00006; COFILIN
; .
SMART
SM00102; ADF
; 1; .
PROSITE
PS51263; ADF_H
; 1; .
World-2DPAGE Repository (search AC)
Database constructed and maintained by
SIB
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
Expasy web server