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Searching in 'World-2DPAGE Repository [0027]' for entry matching: P46412 World-2DPAGE Repository (0027):  P46412 P46412 General information about the entry View entry in simple text format Entry name GPX3_MOUSE Primary accession number P46412 integrated into World-2DPAGE Repository (0027) on  September 30, 2010 (release 1) 2D Annotations were last modified on June 21, 2011 (version 2) General Annotations were last modified on  November 23, 2011 (version 2) Name and origin of the protein Description RecName: Full=Glutathione peroxidase 3; Short=GPx-3; Short=GSHPx-3; EC=1.11.1.9; AltName: Full=Plasma glutathione peroxidase; Short=GPx-P; Short=GSHPx-P; Flags: Precursor;. Gene name Name=Gpx3 Annotated species Mus musculus (Mouse) [TaxID: 10090] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/prca.201000103; Blutke A., Block C., Berendt F., Herbach N., Kemter E., Amann K., Frolich T., Arnold G.J., Wanke R. ''Differential glomerular proteome analysis of two murine nephropathy models at onset of albuminuria'' Proteomics - Clinical Applications 5(6):375-381 (2011) 2D PAGE maps for identified proteins How to interpret a protein GIPRDN_4-7 {glomerular protein lysates of a GIPRdn-tg animal} Mus musculus (Mouse)   map experimental info   GIPRDN_4-7 MAP LOCATIONS: SPOT 34: pI=5.66; Mw=22000   [identification data] EXPRESSION: SPOT 34: Avg ratio GIPRdn-tg vs. control=2.32 (p-value=0.0094) [1]. IDENTIFICATION: SPOT 34: SeqCov=32%. Mascot protein score=241 [1]. MAPPING (identification): SPOT 34: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Andreas Blutke, Institute of Veterinary Pathology, University Munich, Germany Cross-references UniProtKB/Swiss-Prot P46412; GPX3_MOUSE. World-2DPAGE Repository P46412; GPX3_MOUSE. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name GPX3_MOUSE Primary accession number P46412 Secondary accession number(s) Q5XKR0 Sequence was last modified on  February 26, 2008 (version 2) Annotations were last modified on  November 16, 2011 (version 106) Name and origin of the protein Description RecName: Full=Glutathione peroxidase 3; Short=GPx-3; Short=GSHPx-3; EC=1.11.1.9; AltName: Full=Plasma glutathione peroxidase; Short=GPx-P; Short=GSHPx-P; Flags: Precursor; Gene name Name=Gpx3 Encoded on Name=Gpx3 Keywords Complete proteome; Oxidoreductase; Peroxidase; Reference proteome; Secreted; Selenocysteine; Signal. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U13705; AAA62283.2; -; mRNA EMBL AK002219; BAC55243.1; -; mRNA EMBL AK004942; BAC55250.1; -; mRNA EMBL AK146760; BAE27413.1; -; mRNA EMBL BC003339; AAH03339.1; -; mRNA EMBL BC037027; AAH37027.1; -; mRNA EMBL BC049235; AAH49235.1; -; mRNA EMBL BC061950; AAH61950.1; -; mRNA EMBL X84742; -; NOT_ANNOTATED_CDS; Genomic_DNA IPI IPI00133536; -; . PIR A55086; A55086; . RefSeq NP_001077398.1; NM_001083929.1; . RefSeq NP_032187.2; NM_008161.2; . UniGene Mm.200916; -; . ProteinModelPortal P46412; -; . SMR P46412; 36-221; . STRING P46412; -; . PeroxiBase 3711; MmGPx03; . PRIDE P46412; -; . Ensembl ENSMUST00000082430; ENSMUSP00000081011; ENSMUSG00000018339; . GeneID 14778; -; . KEGG mmu:14778; -; . UCSC uc007iyk.1; mouse; . CTD 2878; -; . MGI MGI:105102; Gpx3; . eggNOG roNOG05196; -; . GeneTree ENSGT00550000074312; -; . HOGENOM HBG648990; -; . HOVERGEN HBG004333; -; . InParanoid P46412; -; . OMA SNVKMDI; -; . OrthoDB EOG4CRM10; -; . PhylomeDB P46412; -; . NextBio 286887; -; . ArrayExpress P46412; -; . Bgee P46412; -; . CleanEx MM_GPX3; -; . Genevestigator P46412; -; . GermOnline ENSMUSG00000018339; Mus musculus; . GO GO:0005615; C:extracellular space; ISS:UniProtKB; . GO GO:0004602; F:glutathione peroxidase activity; ISS:UniProtKB; . GO GO:0008430; F:selenium binding; ISS:UniProtKB; . GO GO:0042744; P:hydrogen peroxide catabolic process; IDA:MGI; . GO GO:0051289; P:protein homotetramerization; ISS:UniProtKB; . InterPro IPR000889; Glutathione_peroxidase; . InterPro IPR012336; Thioredoxin-like_fold; . Gene3D G3DSA:3.40.30.10; Thioredoxin_fold; 1; . KO K00432; -; . PANTHER PTHR11592; Glut_peroxidase; 1; . Pfam PF00255; GSHPx; 1; . PIRSF PIRSF000303; Glutathion_perox; 1; . PRINTS PR01011; GLUTPROXDASE; . SUPFAM SSF52833; Thiordxn-like_fd; 1; . PROSITE PS00460; GLUTATHIONE_PEROXID_1; 1; . PROSITE PS00763; GLUTATHIONE_PEROXID_2; 1; . PROSITE PS51355; GLUTATHIONE_PEROXID_3; 1; . 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