World-2DPAGE Repository

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.

References

[1]	2D-PAGE GEL CHARACTERIZATION DOI=10.1111/j.1471-4159.2010.06719.x; VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M. ''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome'' J of Neurochemistry 113(6):1577-1588 (2010)

2D PAGE maps for identified proteins

How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus

map experimental info

HIPP_SYNAP

MAP LOCATIONS:

SPOT 667:

pI=5.69; Mw=30951

[identification data]

SPOT 671:

pI=5.69; Mw=30951

[identification data]

IDENTIFICATION: SPOT 667: Peptides number=3. SeqCov=11.8%. MOWSE score=7.42E+1 [1]
SPOT 671: Peptides number=10. SeqCov=43.4%. MOWSE score=2.16E+6 [1].
MAPPING (identification):

SPOT 667: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 671: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright

Data from Dr. Willard Freeman, Penn State College of Medicine, USA

Cross-references

UniProtKB/Swiss-Prot

P47756; CAPZB_HUMAN.

2D PAGE maps for identified proteins
How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry name	CAPZB_HUMAN
Primary accession number	P47756
Secondary accession number(s)	Q32Q68 Q5U0L4 Q8TB49 Q9NUC4
Sequence was last modified on	January 23, 2007 (version 4)
Annotations were last modified on	December 14, 2011 (version 113)
Name and origin of the protein
Description	RecName: Full=F-actin-capping protein subunit beta; AltName: Full=CapZ beta;
Gene name	Name=CAPZB
Encoded on	Name=CAPZB
Keywords	Acetylation; Actin capping; Actin-binding; Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Phosphoprotein; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL	U03271; AAA87395.1; -; mRNA
EMBL	BT019470; AAV38277.1; -; mRNA
EMBL	BT019471; AAV38278.1; -; mRNA
EMBL	AL035413; CAI22231.1; -; Genomic_DNA
EMBL	AL359199; CAI22231.1; JOINED; Genomic_DNA
EMBL	AL445163; CAI22231.1; JOINED; Genomic_DNA
EMBL	AL359199; CAH72124.1; -; Genomic_DNA
EMBL	AL035413; CAH72124.1; JOINED; Genomic_DNA
EMBL	AL445163; CAH72124.1; JOINED; Genomic_DNA
EMBL	AL445163; CAH71392.1; -; Genomic_DNA
EMBL	AL035413; CAH71392.1; JOINED; Genomic_DNA
EMBL	AL359199; CAH71392.1; JOINED; Genomic_DNA
EMBL	CH471134; EAW94890.1; -; Genomic_DNA
EMBL	BC024601; AAH24601.1; -; mRNA
EMBL	BC107752; AAI07753.1; -; mRNA
EMBL	BC109241; AAI09242.1; -; mRNA
EMBL	BC109242; AAI09243.1; -; mRNA
IPI	IPI00026185; -; .
IPI	IPI00642256; -; .
RefSeq	NP_001193469.1; NM_001206540.1; .
RefSeq	NP_004921.1; NM_004930.3; .
UniGene	Hs.432760; -; .
UniGene	Hs.661292; -; .
ProteinModelPortal	P47756; -; .
SMR	P47756; 2-251; .
IntAct	P47756; 14; .
MINT	MINT-254051; -; .
STRING	P47756; -; .
PhosphoSite	P47756; -; .
DMDM	13124696; -; .
SWISS-2DPAGE	P47756; -; .
DOSAC-COBS-2DPAGE	P47756; -; .
OGP	P47756; -; .
REPRODUCTION-2DPAGE	IPI00026185; -; .
PRIDE	P47756; -; .
Ensembl	ENST00000264202; ENSP00000264202; ENSG00000077549; .
Ensembl	ENST00000375142; ENSP00000364284; ENSG00000077549; .
GeneID	832; -; .
KEGG	hsa:832; -; .
CTD	832; -; .
GeneCards	GC01M017911; -; .
HGNC	HGNC:1491; CAPZB; .
HPA	HPA031531; -; .
MIM	601572; gene; .
neXtProt	NX_P47756; -; .
PharmGKB	PA26072; -; .
eggNOG	prNOG04826; -; .
GeneTree	ENSGT00390000017957; -; .
HOVERGEN	HBG050789; -; .
OMA	NLLQEVY; -; .
PhylomeDB	P47756; -; .
Reactome	REACT_604; Hemostasis; .
NextBio	3446; -; .
ArrayExpress	P47756; -; .
Bgee	P47756; -; .
CleanEx	HS_CAPZB; -; .
Genevestigator	P47756; -; .
GermOnline	ENSG00000077549; Homo sapiens; .
GO	GO:0005829; C:cytosol; TAS:Reactome; .
GO	GO:0008290; C:F-actin capping protein complex; TAS:ProtInc; .
GO	GO:0071203; C:WASH complex; IDA:UniProtKB; .
GO	GO:0003779; F:actin binding; TAS:ProtInc; .
GO	GO:0030036; P:actin cytoskeleton organization; IEA:InterPro; .
GO	GO:0051693; P:actin filament capping; IEA:UniProtKB-KW; .
GO	GO:0007596; P:blood coagulation; TAS:Reactome; .
GO	GO:0006928; P:cellular component movement; TAS:UniProtKB; .
GO	GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB; .
InterPro	IPR019771; F-actin_capping_bsu_CS; .
InterPro	IPR001698; WASH_F-actin_cap_beta; .
KO	K10365; -; .
PANTHER	PTHR10619; Factin_cap_beta; 1; .
Pfam	PF01115; F_actin_cap_B; 1; .
PRINTS	PR00192; FACTINCAPB; .
PROSITE	PS00231; F_ACTIN_CAPPING_BETA; 1; .

World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

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