World-2DPAGE Repository

RecName: Full=Dihydropyrimidinase-related protein 2; Short=DRP-2; AltName: Full=Collapsin response mediator protein 2; Short=CRMP-2; AltName: Full=Turned on after division 64 kDa protein; Short=TOAD-64;.

Gene name

Name=Dpysl2

Annotated species

Rattus norvegicus (Rat) [TaxID: 10116]

Taxonomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.

References

[1]	2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.200900680; Maurya D.K., Sundaram C.S., Bhargava P. ''Proteome profile of whole cerebellum of the mature rat'' Proteomics 10(23):4311-4319 (2010)

2D PAGE maps for identified proteins

How to interpret a protein

RAT_CEREBELLUM_21D {Proteome of 21 days old rat cerebellum}
Rattus norvegicus (Rat)
Tissue: Cerebellum

map experimental info

RAT_CEREBELLUM_21D

MAP LOCATIONS:

SPOT 2789:

pI=5.71; Mw=73000

[identification data]

SPOT 2802:

pI=6.55; Mw=65000

[identification data]

IDENTIFICATION: SPOT 2789: SeqCov=62%. MascotPMF=214 [1]
SPOT 2802: SeqCov=57%. MascotPMF=206 [1].
MAPPING (identification):

SPOT 2789: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 2802: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India

Cross-references

PRIDE

10017.

UniProtKB/Swiss-Prot

P47942; DPYL2_RAT.

2D PAGE maps for identified proteins
How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry name	DPYL2_RAT
Primary accession number	P47942
Sequence was last modified on	February 1, 1996 (version 1)
Annotations were last modified on	November 16, 2011 (version 102)
Name and origin of the protein
Description	RecName: Full=Dihydropyrimidinase-related protein 2; Short=DRP-2; AltName: Full=Collapsin response mediator protein 2; Short=CRMP-2; AltName: Full=Turned on after division 64 kDa protein; Short=TOAD-64;
Gene name	Name=Dpysl2
Encoded on	Name=Dpysl2
Keywords	Complete proteome; Cytoplasm; Developmental protein; Differentiation; Direct protein sequencing; Neurogenesis; Phosphoprotein; Reference proteome; S-nitrosylation.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL	Z46882; CAA86981.1; -; mRNA
IPI	IPI00870112; -; .
PIR	A59280; S49985; .
RefSeq	NP_001099187.1; NM_001105717.2; .
UniGene	Rn.2889; -; .
ProteinModelPortal	P47942; -; .
SMR	P47942; 14-490; .
IntAct	P47942; 1; .
MINT	MINT-224453; -; .
STRING	P47942; -; .
MEROPS	M38.975; -; .
PhosphoSite	P47942; -; .
World-2DPAGE	0004:P47942; -; .
PRIDE	P47942; -; .
Ensembl	ENSRNOT00000012996; ENSRNOP00000012996; ENSRNOG00000009625; .
GeneID	25416; -; .
KEGG	rno:25416; -; .
CTD	1808; -; .
RGD	2517; Dpysl2; .
eggNOG	maNOG14228; -; .
GeneTree	ENSGT00550000074371; -; .
HOVERGEN	HBG000806; -; .
InParanoid	P47942; -; .
OMA	TEWHKGV; -; .
OrthoDB	EOG48PMJT; -; .
PhylomeDB	P47942; -; .
NextBio	606559; -; .
ArrayExpress	P47942; -; .
Genevestigator	P47942; -; .
GermOnline	ENSRNOG00000009625; Rattus norvegicus; .
GO	GO:0005829; C:cytosol; IDA:RGD; .
GO	GO:0030425; C:dendrite; IDA:RGD; .
GO	GO:0030426; C:growth cone; IDA:RGD; .
GO	GO:0043025; C:neuronal cell body; IDA:RGD; .
GO	GO:0043234; C:protein complex; IDA:RGD; .
GO	GO:0005625; C:soluble fraction; IDA:RGD; .
GO	GO:0019717; C:synaptosome; IDA:RGD; .
GO	GO:0016812; F:hydrolase activity; acting on carbon-nitrogen (but not peptide) bonds; in cyclic amides
IEA:InterPro	.
GO	GO:0005515; F:protein binding; IPI:RGD; .
GO	GO:0021772; P:olfactory bulb development; IEP:RGD; .
GO	GO:0014049; P:positive regulation of glutamate secretion; IDA:RGD; .
GO	GO:0006208; P:pyrimidine base catabolic process; IEA:InterPro; .
GO	GO:0030516; P:regulation of axon extension; NAS:RGD; .
GO	GO:0001975; P:response to amphetamine; IEP:RGD; .
GO	GO:0042220; P:response to cocaine; IEP:RGD; .
GO	GO:0042493; P:response to drug; IEP:RGD; .
GO	GO:0021510; P:spinal cord development; IEP:RGD; .
GO	GO:0048489; P:synaptic vesicle transport; IDA:RGD; .
InterPro	IPR006680; Amidohydro_1; .
InterPro	IPR011778; Hydantoinase/dihydroPyrase; .
InterPro	IPR011059; Metal-dep_hydrolase_composite; .
KO	K07528; -; .
Pfam	PF01979; Amidohydro_1; 1; .
SUPFAM	SSF51338; Metalo_hydrolase; 2; .
TIGRFAMs	TIGR02033; D-hydantoinase; 1; .

World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server

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