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World-2DPAGE Repository

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Searching in 'World-2DPAGE Repository [0030]' for entry matching: P48679

World-2DPAGE Repository (0030):  P48679


General information about the entry
View entry in simple text format
Entry nameLMNA_RAT
Primary accession numberP48679
integrated into World-2DPAGE Repository (0030) on November 9, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Prelamin-A/C; Contains: RecName: Full=Lamin-A/C; Flags: Precursor;.
Gene nameName=Lmna
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C.
''Two-dimensional gel proteome reference map of INS-1E cells''
Proteomics 11(7):1365-1369 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7}
Rattus norvegicus (Rat)
  map experimental info

pI=6.76; Mw=84757  [identification data]

IDENTIFICATION: SPOT 453: Mascot protein score=173. Number of peptides=6 [1].
MAPPING (identification):
SPOT 453: Tandem mass spectrometry [1].

Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium
UniProtKB/Swiss-ProtP48679; LMNA_RAT.
World-2DPAGE RepositoryP48679; LMNA_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameLMNA_RAT
Primary accession numberP48679
Sequence was last modified on February 1, 1996 (version 1)
Annotations were last modified on November 16, 2011 (version 98)
Name and origin of the protein
DescriptionRecName: Full=Prelamin-A/C; Contains: RecName: Full=Lamin-A/C; Flags: Precursor;
Gene nameName=Lmna
Encoded onName=Lmna; Synonyms=Lmn1
KeywordsAcetylation; Alternative splicing; Coiled coil; Complete proteome; Direct protein sequencing; Intermediate filament; Isopeptide bond; Lipoprotein; Methylation; Nucleus; Phosphoprotein; Prenylation; Reference proteome; Ubl conjugation.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLX66870; CAA47342.1; ALT_FRAME; mRNA
EMBLX76297; CAA53945.1; -; mRNA
IPIIPI00201060; -; .
PIRS27267; S27267; .
RefSeqNP_001002016.1; NM_001002016.1; .
UniGeneRn.44161; -; .
ProteinModelPortalP48679; -; .
SMRP48679; 29-65; 313-386; 428-549
IntActP48679; 2; .
STRINGP48679; -; .
PhosphoSiteP48679; -; .
PRIDEP48679; -; .
GeneID60374; -; .
KEGGrno:60374; -; .
UCSCX66870; rat; .
CTD4000; -; .
RGD620456; Lmna; .
GeneTreeENSGT00560000076873; -; .
HOVERGENHBG013015; -; .
InParanoidP48679; -; .
OrthoDBEOG4S4PG2; -; .
NextBio612051; -; .
ArrayExpressP48679; -; .
GenevestigatorP48679; -; .
GermOnlineENSRNOG00000019638; Rattus norvegicus; .
GOGO:0005626; C:insoluble fraction; IDA:RGD; .
GOGO:0005635; C:nuclear envelope; ISS:UniProtKB; .
GOGO:0016363; C:nuclear matrix; IDA:RGD; .
GOGO:0005198; F:structural molecule activity; TAS:RGD; .
GOGO:0006998; P:nuclear envelope organization; TAS:RGD; .
GOGO:0090343; P:positive regulation of cell aging; ISS:UniProtKB; .
GOGO:0007283; P:spermatogenesis; IEP:RGD; .
InterProIPR016044; F; .
InterProIPR001664; IF; .
InterProIPR001322; IF_tail_C; .
InterProIPR018039; Intermediate_filament_CS; .
KOK12641; -; .
PANTHERPTHR23239; IF; 1; .
PfamPF00038; Filament; 1; .
PfamPF00932; IF_tail; 1; .
PROSITEPS00226; IF; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server