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World-2DPAGE Repository

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Searching in 'World-2DPAGE Repository [0019]' for entry matching: P50398

World-2DPAGE Repository (0019):  P50398


General information about the entry
View entry in simple text format
Entry nameGDIA_RAT
Primary accession numberP50398
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Rab GDP dissociation inhibitor alpha; Short=Rab GDI alpha; AltName: Full=Guanosine diphosphate dissociation inhibitor 1; Short=GDI-1;.
Gene nameName=Gdi1
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
  map experimental info

pI=5.36; Mw=41142  [identification data]
pI=5.00; Mw=50536  [identification data]
pI=5.00; Mw=51074  [identification data]
pI=5.00; Mw=51074  [identification data]

IDENTIFICATION: SPOT 372: Peptides number=10. SeqCov=27.7%. MOWSE score=4.19E+5 [1]
SPOT 373: Peptides number=12. SeqCov=38%. MOWSE score=4.11E+9 [1]; SPOT 992: Peptides number=11. SeqCov=33.1%. MOWSE score=5.34E+5 [1]; SPOT 993: Peptides number=10. SeqCov=30.4%. MOWSE score=7.44E+11 [1].
MAPPING (identification):
SPOT 372: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 373: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 992: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 993: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Data from Dr. Willard Freeman, Penn State College of Medicine, USA
UniProtKB/Swiss-ProtP50398; GDIA_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameGDIA_RAT
Primary accession numberP50398
Secondary accession number(s) Q499U0 Q9R274
Sequence was last modified on October 1, 1996 (version 1)
Annotations were last modified on September 21, 2011 (version 83)
Name and origin of the protein
DescriptionRecName: Full=Rab GDP dissociation inhibitor alpha; Short=Rab GDI alpha; AltName: Full=Guanosine diphosphate dissociation inhibitor 1; Short=GDI-1;
Gene nameName=Gdi1
Encoded onName=Gdi1; Synonyms=Rabgdia
KeywordsComplete proteome; Cytoplasm; Direct protein sequencing; GTPase activation; Phosphoprotein; Reference proteome.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLX74402; CAA52413.1; -; mRNA
EMBLU07952; AAB16909.1; -; mRNA
EMBLBC099763; AAH99763.1; -; mRNA
EMBLAF130987; AAD25536.1; -; mRNA
IPIIPI00324986; -; .
PIRA54091; A54091; .
PIRB56024; B56024; .
RefSeqNP_058784.2; NM_017088.2; .
UniGeneRn.4000; -; .
ProteinModelPortalP50398; -; .
SMRP50398; 1-431; .
STRINGP50398; -; .
PhosphoSiteP50398; -; .
World-2DPAGE0004:P50398; -; .
PRIDEP50398; -; .
EnsemblENSRNOT00000056295; ENSRNOP00000053135; ENSRNOG00000037245; .
GeneID25183; -; .
KEGGrno:25183; -; .
UCSCBC072538; rat; .
CTD2664; -; .
RGD2676; Gdi1; .
eggNOGmaNOG16589; -; .
HOVERGENHBG000839; -; .
InParanoidP50398; -; .
OrthoDBEOG4H19VS; -; .
PhylomeDBP50398; -; .
NextBio605677; -; .
ArrayExpressP50398; -; .
GenevestigatorP50398; -; .
GermOnlineENSRNOG00000037245; Rattus norvegicus; .
GOGO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell; .
GOGO:0043234; C:protein complex; IDA:RGD; .
GOGO:0019717; C:synaptosome; IDA:RGD; .
GOGO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW; .
GOGO:0005515; F:protein binding; IPI:RGD; .
GOGO:0005093; F:Rab GDP-dissociation inhibitor activity; IDA:RGD; .
GOGO:0015031; P:protein transport; IEA:InterPro; .
GOGO:0051592; P:response to calcium ion; IDA:RGD; .
InterProIPR018203; GDP_dissociation_inhibitor; .
InterProIPR000806; RabGDI; .
PfamPF00996; GDI; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server