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Searching in 'World-2DPAGE Repository [0014]' for entry matching: P50554 World-2DPAGE Repository (0014):  P50554 P50554 General information about the entry View entry in simple text format Entry name GABT_RAT Primary accession number P50554 integrated into World-2DPAGE Repository (0014) on  October 13, 2008 (release 1) 2D Annotations were last modified on June 1, 2011 (version 3) General Annotations were last modified on  November 25, 2011 (version 2) Name and origin of the protein Description RecName: Full=4-aminobutyrate aminotransferase, mitochondrial; EC=2.6.1.19; AltName: Full=(S)-3-amino-2-methylpropionate transaminase; EC=2.6.1.22; AltName: Full=GABA aminotransferase; Short=GABA-AT; AltName: Full=Gamma-amino-N-butyrate transaminase; Short=GABA transaminase; Short=GABA-T; AltName: Full=L-AIBAT; Contains: RecName: Full=4-aminobutyrate aminotransferase, brain isoform; Contains: RecName: Full=4-aminobutyrate aminotransferase, liver isoform; Flags: Precursor;. Gene name Name=Abat Synonyms=Gabat Annotated species Rattus norvegicus (Rat) [TaxID: 10116] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.200900680; Maurya D.K., Sundaram C.S., Bhargava P. ''Proteome profile of whole cerebellum of the mature rat'' Proteomics 10(23):4311-4319 (2010) 2D PAGE maps for identified proteins How to interpret a protein RAT_CEREBELLUM_21D {Proteome of 21 days old rat cerebellum} Rattus norvegicus (Rat) Tissue: Cerebellum   map experimental info   RAT_CEREBELLUM_21D MAP LOCATIONS: SPOT 2895: pI=7.67; Mw=49000   [identification data] IDENTIFICATION: SPOT 2895: SeqCov=53%. MascotPMF=213 [1]. MAPPING (identification): SPOT 2895: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India Cross-references PRIDE 10017. UniProtKB/Swiss-Prot P50554; GABT_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name GABT_RAT Primary accession number P50554 Secondary accession number(s) O70539 Q66HM1 Sequence was last modified on  January 9, 2007 (version 3) Annotations were last modified on  November 16, 2011 (version 99) Name and origin of the protein Description RecName: Full=4-aminobutyrate aminotransferase, mitochondrial; EC=2.6.1.19; AltName: Full=(S)-3-amino-2-methylpropionate transaminase; EC=2.6.1.22; AltName: Full=GABA aminotransferase; Short=GABA-AT; AltName: Full=Gamma-amino-N-butyrate transaminase; Short=GABA transaminase; Short=GABA-T; AltName: Full=L-AIBAT; Contains: RecName: Full=4-aminobutyrate aminotransferase, brain isoform; Contains: RecName: Full=4-aminobutyrate aminotransferase, liver isoform; Flags: Precursor; Gene name Name=Abat Synonyms=Gabat Encoded on Name=Abat; Synonyms=Gabat Keywords Acetylation; Aminotransferase; Complete proteome; Direct protein sequencing; Disulfide bond; Mitochondrion; Neurotransmitter degradation; Pyridoxal phosphate; Reference proteome; Transferase; Transit peptide. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U29701; AAA70415.1; -; mRNA EMBL D87839; BAA25570.1; -; mRNA EMBL BC081787; AAH81787.1; -; mRNA IPI IPI00199426; -; . PIR I56502; I56502; . RefSeq NP_112265.1; NM_031003.1; . UniGene Rn.10090; -; . ProteinModelPortal P50554; -; . SMR P50554; 39-499; . STRING P50554; -; . PhosphoSite P50554; -; . World-2DPAGE 0004:P50554; -; . PRIDE P50554; -; . Ensembl ENSRNOT00000003633; ENSRNOP00000003633; ENSRNOG00000002636; . GeneID 81632; -; . KEGG rno:81632; -; . NMPDR fig|10116.3.peg.4435; -; . UCSC NM_031003; rat; . CTD 18; -; . RGD 620948; Abat; . eggNOG roNOG08236; -; . GeneTree ENSGT00550000074885; -; . HOVERGEN HBG000634; -; . InParanoid P50554; -; . OMA ATGKFWA; -; . OrthoDB EOG441QB6; -; . PhylomeDB P50554; -; . NextBio 615107; -; . ArrayExpress P50554; -; . Genevestigator P50554; -; . GermOnline ENSRNOG00000002636; Rattus norvegicus; . GO GO:0032144; C:4-aminobutyrate transaminase complex; ISS:UniProtKB; . GO GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell; . GO GO:0019717; C:synaptosome; IDA:RGD; . GO GO:0047298; F:(S)-3-amino-2-methylpropionate transaminase activity; IEA:EC; . GO GO:0003867; F:4-aminobutyrate transaminase activity; IDA:RGD; . GO GO:0042803; F:protein homodimerization activity; ISS:UniProtKB; . GO GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB; . GO GO:0032145; F:succinate-semialdehyde dehydrogenase binding; ISS:UniProtKB; . GO GO:0048148; P:behavioral response to cocaine; ISS:UniProtKB; . GO GO:0007620; P:copulation; IMP:RGD; . GO GO:0009450; P:gamma-aminobutyric acid catabolic process; IC:UniProtKB; . GO GO:0007626; P:locomotory behavior; IMP:RGD; . GO GO:0045776; P:negative regulation of blood pressure; IMP:RGD; . GO GO:0042135; P:neurotransmitter catabolic process; IC:UniProtKB; . GO GO:0042493; P:response to drug; IDA:RGD; . GO GO:0045471; P:response to ethanol; IDA:RGD; . GO GO:0001666; P:response to hypoxia; IMP:RGD; . GO GO:0010039; P:response to iron ion; IDA:RGD; . GO GO:0035094; P:response to nicotine; IMP:RGD; . InterPro IPR004631; 4NH2But_aminotransferase_euk; . InterPro IPR005814; Aminotrans_3; . InterPro IPR015424; PyrdxlP-dep_Trfase_major_dom; . InterPro IPR015421; PyrdxlP-dep_Trfase_major_sub1; . InterPro IPR015422; PyrdxlP-dep_Trfase_major_sub2; . Gene3D G3DSA:3.40.640.10; PyrdxlP-dep_Trfase_major_sub1; 1; . Gene3D G3DSA:3.90.1150.10; PyrdxlP-dep_Trfase_major_sub2; 2; . KO K13524; -; . PANTHER PTHR11986; Aminotrans_3; 1; . PANTHER PTHR11986:SF6; GABAtrns_euk; 1; . Pfam PF00202; Aminotran_3; 1; . SUPFAM SSF53383; PyrdxlP-dep_Trfase_major; 1; . TIGRFAMs TIGR00699; GABAtrns_euk; 1; . PROSITE PS00600; AA_TRANSFER_CLASS_3; 1; . World-2DPAGE Repository (search AC)