World-2DPAGE Repository

RecName: Full=Alcohol dehydrogenase [NADP+]; EC=1.1.1.2; AltName: Full=3-DG-reducing enzyme; AltName: Full=Aldehyde reductase; AltName: Full=Aldo-keto reductase family 1 member A1;.

Gene name

Name=Akr1a1
Synonyms=Alr

Annotated species

Rattus norvegicus (Rat) [TaxID: 10116]

Taxonomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.

References

[1]	MAPPING ON GEL PubMed=19343716; DOI=10.1002/pmic.200800664; [NCBI, EBI, Israel, Japan] Maurya D.K., Sundaram C.S., Bhargava P. ''Proteome profile of the mature rat olfactory bulb'' Proteomics 9(1):2593-2599 (2009)

2D PAGE maps for identified proteins

How to interpret a protein

OB21DSUB {2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb

map experimental info

OB21DSUB

MAP LOCATIONS:

SPOT 491:

pI=6.92; Mw=40000

[identification data]

MAPPING (identification):

SPOT 491: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India

Cross-references

UniProtKB/Swiss-Prot

P51635; AK1A1_RAT.

2D PAGE maps for identified proteins
How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry name	AK1A1_RAT
Primary accession number	P51635
Sequence was last modified on	January 23, 2007 (version 2)
Annotations were last modified on	November 16, 2011 (version 82)
Name and origin of the protein
Description	RecName: Full=Alcohol dehydrogenase [NADP+]; EC=1.1.1.2; AltName: Full=3-DG-reducing enzyme; AltName: Full=Aldehyde reductase; AltName: Full=Aldo-keto reductase family 1 member A1;
Gene name	Name=Akr1a1 Synonyms=Alr
Encoded on	Name=Akr1a1; Synonyms=Alr
Keywords	Acetylation; Complete proteome; Direct protein sequencing; Glycation; Glycoprotein; NADP; Oxidoreductase; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL	D10854; BAA01627.1; -; mRNA
EMBL	BC059133; AAH59133.1; -; mRNA
IPI	IPI00230859; -; .
PIR	JN0629; JN0629; .
RefSeq	NP_112262.1; NM_031000.3; .
UniGene	Rn.835; -; .
ProteinModelPortal	P51635; -; .
SMR	P51635; 3-325; .
STRING	P51635; -; .
World-2DPAGE	0004:P51635; -; .
PRIDE	P51635; -; .
Ensembl	ENSRNOT00000023072; ENSRNOP00000023072; ENSRNOG00000016727; .
GeneID	78959; -; .
KEGG	rno:78959; -; .
UCSC	NM_031000; rat; .
CTD	10327; -; .
RGD	68346; Akr1a1; .
eggNOG	roNOG06774; -; .
GeneTree	ENSGT00570000078918; -; .
HOVERGEN	HBG000020; -; .
InParanoid	P51635; -; .
OMA	DALNKNW; -; .
OrthoDB	EOG4J118N; -; .
PhylomeDB	P51635; -; .
NextBio	614380; -; .
ArrayExpress	P51635; -; .
Genevestigator	P51635; -; .
GermOnline	ENSRNOG00000016727; Rattus norvegicus; .
GO	GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC; .
InterPro	IPR001395; Aldo/ket_red; .
InterPro	IPR018170; Aldo/ket_reductase_CS; .
InterPro	IPR020471; Aldo/keto_reductase_subgr; .
InterPro	IPR023210; NADP_OxRdtase_dom; .
Gene3D	G3DSA:3.20.20.100; Aldo/ket_red; 1; .
KO	K00002; -; .
PANTHER	PTHR11732; Aldo/ket_red; 1; .
Pfam	PF00248; Aldo_ket_red; 1; .
PIRSF	PIRSF000097; AKR; 1; .
PRINTS	PR00069; ALDKETRDTASE; .
SUPFAM	SSF51430; Aldo/ket_red; 1; .
PROSITE	PS00798; ALDOKETO_REDUCTASE_1; 1; .
PROSITE	PS00062; ALDOKETO_REDUCTASE_2; 1; .
PROSITE	PS00063; ALDOKETO_REDUCTASE_3; 1; .

World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server

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