Attention: World-2DPAGE is no longer maintained.

World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0030]' for entry matching: P5CS_MOUSE World-2DPAGE Repository (0030):  P5CS_MOUSE P5CS_MOUSE General information about the entry View entry in simple text format Entry name P5CS_MOUSE Primary accession number Q9Z110 integrated into World-2DPAGE Repository (0030) on  November 9, 2010 (release 1) 2D Annotations were last modified on June 21, 2011 (version 2) General Annotations were last modified on  November 23, 2011 (version 2) Name and origin of the protein Description RecName: Full=Delta-1-pyrroline-5-carboxylate synthase; Short=P5CS; AltName: Full=Aldehyde dehydrogenase family 18 member A1; Includes: RecName: Full=Glutamate 5-kinase; Short=GK; EC=2.7.2.11; AltName: Full=Gamma-glutamyl kinase; Includes: RecName: Full=Gamma-glutamyl phosphate reductase; Short=GPR; EC=1.2.1.41; AltName: Full=Glutamate-5-semialdehyde dehydrogenase; AltName: Full=Glutamyl-gamma-semialdehyde dehydrogenase;. Gene name Name=Aldh18a1 Synonyms=P5cs, Pycs Annotated species Rattus norvegicus (Rat) [TaxID: 10116] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000006; D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C. ''Two-dimensional gel proteome reference map of INS-1E cells'' Proteomics 11(7):1365-1369 (2011) 2D PAGE maps for identified proteins How to interpret a protein RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7} Rattus norvegicus (Rat)   map experimental info   RAT_INS1E_4-7 MAP LOCATIONS: SPOT 400: pI=6.70; Mw=86894   [identification data] IDENTIFICATION: SPOT 400: Mascot protein score=92. Number of peptides=3 [1]. MAPPING (identification): SPOT 400: Tandem mass spectrometry [1]. Copyright Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium Cross-references UniProtKB/Swiss-Prot Q9Z110; P5CS_MOUSE. World-2DPAGE Repository Q9Z110; P5CS_MOUSE. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name P5CS_MOUSE Primary accession number Q9Z110 Secondary accession number(s) Q8BGM2 Q9R1P6 Sequence was last modified on  July 27, 2011 (version 2) Annotations were last modified on  November 16, 2011 (version 110) Name and origin of the protein Description RecName: Full=Delta-1-pyrroline-5-carboxylate synthase; Short=P5CS; AltName: Full=Aldehyde dehydrogenase family 18 member A1; Includes: RecName: Full=Glutamate 5-kinase; Short=GK; EC=2.7.2.11; AltName: Full=Gamma-glutamyl kinase; Includes: RecName: Full=Gamma-glutamyl phosphate reductase; Short=GPR; EC=1.2.1.41; AltName: Full=Glutamate-5-semialdehyde dehydrogenase; AltName: Full=Glutamyl-gamma-semialdehyde dehydrogenase; Gene name Name=Aldh18a1 Synonyms=P5cs, Pycs Encoded on Name=Aldh18a1; Synonyms=P5cs, Pycs Keywords Alternative splicing; Amino-acid biosynthesis; ATP-binding; Complete proteome; Kinase; Membrane; Mitochondrion; Mitochondrion inner membrane; Multifunctional enzyme; NADP; Nucleotide-binding; Oxidoreductase; Proline biosynthesis; Reference proteome; Transferase. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF056573; AAD17517.1; -; mRNA EMBL AF056574; AAD17518.1; -; mRNA EMBL AK151072; BAE30088.1; -; mRNA EMBL AK153946; BAE32270.1; -; mRNA EMBL AK168905; BAE40719.1; -; mRNA EMBL CH466534; EDL41837.1; -; Genomic_DNA EMBL BC033427; AAH33427.1; -; mRNA EMBL BC037699; AAH37699.1; -; mRNA IPI IPI00129350; -; . IPI IPI00221398; -; . RefSeq NP_062672.2; NM_019698.2; . RefSeq NP_705782.2; NM_153554.2; . UniGene Mm.233117; -; . HSSP Q9WYC9; 1O20; . ProteinModelPortal Q9Z110; -; . SMR Q9Z110; 69-358; 362-793; . STRING Q9Z110; -; . PhosphoSite Q9Z110; -; . PRIDE Q9Z110; -; . Ensembl ENSMUST00000025979; ENSMUSP00000025979; ENSMUSG00000025007; . GeneID 56454; -; . KEGG mmu:56454; -; . UCSC uc008hkw.2; mouse; . MGI MGI:1888908; Aldh18a1; . GeneTree ENSGT00500000044903; -; . HOGENOM HBG318080; -; . HOVERGEN HBG007911; -; . InParanoid Q9Z110; -; . OrthoDB EOG4ZKJKN; -; . PhylomeDB Q9Z110; -; . NextBio 312680; -; . ArrayExpress Q9Z110; -; . Bgee Q9Z110; -; . CleanEx MM_ALDH18A1; -; . Genevestigator Q9Z110; -; . GermOnline ENSMUSG00000025007; Mus musculus; . GO GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0004349; F:glutamate 5-kinase activity; IDA:MGI; . GO GO:0004350; F:glutamate-5-semialdehyde dehydrogenase activity; IEA:EC; . GO GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW; . InterPro IPR016161; Ald_DH/histidinol_DH; . InterPro IPR016163; Ald_DH_C; . InterPro IPR016162; Ald_DH_N; . InterPro IPR015590; Aldehyde_DH_dom; . InterPro IPR001048; Asp/Glu/Uridylate_kinase; . InterPro IPR000965; G-glutamylP_reductase; . InterPro IPR020593; G-glutamylP_reductase_CS; . InterPro IPR001057; Glu/AcGlu_kinase; . InterPro IPR019797; Glutamate_5-kinase_CS; . InterPro IPR005766; P5_carboxy_syn; . Gene3D G3DSA:3.40.1160.10; Aa_kinase; 1; . Gene3D G3DSA:3.40.309.10; Aldehyde_dehydrogenase_C; 1; . Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 2; . KO K12657; -; . Pfam PF00696; AA_kinase; 1; . Pfam PF00171; Aldedh; 1; . PIRSF PIRSF036429; P5C_syn; 1; . PRINTS PR00474; GLU5KINASE; . SUPFAM SSF53633; Aa_kinase; 1; . SUPFAM SSF53720; Aldehyde_DH/Histidinol_DH; 1; . TIGRFAMs TIGR01092; P5CS; 1; . TIGRFAMs TIGR00407; ProA; 1; . PROSITE PS00902; GLUTAMATE_5_KINASE; 1; . PROSITE PS01223; PROA; 1; . World-2DPAGE Repository (search AC)