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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0019]' for entry matching: P62714 World-2DPAGE Repository (0019):  P62714 P62714 General information about the entry View entry in simple text format Entry name PP2AB_HUMAN Primary accession number P62714 Secondary accession number(s) Q6FHK5 integrated into World-2DPAGE Repository (0019) on  December 9, 2009 (release 1) 2D Annotations were last modified on May 30, 2011 (version 2) General Annotations were last modified on  January 13, 2012 (version 2) Name and origin of the protein Description RecName: Full=Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; Short=PP2A-beta; EC=3.1.3.16;. Gene name Name=PPP2CB Annotated species Rattus norvegicus (Rat) [TaxID: 10116] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1111/j.1471-4159.2010.06719.x; VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M. ''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome'' J of Neurochemistry 113(6):1577-1588 (2010) 2D PAGE maps for identified proteins How to interpret a protein HIPP_SYNAP {Rat hippocampal synaptoproteome} Rattus norvegicus (Rat) Tissue: Hippocampus   map experimental info   HIPP_SYNAP MAP LOCATIONS: SPOT 625: pI=5.21; Mw=36122   [identification data] SPOT 627: pI=5.21; Mw=36122   [identification data] IDENTIFICATION: SPOT 625: Peptides number=6. SeqCov=20.4%. MOWSE score=1.92E+3 [1] SPOT 627: Peptides number=8. SeqCov=28.5%. MOWSE score=2.36E+5 [1]. MAPPING (identification): SPOT 625: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 627: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Willard Freeman, Penn State College of Medicine, USA Cross-references UniProtKB/Swiss-Prot P62714; PP2AB_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_12 Entry name PP2AB_HUMAN Primary accession number P62714 Secondary accession number(s) D3DSV4 P11082 Q6FHK5 Sequence was last modified on  July 19, 2004 (version 1) Annotations were last modified on  December 14, 2011 (version 86) Name and origin of the protein Description RecName: Full=Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; Short=PP2A-beta; EC=3.1.3.16; Gene name Name=PPP2CB Encoded on Name=PPP2CB Keywords Centromere; Chromosome; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Hydrolase; Iron; Manganese; Metal-binding; Methylation; Nucleus; Phosphoprotein; Protein phosphatase; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X12656; CAA31183.1; -; mRNA EMBL CR541747; CAG46547.1; -; mRNA EMBL J03805; AAB38020.1; -; mRNA EMBL CH471080; EAW63434.1; -; Genomic_DNA EMBL CH471080; EAW63435.1; -; Genomic_DNA EMBL CH471080; EAW63436.1; -; Genomic_DNA EMBL BC012022; AAH12022.1; -; mRNA EMBL M60484; AAA36467.1; -; Genomic_DNA IPI IPI00429689; -; . PIR B37135; PAHU2B; . RefSeq NP_001009552.1; NM_001009552.1; . UniGene Hs.491440; -; . ProteinModelPortal P62714; -; . SMR P62714; 6-293; . IntAct P62714; 56; . MINT MINT-1348293; -; . STRING P62714; -; . PhosphoSite P62714; -; . DMDM 50402236; -; . OGP P62714; -; . REPRODUCTION-2DPAGE IPI00429689; -; . PRIDE P62714; -; . Ensembl ENST00000221138; ENSP00000221138; ENSG00000104695; . Ensembl ENST00000397308; ENSP00000380475; ENSG00000104695; . Ensembl ENST00000406655; ENSP00000384493; ENSG00000104695; . GeneID 5516; -; . KEGG hsa:5516; -; . UCSC uc003xik.1; human; . CTD 5516; -; . GeneCards GC08M029189; -; . H-InvDB HIX0007439; -; . HGNC HGNC:9300; PPP2CB; . HPA CAB018600; -; . MIM 176916; gene; . neXtProt NX_P62714; -; . PharmGKB PA33664; -; . eggNOG prNOG16980; -; . HOGENOM HBG716770; -; . HOVERGEN HBG000216; -; . InParanoid P62714; -; . OMA VENDIFC; -; . OrthoDB EOG4Q58PR; -; . PhylomeDB P62714; -; . Pathway_Interaction_DB tgfbrpathway; TGF-beta receptor signaling; . Reactome REACT_111102; Signal Transduction; . Reactome REACT_111217; Metabolism; . Reactome REACT_152; Cell Cycle; Mitotic; . Reactome REACT_383; DNA Replication; . Reactome REACT_474; Metabolism of carbohydrates; . Reactome REACT_604; Hemostasis; . Reactome REACT_6900; Immune System; . DrugBank DB00163; Vitamin E; . NextBio 21334; -; . ArrayExpress P62714; -; . Bgee P62714; -; . CleanEx HS_PPP2CB; -; . Genevestigator P62714; -; . GermOnline ENSG00000104695; Homo sapiens; . GO GO:0000775; C:chromosome; centromeric region; IEA:UniProtKB-SubCell GO GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell; . GO GO:0005634; C:nucleus; IEA:UniProtKB-SubCell; . GO GO:0000159; C:protein phosphatase type 2A complex; TAS:UniProtKB; . GO GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell; . GO GO:0046872; F:metal ion binding; IEA:UniProtKB-KW; . GO GO:0006470; P:protein dephosphorylation; TAS:UniProtKB; . InterPro IPR004843; Metallo_PEstase_dom; . InterPro IPR006186; Ser/Thr-sp_prot-phosphatase; . KO K04382; -; . Pfam PF00149; Metallophos; 1; . PRINTS PR00114; STPHPHTASE; . SMART SM00156; PP2Ac; 1; . PROSITE PS00125; SER_THR_PHOSPHATASE; 1; . World-2DPAGE Repository (search AC)