World-2DPAGE Repository
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World-2DPAGE Repository
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SWISS-2DPAGE
World-2DPAGE Portal
Exclude local DBs
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Searching in 'World-2DPAGE Repository [0019]' for entry
matching:
P62714
World-2DPAGE Repository
(0019):
P62714
P62714
General information about the entry
View entry in simple text format
Entry name
PP2AB_HUMAN
Primary accession number
P62714
Secondary accession number(s)
Q6FHK5
integrated into World-2DPAGE Repository (0019) on
December 9, 2009 (release 1)
2D Annotations were last modified on
May 30, 2011 (version 2)
General Annotations were last modified on
January 13, 2012 (version 2)
Name and origin of the protein
Description
RecName: Full=Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; Short=PP2A-beta; EC=3.1.3.16;.
Gene name
Name=PPP2CB
Annotated species
Rattus norvegicus (Rat) [TaxID:
10116
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]
2D-PAGE GEL CHARACTERIZATION
DOI=
10.1111/j.1471-4159.2010.06719.x
;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein
HIPP_SYNAP
{Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
map experimental info
HIPP_SYNAP
MAP LOCATIONS:
SPOT 625
:
pI=5.21; Mw=36122
[identification data]
SPOT 627
:
pI=5.21; Mw=36122
[identification data]
IDENTIFICATION:
SPOT 625: Peptides number=6. SeqCov=20.4%. MOWSE score=1.92E+3 [
1
]
SPOT 627: Peptides number=8. SeqCov=28.5%. MOWSE score=2.36E+5 [
1
].
MAPPING (identification):
SPOT
625
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
];
SPOT
627
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
].
Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-Prot
P62714; PP2AB_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
2011_12
Entry name
PP2AB_HUMAN
Primary accession number
P62714
Secondary accession number(s)
D3DSV4 P11082 Q6FHK5
Sequence was last modified on
July 19, 2004 (version 1)
Annotations were last modified on
December 14, 2011 (version 86)
Name and origin of the protein
Description
RecName: Full=Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; Short=PP2A-beta; EC=3.1.3.16;
Gene name
Name=PPP2CB
Encoded on
Name=PPP2CB
Keywords
Centromere
;
Chromosome
;
Complete proteome
;
Cytoplasm
;
Cytoskeleton
;
Direct protein sequencing
;
Hydrolase
;
Iron
;
Manganese
;
Metal-binding
;
Methylation
;
Nucleus
;
Phosphoprotein
;
Protein phosphatase
;
Reference proteome
.
Copyright
Copyrighted by the UniProt Consortium, see
https://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
X12656; CAA31183.1
; -; mRNA
EMBL
CR541747; CAG46547.1
; -; mRNA
EMBL
J03805; AAB38020.1
; -; mRNA
EMBL
CH471080; EAW63434.1
; -; Genomic_DNA
EMBL
CH471080; EAW63435.1
; -; Genomic_DNA
EMBL
CH471080; EAW63436.1
; -; Genomic_DNA
EMBL
BC012022; AAH12022.1
; -; mRNA
EMBL
M60484; AAA36467.1
; -; Genomic_DNA
IPI
IPI00429689; -
; .
PIR
B37135; PAHU2B
; .
RefSeq
NP_001009552.1; NM_001009552.1
; .
UniGene
Hs.491440; -
; .
ProteinModelPortal
P62714; -
; .
SMR
P62714; 6-293
; .
IntAct
P62714; 56
; .
MINT
MINT-1348293; -
; .
STRING
P62714; -
; .
PhosphoSite
P62714; -
; .
DMDM
50402236; -
; .
OGP
P62714; -
; .
REPRODUCTION-2DPAGE
IPI00429689; -
; .
PRIDE
P62714; -
; .
Ensembl
ENST00000221138; ENSP00000221138
; ENSG00000104695; .
Ensembl
ENST00000397308; ENSP00000380475
; ENSG00000104695; .
Ensembl
ENST00000406655; ENSP00000384493
; ENSG00000104695; .
GeneID
5516; -
; .
KEGG
hsa:5516; -
; .
UCSC
uc003xik.1; human
; .
CTD
5516; -
; .
GeneCards
GC08M029189; -
; .
H-InvDB
HIX0007439; -
; .
HGNC
HGNC:9300; PPP2CB
; .
HPA
CAB018600; -
; .
MIM
176916; gene
; .
neXtProt
NX_P62714; -
; .
PharmGKB
PA33664; -
; .
eggNOG
prNOG16980; -
; .
HOGENOM
HBG716770; -
; .
HOVERGEN
HBG000216; -
; .
InParanoid
P62714; -
; .
OMA
VENDIFC; -
; .
OrthoDB
EOG4Q58PR; -
; .
PhylomeDB
P62714; -
; .
Pathway_Interaction_DB
tgfbrpathway; TGF-beta receptor signaling
; .
Reactome
REACT_111102; Signal Transduction
; .
Reactome
REACT_111217; Metabolism
; .
Reactome
REACT_152; Cell Cycle
; Mitotic; .
Reactome
REACT_383; DNA Replication
; .
Reactome
REACT_474; Metabolism of carbohydrates
; .
Reactome
REACT_604; Hemostasis
; .
Reactome
REACT_6900; Immune System
; .
DrugBank
DB00163; Vitamin E
; .
NextBio
21334; -
; .
ArrayExpress
P62714; -
; .
Bgee
P62714; -
; .
CleanEx
HS_PPP2CB; -
; .
Genevestigator
P62714; -
; .
GermOnline
ENSG00000104695; Homo sapiens
; .
GO
GO:0000775; C:chromosome
; centromeric region; IEA:UniProtKB-SubCell
GO
GO:0005737; C:cytoplasm
; IEA:UniProtKB-SubCell; .
GO
GO:0005634; C:nucleus
; IEA:UniProtKB-SubCell; .
GO
GO:0000159; C:protein phosphatase type 2A complex
; TAS:UniProtKB; .
GO
GO:0000922; C:spindle pole
; IEA:UniProtKB-SubCell; .
GO
GO:0046872; F:metal ion binding
; IEA:UniProtKB-KW; .
GO
GO:0006470; P:protein dephosphorylation
; TAS:UniProtKB; .
InterPro
IPR004843; Metallo_PEstase_dom
; .
InterPro
IPR006186; Ser/Thr-sp_prot-phosphatase
; .
KO
K04382; -
; .
Pfam
PF00149; Metallophos
; 1; .
PRINTS
PR00114; STPHPHTASE
; .
SMART
SM00156; PP2Ac
; 1; .
PROSITE
PS00125; SER_THR_PHOSPHATASE
; 1; .
World-2DPAGE Repository (search AC)
Database constructed and maintained by
SIB
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
Expasy web server