World-2DPAGE Repository

RecName: Full=V-type proton ATPase subunit B, brain isoform; Short=V-ATPase subunit B 2; AltName: Full=Endomembrane proton pump 58 kDa subunit; AltName: Full=Vacuolar proton pump subunit B 2;.

Gene name

Name=Atp6v1b2
Synonyms=Atp6b2, Vat2

Annotated species

Rattus norvegicus (Rat) [TaxID: 10116]

Taxonomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.

References

[1]	MAPPING ON GEL PubMed=19343716; DOI=10.1002/pmic.200800664; [NCBI, EBI, Israel, Japan] Maurya D.K., Sundaram C.S., Bhargava P. ''Proteome profile of the mature rat olfactory bulb'' Proteomics 9(1):2593-2599 (2009)

2D PAGE maps for identified proteins

How to interpret a protein

OB21DSUB {2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb

map experimental info

OB21DSUB

MAP LOCATIONS:

SPOT 335:

pI=5.59; Mw=51000

[identification data]

SPOT 336:

pI=5.88; Mw=51000

[identification data]

MAPPING (identification):

SPOT 335: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 336: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India

Cross-references

UniProtKB/Swiss-Prot

P62815; VATB2_RAT.

2D PAGE maps for identified proteins
How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry name	VATB2_RAT
Primary accession number	P62815
Secondary accession number(s)	O09045 P50517
Sequence was last modified on	August 16, 2004 (version 1)
Annotations were last modified on	November 16, 2011 (version 70)
Name and origin of the protein
Description	RecName: Full=V-type proton ATPase subunit B, brain isoform; Short=V-ATPase subunit B 2; AltName: Full=Endomembrane proton pump 58 kDa subunit; AltName: Full=Vacuolar proton pump subunit B 2;
Gene name	Name=Atp6v1b2 Synonyms=Atp6b2, Vat2
Encoded on	Name=Atp6v1b2; Synonyms=Atp6b2, Vat2
Keywords	Complete proteome; Direct protein sequencing; Hydrogen ion transport; Hydrolase; Ion transport; Membrane; Phosphoprotein; Reference proteome; Transport.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL	Y12635; CAA73183.1; -; mRNA
EMBL	BC085714; AAH85714.1; -; mRNA
IPI	IPI00199305; -; .
RefSeq	NP_476561.1; NM_057213.2; .
UniGene	Rn.8109; -; .
ProteinModelPortal	P62815; -; .
SMR	P62815; 53-507; .
IntAct	P62815; 1; .
STRING	P62815; -; .
PhosphoSite	P62815; -; .
World-2DPAGE	0004:P62815; -; .
PRIDE	P62815; -; .
Ensembl	ENSRNOT00000015931; ENSRNOP00000015931; ENSRNOG00000011891; .
GeneID	117596; -; .
KEGG	rno:117596; -; .
UCSC	NM_057213; rat; .
CTD	526; -; .
RGD	620284; Atp6v1b2; .
eggNOG	roNOG17349; -; .
GeneTree	ENSGT00550000074724; -; .
HOVERGEN	HBG002176; -; .
InParanoid	P62815; -; .
OrthoDB	EOG4HMJ93; -; .
PhylomeDB	P62815; -; .
NextBio	620435; -; .
ArrayExpress	P62815; -; .
Genevestigator	P62815; -; .
GermOnline	ENSRNOG00000011891; Rattus norvegicus; .
GO	GO:0005829; C:cytosol; ISS:UniProtKB; .
GO	GO:0016021; C:integral to membrane; IDA:RGD; .
GO	GO:0042470; C:melanosome; IEA:UniProtKB-SubCell; .
GO	GO:0005886; C:plasma membrane; ISS:UniProtKB; .
GO	GO:0033180; C:proton-transporting V-type ATPase; V1 domain; IEA:InterPro
GO	GO:0005773; C:vacuole; TAS:GOC; .
GO	GO:0005524; F:ATP binding; IEA:InterPro; .
GO	GO:0046933; F:hydrogen ion transporting ATP synthase activity; rotational mechanism; IEA:InterPro
GO	GO:0046961; F:proton-transporting ATPase activity; rotational mechanism; IEA:InterPro
GO	GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro; .
GO	GO:0007035; P:vacuolar acidification; TAS:RGD; .
InterPro	IPR020003; ATPase_a/bsu_AS; .
InterPro	IPR000793; ATPase_F1/V1/A1-cplx_a/bsu_C; .
InterPro	IPR004100; ATPase_F1/V1/A1-cplx_a/bsu_N; .
InterPro	IPR000194; ATPase_F1/V1/A1_a/bsu_nucl-bd; .
InterPro	IPR005723; ATPase_V1-cplx_bsu; .
InterPro	IPR022879; V-ATPase_su_B/beta; .
KO	K02147; -; .
Pfam	PF00006; ATP-synt_ab; 1; .
Pfam	PF00306; ATP-synt_ab_C; 1; .
Pfam	PF02874; ATP-synt_ab_N; 1; .
TIGRFAMs	TIGR01040; V-ATPase_V1_B; 1; .
PROSITE	PS00152; ATPASE_ALPHA_BETA; 1; .

World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server

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