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Searching in 'World-2DPAGE Repository [0019]' for entry matching: P63010




World-2DPAGE Repository (0019):  P63010


P63010


General information about the entry
View entry in simple text format
Entry nameAP2B1_HUMAN
Primary accession numberP63010
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=AP-2 complex subunit beta; AltName: Full=AP105B; AltName: Full=Adapter-related protein complex 2 beta subunit; AltName: Full=Adaptor protein complex AP-2 subunit beta; AltName: Full=Beta-2-adaptin; AltName: Full=Beta-adaptin; AltName: Full=Clathrin assembly protein complex 2 beta large chain; AltName: Full=Plasma membrane adaptor HA2/AP2 adaptin beta subunit;.
Gene nameName=AP2B1
Synonyms=ADTB2, CLAPB1
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1111/j.1471-4159.2010.06719.x;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
HIPP_SYNAP
  map experimental info
 
HIPP_SYNAP

MAP LOCATIONS:
pI=5.22; Mw=105398  [identification data]

IDENTIFICATION: SPOT 144: Peptides number=7. SeqCov=8.1%. MOWSE score=1.32E+6 [1].
MAPPING (identification):
SPOT 144: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-ProtP63010; AP2B1_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameAP2B1_HUMAN
Primary accession numberP63010
Secondary accession number(s) A6NJP3 P21851 Q96J19
Sequence was last modified on August 31, 2004 (version 1)
Annotations were last modified on December 14, 2011 (version 90)
Name and origin of the protein
DescriptionRecName: Full=AP-2 complex subunit beta; AltName: Full=AP105B; AltName: Full=Adapter-related protein complex 2 beta subunit; AltName: Full=Adaptor protein complex AP-2 subunit beta; AltName: Full=Beta-2-adaptin; AltName: Full=Beta-adaptin; AltName: Full=Clathrin assembly protein complex 2 beta large chain; AltName: Full=Plasma membrane adaptor HA2/AP2 adaptin beta subunit;
Gene nameName=AP2B1
Synonyms=ADTB2, CLAPB1
Encoded onName=AP2B1; Synonyms=ADTB2, CLAPB1
Keywords3D-structure; Acetylation; Alternative splicing; Cell membrane; Coated pit; Complete proteome; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transport.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM34175; AAA35583.1; -; mRNA
EMBLAC006237; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLCH471147; EAW80133.1; -; Genomic_DNA
EMBLBC006201; AAH06201.1; -; mRNA
IPIIPI00784156; -; .
IPIIPI00784366; -; .
PIRA35553; A35553; .
RefSeqNP_001025177.1; NM_001030006.1; .
RefSeqNP_001273.1; NM_001282.2; .
UniGeneHs.514819; -; .
PDB1E42; X-ray; 1.70 A; A/B=701-937
PDB2G30; X-ray; 1.60 A; A=701-937
PDB2IV8; X-ray; 2.80 A; A=700-937
PDB2IV9; X-ray; 1.90 A; A/B=700-937
PDB2JKR; X-ray; 2.98 A; B/E=1-591
PDB2JKT; X-ray; 3.40 A; B/E=1-591
PDB2VGL; X-ray; 2.59 A; B=1-591
PDB2XA7; X-ray; 3.10 A; B=1-592
PDBsum1E42; -; .
PDBsum2G30; -; .
PDBsum2IV8; -; .
PDBsum2IV9; -; .
PDBsum2JKR; -; .
PDBsum2JKT; -; .
PDBsum2VGL; -; .
PDBsum2XA7; -; .
ProteinModelPortalP63010; -; .
SMRP63010; 4-582; 705-937; .
IntActP63010; 32; .
MINTMINT-256705; -; .
STRINGP63010; -; .
PhosphoSiteP63010; -; .
DMDM51702211; -; .
PRIDEP63010; -; .
EnsemblENST00000262325; ENSP00000262325; ENSG00000006125; .
GeneID163; -; .
KEGGhsa:163; -; .
UCSCuc002hjq.1; human; .
UCSCuc002hjr.1; human; .
CTD163; -; .
GeneCardsGC17P030099; -; .
HGNCHGNC:563; AP2B1; .
HPACAB017631; -; .
MIM601025; gene; .
neXtProtNX_P63010; -; .
PharmGKBPA24854; -; .
eggNOGprNOG09520; -; .
HOVERGENHBG050515; -; .
OMADCHLNAD; -; .
OrthoDBEOG4PG607; -; .
PhylomeDBP63010; -; .
ReactomeREACT_111045; Developmental Biology; .
ReactomeREACT_111102; Signal Transduction; .
ReactomeREACT_13685; Neuronal System; .
ReactomeREACT_6185; HIV Infection; .
NextBio653; -; .
ArrayExpressP63010; -; .
BgeeP63010; -; .
CleanExHS_AP2B1; -; .
GenevestigatorP63010; -; .
GermOnlineENSG00000006125; Homo sapiens; .
GOGO:0030131; C:clathrin adaptor complex; IEA:InterPro; .
GOGO:0005905; C:coated pit; IEA:UniProtKB-SubCell; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0030666; C:endocytic vesicle membrane; TAS:Reactome; .
GOGO:0005886; C:plasma membrane; TAS:Reactome; .
GOGO:0030276; F:clathrin binding; IPI:UniProtKB; .
GOGO:0008565; F:protein transporter activity; IEA:InterPro; .
GOGO:0007411; P:axon guidance; TAS:Reactome; .
GOGO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome; .
GOGO:0006886; P:intracellular protein transport; IEA:InterPro; .
GOGO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome; .
GOGO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome; .
GOGO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome; .
GOGO:0007268; P:synaptic transmission; TAS:Reactome; .
GOGO:0016192; P:vesicle-mediated transport; IEA:InterPro; .
GOGO:0016032; P:viral reproduction; TAS:Reactome; .
InterProIPR016342; AP_complex_bsu; .
InterProIPR011989; ARM-like; .
InterProIPR016024; ARM-type_fold; .
InterProIPR012295; Beta2_adaptin/TATA-box-bd_C; .
InterProIPR002553; Clathrin/coatomer_adapt-like_N; .
InterProIPR008152; Clathrin_a/b/g-adaptin_app_Ig; .
InterProIPR013037; Clathrin_b-adaptin_app_Ig-like; .
InterProIPR015151; Clathrin_b-adaptin_app_sub_C; .
InterProIPR009028; Coatomer/calthrin_app_sub_C; .
InterProIPR013041; Coatomer/clathrin_app_Ig-like; .
Gene3DG3DSA:1.25.10.10; ARM-like; 1; .
Gene3DG3DSA:3.30.310.10; b_Adaptin_TBP_C; 1; .
Gene3DG3DSA:2.60.40.1150; Clathrin_b-adaptin_app_Ig-like; 1; .
KOK11825; -; .
PfamPF01602; Adaptin_N; 1; .
PfamPF02883; Alpha_adaptinC2; 1; .
PfamPF09066; B2-adapt-app_C; 1; .
PIRSFPIRSF002291; AP_complex_beta; 1; .
SMARTSM00809; Alpha_adaptinC2; 1; .
SUPFAMSSF55711; AP2_adap_app; 1; .
SUPFAMSSF48371; ARM-type_fold; 1; .
SUPFAMSSF49348; Clath_adapt; 1; .





Searching in 'World-2DPAGE Repository [0001]' for entry matching: P63010




World-2DPAGE Repository (0001):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0001)



Searching in 'World-2DPAGE Repository [0002]' for entry matching: P63010




World-2DPAGE Repository (0002):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0002)



Searching in 'World-2DPAGE Repository [0003]' for entry matching: P63010




World-2DPAGE Repository (0003):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0003)



Searching in 'World-2DPAGE Repository [0004]' for entry matching: P63010




World-2DPAGE Repository (0004):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0004)



Searching in 'World-2DPAGE Repository [0005]' for entry matching: P63010




World-2DPAGE Repository (0005):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0005)



Searching in 'World-2DPAGE Repository [0006]' for entry matching: P63010




World-2DPAGE Repository (0006):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0006)



Searching in 'World-2DPAGE Repository [0007]' for entry matching: P63010




World-2DPAGE Repository (0007):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0007)



Searching in 'World-2DPAGE Repository [0008]' for entry matching: P63010




World-2DPAGE Repository (0008):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0008)



Searching in 'World-2DPAGE Repository [0009]' for entry matching: P63010




World-2DPAGE Repository (0009):  P63010

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Searching in 'World-2DPAGE Repository [0010]' for entry matching: P63010




World-2DPAGE Repository (0010):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0010)



Searching in 'World-2DPAGE Repository [0011]' for entry matching: P63010




World-2DPAGE Repository (0011):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0011)



Searching in 'World-2DPAGE Repository [0012]' for entry matching: P63010




World-2DPAGE Repository (0012):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0012)



Searching in 'World-2DPAGE Repository [0014]' for entry matching: P63010




World-2DPAGE Repository (0014):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0014)



Searching in 'World-2DPAGE Repository [0017]' for entry matching: P63010




World-2DPAGE Repository (0017):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0017)



Searching in 'World-2DPAGE Repository [0018]' for entry matching: P63010




World-2DPAGE Repository (0018):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0018)



Searching in 'World-2DPAGE Repository [0020]' for entry matching: P63010




World-2DPAGE Repository (0020):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0020)



Searching in 'World-2DPAGE Repository [0021]' for entry matching: P63010




World-2DPAGE Repository (0021):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0021)



Searching in 'World-2DPAGE Repository [0022]' for entry matching: P63010




World-2DPAGE Repository (0022):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0022)



Searching in 'World-2DPAGE Repository [0023]' for entry matching: P63010




World-2DPAGE Repository (0023):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0023)



Searching in 'World-2DPAGE Repository [0024]' for entry matching: P63010




World-2DPAGE Repository (0024):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0024)



Searching in 'World-2DPAGE Repository [0026]' for entry matching: P63010




World-2DPAGE Repository (0026):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0026)



Searching in 'World-2DPAGE Repository [0027]' for entry matching: P63010




World-2DPAGE Repository (0027):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0027)



Searching in 'World-2DPAGE Repository [0029]' for entry matching: P63010




World-2DPAGE Repository (0029):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0029)



Searching in 'World-2DPAGE Repository [0030]' for entry matching: P63010




World-2DPAGE Repository (0030):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0030)



Searching in 'World-2DPAGE Repository [0031]' for entry matching: P63010




World-2DPAGE Repository (0031):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0031)



Searching in 'World-2DPAGE Repository [0032]' for entry matching: P63010




World-2DPAGE Repository (0032):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0032)



Searching in 'World-2DPAGE Repository [0034]' for entry matching: P63010




World-2DPAGE Repository (0034):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0034)



Searching in 'World-2DPAGE Repository [0035]' for entry matching: P63010




World-2DPAGE Repository (0035):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0035)



Searching in 'World-2DPAGE Repository [0036]' for entry matching: P63010




World-2DPAGE Repository (0036):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0036)



Searching in 'World-2DPAGE Repository [0037]' for entry matching: P63010




World-2DPAGE Repository (0037):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0037)



Searching in 'World-2DPAGE Repository [0038]' for entry matching: P63010




World-2DPAGE Repository (0038):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0038)



Searching in 'World-2DPAGE Repository [0039]' for entry matching: P63010




World-2DPAGE Repository (0039):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0039)



Searching in 'World-2DPAGE Repository [0040]' for entry matching: P63010




World-2DPAGE Repository (0040):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0040)



Searching in 'World-2DPAGE Repository [0042]' for entry matching: P63010




World-2DPAGE Repository (0042):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0042)



Searching in 'World-2DPAGE Repository [0043]' for entry matching: P63010




World-2DPAGE Repository (0043):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0043)



Searching in 'World-2DPAGE Repository [0044]' for entry matching: P63010




World-2DPAGE Repository (0044):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0044)



Searching in 'World-2DPAGE Repository [0046]' for entry matching: P63010




World-2DPAGE Repository (0046):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0046)



Searching in 'World-2DPAGE Repository [0047]' for entry matching: P63010




World-2DPAGE Repository (0047):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0047)



Searching in 'World-2DPAGE Repository [0050]' for entry matching: P63010




World-2DPAGE Repository (0050):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0050)



Searching in 'World-2DPAGE Repository [0051]' for entry matching: P63010




World-2DPAGE Repository (0051):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0051)



Searching in 'World-2DPAGE Repository [0053]' for entry matching: P63010




World-2DPAGE Repository (0053):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0053)



Searching in 'World-2DPAGE Repository [0054]' for entry matching: P63010




World-2DPAGE Repository (0054):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0054)



Searching in 'World-2DPAGE Repository [0056]' for entry matching: P63010




World-2DPAGE Repository (0056):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0056)



Searching in 'World-2DPAGE Repository [0059]' for entry matching: P63010




World-2DPAGE Repository (0059):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0059)



Searching in 'World-2DPAGE Repository [0061]' for entry matching: P63010




World-2DPAGE Repository (0061):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0061)



Searching in 'World-2DPAGE Repository [0062]' for entry matching: P63010




World-2DPAGE Repository (0062):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0062)



Searching in 'World-2DPAGE Repository [0063]' for entry matching: P63010




World-2DPAGE Repository (0063):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0063)



Searching in 'World-2DPAGE Repository [0066]' for entry matching: P63010




World-2DPAGE Repository (0066):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0066)



Searching in 'World-2DPAGE Repository [0068]' for entry matching: P63010




World-2DPAGE Repository (0068):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0068)



Searching in 'World-2DPAGE Repository [0069]' for entry matching: P63010




World-2DPAGE Repository (0069):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0069)



Searching in 'World-2DPAGE Repository [0076]' for entry matching: P63010




World-2DPAGE Repository (0076):  P63010

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Searching in 'World-2DPAGE Repository [0077]' for entry matching: P63010




World-2DPAGE Repository (0077):  P63010

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Searching in 'World-2DPAGE Repository [0080]' for entry matching: P63010




World-2DPAGE Repository (0080):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0080)



Searching in 'World-2DPAGE Repository [0084]' for entry matching: P63010




World-2DPAGE Repository (0084):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0084)



Searching in 'World-2DPAGE Repository [0085]' for entry matching: P63010




World-2DPAGE Repository (0085):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0085)



Searching in 'World-2DPAGE Repository [0088]' for entry matching: P63010




World-2DPAGE Repository (0088):  P63010

This protein does not exist in the current release of World-2DPAGE Repository (0088)




World-2DPAGE Repository image

World-2DPAGE Repository (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server