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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0019]' for entry matching: P63018 World-2DPAGE Repository (0019):  P63018 P63018 General information about the entry View entry in simple text format Entry name HSP7C_RAT Primary accession number P63018 integrated into World-2DPAGE Repository (0019) on  December 9, 2009 (release 1) 2D Annotations were last modified on May 30, 2011 (version 2) General Annotations were last modified on  January 13, 2012 (version 2) Name and origin of the protein Description RecName: Full=Heat shock cognate 71 kDa protein; AltName: Full=Heat shock 70 kDa protein 8;. Gene name Name=Hspa8 Synonyms=Hsc70, Hsc73 Annotated species Rattus norvegicus (Rat) [TaxID: 10116] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1111/j.1471-4159.2010.06719.x; VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M. ''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome'' J of Neurochemistry 113(6):1577-1588 (2010) 2D PAGE maps for identified proteins How to interpret a protein HIPP_SYNAP {Rat hippocampal synaptoproteome} Rattus norvegicus (Rat) Tissue: Hippocampus   map experimental info   HIPP_SYNAP MAP LOCATIONS: SPOT 295: pI=5.37; Mw=71055   [identification data] SPOT 303: pI=5.37; Mw=71055   [identification data] SPOT 994: pI=5.37; Mw=71055   [identification data] IDENTIFICATION: SPOT 295: Peptides number=8. SeqCov=18.3%. MOWSE score=3.06E+9 [1] SPOT 303: Peptides number=10. SeqCov=24.3%. MOWSE score=2.45E+9 [1]; SPOT 994: Peptides number=12. SeqCov=27.6%. MOWSE score=4.65E+13 [1]. MAPPING (identification): SPOT 295: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 303: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 994: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Willard Freeman, Penn State College of Medicine, USA Cross-references UniProtKB/Swiss-Prot P63018; HSP7C_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_12 Entry name HSP7C_RAT Primary accession number P63018 Secondary accession number(s) P08109 P12225 Q4FZY7 Q62373 Q62374 Q62375 Sequence was last modified on  August 1, 1988 (version 1) Annotations were last modified on  November 16, 2011 (version 84) Name and origin of the protein Description RecName: Full=Heat shock cognate 71 kDa protein; AltName: Full=Heat shock 70 kDa protein 8; Gene name Name=Hspa8 Synonyms=Hsc70, Hsc73 Encoded on Name=Hspa8; Synonyms=Hsc70, Hsc73 Keywords 3D-structure; Acetylation; ATP-binding; Chaperone; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleotide-binding; Phosphoprotein; Reference proteome; Repressor; Stress response; Transcription; Transcription regulation; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL Y00054; CAA68265.1; -; Genomic_DNA EMBL M11942; AAA41354.1; -; mRNA EMBL BC061547; AAH61547.1; -; mRNA EMBL BC098914; AAH98914.1; -; mRNA IPI IPI00208205; -; . PIR S07197; S07197; . RefSeq NP_077327.1; NM_024351.2; . UniGene Rn.120392; -; . UniGene Rn.201298; -; . PDB 1CKR; NMR; -; A=385-543 PDB 1Q2G; Model; -; C=385-543 PDB 1UD0; X-ray; 3.45 A; A/B/C/D=542-646 PDB 2V7Z; X-ray; 3.50 A; A/B=1-543 PDB 7HSC; NMR; -; A=385-543 PDBsum 1CKR; -; . PDBsum 1Q2G; -; . PDBsum 1UD0; -; . PDBsum 2V7Z; -; . PDBsum 7HSC; -; . ProteinModelPortal P63018; -; . SMR P63018; 1-621; . IntAct P63018; 5; . MINT MINT-2514077; -; . STRING P63018; -; . PhosphoSite P63018; -; . World-2DPAGE 0004:P63018; -; . PRIDE P63018; -; . GeneID 24468; -; . KEGG rno:24468; -; . UCSC BC061547; rat; . CTD 3312; -; . RGD 621725; Hspa8; . eggNOG maNOG11692; -; . GeneTree ENSGT00550000074467; -; . HOVERGEN HBG051845; -; . OrthoDB EOG4W6NVK; -; . PhylomeDB P63018; -; . NextBio 603401; -; . Genevestigator P63018; -; . GO GO:0070062; C:extracellular vesicular exosome; IDA:RGD; . GO GO:0042470; C:melanosome; IEA:UniProtKB-SubCell; . GO GO:0043005; C:neuron projection; IDA:RGD; . GO GO:0043025; C:neuronal cell body; IDA:RGD; . GO GO:0043234; C:protein complex; IDA:RGD; . GO GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB; . GO GO:0005625; C:soluble fraction; IDA:RGD; . GO GO:0008021; C:synaptic vesicle; IDA:RGD; . GO GO:0043531; F:ADP binding; IDA:RGD; . GO GO:0005524; F:ATP binding; IDA:RGD; . GO GO:0042623; F:ATPase activity; coupled; IDA:RGD GO GO:0005102; F:receptor binding; IPI:RGD; . GO GO:0051082; F:unfolded protein binding; IMP:RGD; . GO GO:0051085; P:chaperone mediated protein folding requiring cofactor; IDA:RGD; . GO GO:0045892; P:negative regulation of transcription; DNA-dependent; ISS:UniProtKB GO GO:0006950; P:response to stress; IEA:UniProtKB-KW; . GO GO:0006351; P:transcription; DNA-dependent; IEA:UniProtKB-KW InterPro IPR018181; Heat_shock_70_CS; . InterPro IPR001023; Hsp70; . InterPro IPR013126; Hsp_70; . KO K03283; -; . PANTHER PTHR19375; Hsp70; 1; . Pfam PF00012; HSP70; 1; . PRINTS PR00301; HEATSHOCK70; . PROSITE PS00297; HSP70_1; 1; . PROSITE PS00329; HSP70_2; 1; . PROSITE PS01036; HSP70_3; 1; . World-2DPAGE Repository (search AC)