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Searching in 'World-2DPAGE Repository [0027]' for entry matching: P63038




World-2DPAGE Repository (0027):  P63038


P63038


General information about the entry
View entry in simple text format
Entry nameCH60_MOUSE
Primary accession numberP63038
integrated into World-2DPAGE Repository (0027) on September 30, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=60 kDa heat shock protein, mitochondrial; AltName: Full=60 kDa chaperonin; AltName: Full=Chaperonin 60; Short=CPN60; AltName: Full=HSP-65; AltName: Full=Heat shock protein 60; Short=HSP-60; Short=Hsp60; AltName: Full=Mitochondrial matrix protein P1; Flags: Precursor;.
Gene nameName=Hspd1
Synonyms=Hsp60
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/prca.201000103;
Blutke A., Block C., Berendt F., Herbach N., Kemter E., Amann K., Frolich T., Arnold G.J., Wanke R.
''Differential glomerular proteome analysis of two murine nephropathy models at onset of albuminuria''
Proteomics - Clinical Applications 5(6):375-381 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

GIPRDN_4-7 {glomerular protein lysates of a GIPRdn-tg animal}
Mus musculus (Mouse)
GIPRDN_4-7
  map experimental info
 
GIPRDN_4-7

MAP LOCATIONS:
pI=5.33; Mw=58000  [identification data]

EXPRESSION:
SPOT 7: Avg ratio GIPRdn-tg vs. control=1.77 (p-value=0.0027) [1].

IDENTIFICATION: SPOT 7: SeqCov=46%. Mascot protein score=723 [1].
MAPPING (identification):
SPOT 7: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Andreas Blutke, Institute of Veterinary Pathology, University Munich, Germany
Cross-references
REPRODUCTION-2DPAGEIPI00308885; IPI00308885.
REPRODUCTION-2DPAGEP63038; P63038.
SWISS-2DPAGEP63038; CH60_MOUSE.
UCD-2DPAGEP63038; CH60_MOUSE.
UniProtKB/Swiss-ProtP63038; CH60_MOUSE.
World-2DPAGE RepositoryP63038; CH60_MOUSE.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameCH60_MOUSE
Primary accession numberP63038
Secondary accession number(s) P19226 P19227 P97602 Q3KQP2 Q3UIP0 Q8C2C7 Q8VEF4
Sequence was last modified on August 31, 2004 (version 1)
Annotations were last modified on November 16, 2011 (version 83)
Name and origin of the protein
DescriptionRecName: Full=60 kDa heat shock protein, mitochondrial; AltName: Full=60 kDa chaperonin; AltName: Full=Chaperonin 60; Short=CPN60; AltName: Full=HSP-65; AltName: Full=Heat shock protein 60; Short=HSP-60; Short=Hsp60; AltName: Full=Mitochondrial matrix protein P1; Flags: Precursor;
Gene nameName=Hspd1
Synonyms=Hsp60
Encoded onName=Hspd1; Synonyms=Hsp60
KeywordsAcetylation; Alternative splicing; ATP-binding; Chaperone; Complete proteome; Direct protein sequencing; Mitochondrion; Nucleotide-binding; Phosphoprotein; Reference proteome; Transit peptide.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX55023; CAA38762.1; -; mRNA
EMBLAK088844; BAC40607.1; -; mRNA
EMBLAK143882; BAE25581.1; -; mRNA
EMBLAK146831; BAE27466.1; -; mRNA
EMBLBC016400; AAH16400.1; -; mRNA
EMBLBC018545; AAH18545.1; -; mRNA
EMBLBC106112; AAI06113.1; ALT_SEQ; mRNA
EMBLX53584; CAA37653.1; -; mRNA
IPIIPI00308885; -; .
IPIIPI00845678; -; .
PIRS13084; HHMS60; .
RefSeqNP_034607.3; NM_010477.4; .
UniGeneMm.1777; -; .
ProteinModelPortalP63038; -; .
SMRP63038; 27-554; .
IntActP63038; 8; .
MINTMINT-1860238; -; .
STRINGP63038; -; .
SWISS-2DPAGEP63038; -; .
REPRODUCTION-2DPAGEIPI00308885; -; .
REPRODUCTION-2DPAGEP63038; -; .
UCD-2DPAGEP19227; -; .
UCD-2DPAGEP63038; -; .
PRIDEP63038; -; .
EnsemblENSMUST00000027123; ENSMUSP00000027123; ENSMUSG00000025980; .
GeneID15510; -; .
KEGGmmu:15510; -; .
UCSCuc007bab.2; mouse; .
CTD3329; -; .
MGIMGI:96242; Hspd1; .
eggNOGroNOG14286; -; .
GeneTreeENSGT00390000005727; -; .
HOVERGENHBG001982; -; .
InParanoidP63038; -; .
OMAVQSIIPA; -; .
OrthoDBEOG4PK27J; -; .
PhylomeDBP63038; -; .
NextBio288418; -; .
PMAP-CutDBP63038; -; .
BgeeP63038; -; .
CleanExMM_HSPD1; -; .
GenevestigatorP63038; -; .
GermOnlineENSMUSG00000025980; Mus musculus; .
GOGO:0005743; C:mitochondrial inner membrane; IDA:MGI; .
GOGO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell; .
GOGO:0044459; C:plasma membrane part; IDA:MGI; .
GOGO:0030141; C:stored secretory granule; IDA:MGI; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0001530; F:lipopolysaccharide binding; IDA:BHF-UCL; .
GOGO:0032727; P:positive regulation of interferon-alpha production; IDA:MGI; .
GOGO:0032729; P:positive regulation of interferon-gamma production; IDA:BHF-UCL; .
GOGO:0050870; P:positive regulation of T cell activation; IDA:BHF-UCL; .
GOGO:0042110; P:T cell activation; IDA:MGI; .
InterProIPR018370; Chaperonin_Cpn60_CS; .
InterProIPR001844; Chaprnin_Cpn60; .
InterProIPR002423; Cpn60/TCP-1; .
KOK04077; -; .
PANTHERPTHR11353; Cpn60/TCP-1; 1; .
PfamPF00118; Cpn60_TCP1; 1; .
PRINTSPR00298; CHAPERONIN60; .
SUPFAMSSF48592; GroEL-ATPase; 1; .
TIGRFAMsTIGR02348; GroEL; 1; .
PROSITEPS00296; CHAPERONINS_CPN60; 1; .



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World-2DPAGE Repository (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server