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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0030]' for entry matching: P63159 World-2DPAGE Repository (0030):  P63159 P63159 General information about the entry View entry in simple text format Entry name HMGB1_RAT Primary accession number P63159 integrated into World-2DPAGE Repository (0030) on  November 9, 2010 (release 1) 2D Annotations were last modified on June 21, 2011 (version 2) General Annotations were last modified on  November 23, 2011 (version 2) Name and origin of the protein Description RecName: Full=High mobility group protein B1; AltName: Full=Amphoterin; AltName: Full=Heparin-binding protein p30; AltName: Full=High mobility group protein 1; Short=HMG-1;. Gene name Name=Hmgb1 Synonyms=Hmg-1, Hmg1 Annotated species Rattus norvegicus (Rat) [TaxID: 10116] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000006; D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C. ''Two-dimensional gel proteome reference map of INS-1E cells'' Proteomics 11(7):1365-1369 (2011) 2D PAGE maps for identified proteins How to interpret a protein RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7} Rattus norvegicus (Rat)   map experimental info   RAT_INS1E_4-7 MAP LOCATIONS: SPOT 2079: pI=6.33; Mw=29742   [identification data] IDENTIFICATION: SPOT 2079: Mascot protein score=47. Number of peptides=2 [1]. MAPPING (identification): SPOT 2079: Tandem mass spectrometry [1]. Copyright Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium Cross-references UniProtKB/Swiss-Prot P63159; HMGB1_RAT. World-2DPAGE Repository P63159; HMGB1_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name HMGB1_RAT Primary accession number P63159 Secondary accession number(s) P07155 P27109 P27428 Q548R9 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  November 16, 2011 (version 80) Name and origin of the protein Description RecName: Full=High mobility group protein B1; AltName: Full=Amphoterin; AltName: Full=Heparin-binding protein p30; AltName: Full=High mobility group protein 1; Short=HMG-1; Gene name Name=Hmgb1 Synonyms=Hmg-1, Hmg1 Encoded on Name=Hmgb1; Synonyms=Hmg-1, Hmg1 Keywords 3D-structure; Acetylation; Chromosome; Complete proteome; Cytoplasm; Direct protein sequencing; DNA-binding; Heparin-binding; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; Repeat; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M64986; AAA40729.1; -; mRNA EMBL Y00463; CAA68526.1; -; mRNA EMBL AF275734; AAF82799.1; -; mRNA EMBL BC061779; AAH61779.1; -; mRNA EMBL BC081839; AAH81839.1; -; mRNA EMBL BC088402; AAH88402.1; -; mRNA IPI IPI00555214; -; . PIR A41175; NSRTH1; . RefSeq NP_037095.1; NM_012963.2; . UniGene Rn.144565; -; . UniGene Rn.15185; -; . UniGene Rn.4121; -; . PDB 1AAB; NMR; -; A=2-84 PDB 1CKT; X-ray; 2.50 A; A=8-77 PDB 1HME; NMR; -; A=89-165 PDB 1HMF; NMR; -; A=89-165 PDB 2GZK; NMR; -; A=82-165 PDBsum 1AAB; -; . PDBsum 1CKT; -; . PDBsum 1HME; -; . PDBsum 1HMF; -; . PDBsum 2GZK; -; . ProteinModelPortal P63159; -; . SMR P63159; 5-166; . STRING P63159; -; . PhosphoSite P63159; -; . PRIDE P63159; -; . GeneID 25459; -; . KEGG rno:25459; -; . UCSC BC061779; rat; . CTD 3146; -; . RGD 2802; Hmgb1; . eggNOG roNOG11154; -; . GeneTree ENSGT00560000076717; -; . HOVERGEN HBG009000; -; . InParanoid P63159; -; . OrthoDB EOG4KWJV1; -; . PhylomeDB P63159; -; . NextBio 606729; -; . Genevestigator P63159; -; . GermOnline ENSRNOG00000030351; Rattus norvegicus; . GO GO:0005694; C:chromosome; IEA:UniProtKB-SubCell; . GO GO:0005737; C:cytoplasm; IDA:RGD; . GO GO:0005615; C:extracellular space; IDA:RGD; . GO GO:0005634; C:nucleus; IDA:RGD; . GO GO:0008097; F:5S rRNA binding; IDA:RGD; . GO GO:0003681; F:bent DNA binding; IDA:MGI; . GO GO:0000402; F:crossed form four-way junction DNA binding; IDA:MGI; . GO GO:0005125; F:cytokine activity; IDA:UniProtKB; . GO GO:0008301; F:DNA bending activity; IDA:RGD; . GO GO:0003690; F:double-stranded DNA binding; IDA:RGD; . GO GO:0051861; F:glycolipid binding; IDA:RGD; . GO GO:0008201; F:heparin binding; IDA:RGD; . GO GO:0000401; F:open form four-way junction DNA binding; IDA:MGI; . GO GO:0042277; F:peptide binding; IDA:RGD; . GO GO:0046983; F:protein dimerization activity; IDA:RGD; . GO GO:0050786; F:RAGE receptor binding; IPI:UniProtKB; . GO GO:0003697; F:single-stranded DNA binding; IDA:RGD; . GO GO:0008134; F:transcription factor binding; IDA:RGD; . GO GO:0031532; P:actin cytoskeleton reorganization; IMP:RGD; . GO GO:0000902; P:cell morphogenesis; IMP:RGD; . GO GO:0071347; P:cellular response to interleukin-1; IEP:RGD; . GO GO:0006935; P:chemotaxis; IDA:RGD; . GO GO:0007623; P:circadian rhythm; IEP:RGD; . GO GO:0032392; P:DNA geometric change; IDA:MGI; . GO GO:0050930; P:induction of positive chemotaxis; IDA:MGI; . GO GO:0050831; P:male-specific defense response to bacterium; IDA:RGD; . GO GO:0051450; P:myoblast proliferation; IMP:RGD; . GO GO:0008156; P:negative regulation of DNA replication; IDA:RGD; . GO GO:0031175; P:neuron projection development; IGI:UniProtKB; . GO GO:0002053; P:positive regulation of mesenchymal cell proliferation; IDA:MGI; . GO GO:0045931; P:positive regulation of mitotic cell cycle; IDA:MGI; . GO GO:0033034; P:positive regulation of myeloid cell apoptosis; IDA:RGD; . GO GO:0045663; P:positive regulation of myoblast differentiation; IMP:RGD; . GO GO:0010976; P:positive regulation of neuron projection development; IMP:RGD; . GO GO:0014911; P:positive regulation of smooth muscle cell migration; IMP:RGD; . GO GO:0050727; P:regulation of inflammatory response; IDA:RGD; . GO GO:0042493; P:response to drug; IEP:RGD; . GO GO:0009749; P:response to glucose stimulus; IEP:RGD; . GO GO:0009408; P:response to heat; IEP:RGD; . GO GO:0032868; P:response to insulin stimulus; IEP:RGD; . GO GO:0034341; P:response to interferon-gamma; IMP:RGD; . GO GO:0032496; P:response to lipopolysaccharide; IEP:RGD; . InterPro IPR011989; ARM-like; . InterPro IPR017967; HMG_boxA_CS; . InterPro IPR000910; HMG_HMG1/HMG2; . InterPro IPR000135; HMG_HMG1/HMG2_subgr; . InterPro IPR009071; HMG_superfamily; . Gene3D G3DSA:1.25.10.10; ARM-like; 1; . Gene3D G3DSA:1.10.30.10; HMG-box; 2; . KO K10802; -; . Pfam PF00505; HMG_box; 2; . PRINTS PR00886; HIGHMOBLTY12; . SMART SM00398; HMG; 2; . SUPFAM SSF47095; HMG-box; 2; . PROSITE PS00353; HMG_BOX_1; 1; . PROSITE PS50118; HMG_BOX_2; 2; . World-2DPAGE Repository (search AC)