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Searching in 'World-2DPAGE Repository [0019]' for entry matching: P68369




World-2DPAGE Repository (0019):  P68369


P68369


General information about the entry
View entry in simple text format
Entry nameTBA1A_MOUSE
Primary accession numberP68369
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Tubulin alpha-1A chain; AltName: Full=Alpha-tubulin 1; AltName: Full=Alpha-tubulin isotype M-alpha-1; AltName: Full=Tubulin alpha-1 chain;.
Gene nameName=Tuba1a
Synonyms=Tuba1
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1111/j.1471-4159.2010.06719.x;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
HIPP_SYNAP
  map experimental info
 
HIPP_SYNAP

MAP LOCATIONS:
pI=4.94; Mw=50787  [identification data]

IDENTIFICATION: SPOT 1167: Peptides number=8. SeqCov=24.4%. MOWSE score=2.40E+11 [1].
MAPPING (identification):
SPOT 1167: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-ProtP68369; TBA1A_MOUSE.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameTBA1A_MOUSE
Primary accession numberP68369
Secondary accession number(s) P02551 P05210 P05212 Q3TGF0 Q3TIW2 Q3TPJ1 Q3ULN1 Q5XJF8
Sequence was last modified on July 21, 1986 (version 1)
Annotations were last modified on November 16, 2011 (version 83)
Name and origin of the protein
DescriptionRecName: Full=Tubulin alpha-1A chain; AltName: Full=Alpha-tubulin 1; AltName: Full=Alpha-tubulin isotype M-alpha-1; AltName: Full=Tubulin alpha-1 chain;
Gene nameName=Tuba1a
Synonyms=Tuba1
Encoded onName=Tuba1a; Synonyms=Tuba1
KeywordsAcetylation; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; GTP-binding; Microtubule; Nucleotide-binding; Phosphoprotein; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM13445; AAA40499.1; -; mRNA
EMBLAK077529; BAC36848.1; -; mRNA
EMBLAK145404; BAE26417.1; -; mRNA
EMBLAK146983; BAE27586.1; -; mRNA
EMBLAK164335; BAE37745.1; -; mRNA
EMBLAK167687; BAE39734.1; -; mRNA
EMBLAK168762; BAE40598.1; -; mRNA
EMBLAK169610; BAE41258.1; -; mRNA
EMBLBC056169; AAH56169.1; -; mRNA
EMBLBC083343; AAH83343.1; -; mRNA
EMBLBC083345; AAH83345.1; -; mRNA
EMBLBC085256; AAH85256.1; -; mRNA
EMBLM28729; AAA40506.1; -; mRNA
EMBLBC083344; AAH83344.1; -; mRNA
IPIIPI00110753; -; .
PIRI77424; I77424; .
RefSeqNP_035783.1; NM_011653.2; .
UniGeneMm.439690; -; .
ProteinModelPortalP68369; -; .
SMRP68369; 1-440; .
IntActP68369; 9; .
MINTMINT-3288915; -; .
STRINGP68369; -; .
PhosphoSiteP68369; -; .
SWISS-2DPAGEP68369; -; .
PRIDEP68369; -; .
EnsemblENSMUST00000097014; ENSMUSP00000094778; ENSMUSG00000072235; .
GeneID22142; -; .
KEGGmmu:22142; -; .
CTD7846; -; .
MGIMGI:98869; Tuba1a; .
GeneTreeENSGT00600000084100; -; .
HOVERGENHBG000089; -; .
InParanoidP68369; -; .
OMAANHEANS; -; .
OrthoDBEOG44J2HZ; -; .
PhylomeDBP68369; -; .
NextBio302038; -; .
PMAP-CutDBP68369; -; .
ArrayExpressP68369; -; .
BgeeP68369; -; .
CleanExMM_TUBA1A; -; .
GenevestigatorP68369; -; .
GermOnlineENSMUSG00000072235; Mus musculus; .
GOGO:0005881; C:cytoplasmic microtubule; IDA:MGI; .
GOGO:0005525; F:GTP binding; IEA:UniProtKB-KW; .
GOGO:0003924; F:GTPase activity; IEA:InterPro; .
GOGO:0005198; F:structural molecule activity; IEA:InterPro; .
GOGO:0007018; P:microtubule-based movement; IEA:InterPro; .
GOGO:0051258; P:protein polymerization; IEA:InterPro; .
InterProIPR002452; Alpha_tubulin; .
InterProIPR008280; Tub_FtsZ_C; .
InterProIPR000217; Tubulin; .
InterProIPR018316; Tubulin/FtsZ_2-layer-sand-dom; .
InterProIPR023123; Tubulin_C; .
InterProIPR017975; Tubulin_CS; .
InterProIPR003008; Tubulin_FtsZ_GTPase; .
Gene3DG3DSA:3.30.1330.20; Tubulin/FtsZ_2-layer-sand-dom; 1; .
Gene3DG3DSA:1.10.287.600; Tubulin_C; 1; .
Gene3DG3DSA:3.40.50.1440; Tubulin_FtsZ; 1; .
KOK07374; -; .
PANTHERPTHR11588; Tubulin; 1; .
PfamPF00091; Tubulin; 1; .
PfamPF03953; Tubulin_C; 1; .
PRINTSPR01162; ALPHATUBULIN; .
PRINTSPR01161; TUBULIN; .
SMARTSM00864; Tubulin; 1; .
SMARTSM00865; Tubulin_C; 1; .
SUPFAMSSF55307; Tub_FtsZ_C; 1; .
SUPFAMSSF52490; Tubulin_FtsZ; 1; .
PROSITEPS00227; TUBULIN; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server