World-2DPAGE Repository

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.

References

[1]	MAPPING ON GEL PubMed=19343716; DOI=10.1002/pmic.200800664; [NCBI, EBI, Israel, Japan] Maurya D.K., Sundaram C.S., Bhargava P. ''Proteome profile of the mature rat olfactory bulb'' Proteomics 9(1):2593-2599 (2009)

2D PAGE maps for identified proteins

How to interpret a protein

OB21DSUB {2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb

map experimental info

OB21DSUB

MAP LOCATIONS:

SPOT 460:

pI=5.93; Mw=42000

[identification data]

SPOT 468:

pI=5.46; Mw=42000

[identification data]

MAPPING (identification):

SPOT 460: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 468: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India

Cross-references

UniProtKB/Swiss-Prot

P82471; GNAQ_RAT.

2D PAGE maps for identified proteins
How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry name	GNAQ_RAT
Primary accession number	P82471
Sequence was last modified on	July 7, 2009 (version 2)
Annotations were last modified on	December 14, 2011 (version 86)
Name and origin of the protein
Description	RecName: Full=Guanine nucleotide-binding protein G(q) subunit alpha; AltName: Full=Guanine nucleotide-binding protein alpha-q;
Gene name	Name=Gnaq
Encoded on	Name=Gnaq
Keywords	Acetylation; Complete proteome; GTP-binding; Lipoprotein; Magnesium; Metal-binding; Nucleotide-binding; Palmitate; Reference proteome; Transducer.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL	AF234260; AAF59930.1; -; mRNA
EMBL	L37294; AAB02848.1; -; mRNA
IPI	IPI00230868; -; .
RefSeq	NP_112298.1; NM_031036.1; .
UniGene	Rn.22817; -; .
STRING	P82471; -; .
PhosphoSite	P82471; -; .
World-2DPAGE	0004:P82471; -; .
PRIDE	P82471; -; .
GeneID	81666; -; .
KEGG	rno:81666; -; .
CTD	2776; -; .
RGD	620770; Gnaq; .
eggNOG	maNOG05363; -; .
HOVERGEN	HBG063184; -; .
InParanoid	P82471; -; .
NextBio	615248; -; .
ArrayExpress	P82471; -; .
Genevestigator	P82471; -; .
GermOnline	ENSRNOG00000014183; Rattus norvegicus; .
GO	GO:0005901; C:caveola; IDA:RGD; .
GO	GO:0005829; C:cytosol; IDA:RGD; .
GO	GO:0005834; C:heterotrimeric G-protein complex; IBA:RefGenome; .
GO	GO:0005624; C:membrane fraction; IDA:RGD; .
GO	GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome; .
GO	GO:0005525; F:GTP binding; IDA:RGD; .
GO	GO:0005096; F:GTPase activator activity; IBA:RefGenome; .
GO	GO:0003924; F:GTPase activity; IBA:RefGenome; .
GO	GO:0046872; F:metal ion binding; IEA:UniProtKB-KW; .
GO	GO:0004871; F:signal transducer activity; IBA:RefGenome; .
GO	GO:0031826; F:type 2A serotonin receptor binding; IMP:RGD; .
GO	GO:0007189; P:activation of adenylate cyclase activity by G-protein signaling pathway; IBA:RefGenome; .
GO	GO:0060158; P:activation of phospholipase C activity by dopamine receptor signaling pathway; IBA:RefGenome; .
GO	GO:0006916; P:anti-apoptosis; IMP:RGD; .
GO	GO:0007215; P:glutamate signaling pathway; IBA:RefGenome; .
GO	GO:0043267; P:negative regulation of potassium ion transport; IMP:RGD; .
GO	GO:0043065; P:positive regulation of apoptotic process; TAS:RGD; .
GO	GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD; .
GO	GO:0006471; P:protein ADP-ribosylation; IEA:InterPro; .
GO	GO:0001508; P:regulation of action potential; IBA:RefGenome; .
InterPro	IPR000654; Gprotein_alpha_Q; .
InterPro	IPR001019; Gprotein_alpha_su; .
InterPro	IPR011025; GproteinA_insert; .
Gene3D	G3DSA:1.10.400.10; GproteinA_insert; 1; .
KO	K04634; -; .
PANTHER	PTHR10218; Gprotein_alph_bd; 1; .
Pfam	PF00503; G-alpha; 1; .
PRINTS	PR00318; GPROTEINA; .
PRINTS	PR00442; GPROTEINAQ; .
SMART	SM00275; G_alpha; 1; .
SUPFAM	SSF47895; Transducn_insert; 1; .

World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server

0001
0002
0003
0004
0005
0006
0007
0008
0009
0010
0011
0012
0014
0017
0018
0019
0020
0021
0022
0023
0024
0026
0027
0029
0030
0031
0032
0034
0035
0036
0037
0038
0039
0040
0042
0043
0044
0046
0047
0050
0051
0053
0054
0056
0059
0061
0062
0063
0066
0068
0069
0076
0077
0080
0084
0085
0088